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Medical Microbiology Chapter 2
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C & H
elements that make up organic molecules (along with O, N, S, & P)
carbohydrates, proteins, lipids, nucleic acids
4 basic categories of organic molecules found in living organisms
dehydration reaction
method by which bonds between organic subunits in a polymer are created
hydrolysis
method by which bonds between organic subunits in a polymer are destroyed
pH
measure of hydrogen ions [H+=molar concentration] that determines acid/base
ionic bonds
attractions between ions of opposite charge; one atom loses electrons and another gains electrons
covalent bonds
form when 2 atoms share one or more pairs of electrons
hydrogen bonds
occur between polar molecules possessing hydrogen and oxygen
hydrophobic interaction
attraction of non polar molecules
inorganic compounds
lack carbon
acid
substance that dissociates into one or more H+
base
substance that dissociates into one or more OH-
salt
substance that dissociates into cations and anions (neither of which is H+ or OH-)
6.5-8.5
pH range in which most organisms grow best
generalizations for organic molecules
~all composed of subunits (monomers) joined together to form macromolecule (polymers)
~monomers are joined together by loss of H2O between monomers
~energy is required to join monomers together; released when broken
carbohydrate
monomer: monosaccharide
polymer: polysaccharide
lipid
monomer: glycerol + fatty adic
polymer: fats, oils, waxes
protein
monomer: amino acid
polymer: protein or polypeptide
nucleic acid
monomer: nucleotide
polymer: nucleic acid
monosaccharides
simple sugars with 3-7 carbon atoms
disaccharides
formed when 2 monosaccharides are joined by dehydration synthesis (broken by hydrolysis)
polysaccharides
made of many carbon rings; glycogen, starch, cellulose
peptide bonds
form between amino acids by dehydration synthesis
nucleotide
5 carbon sugar + phosphate group + nitrogen base
DNA
deoxyribose, double helix, AT, CG
RNA
ribose, AU, CG
ATP
ribose + adenine + 3 phosphate groups; important energy compound and part of RNA
immediate energy, stored energy, structural molecules
carbohydrate function
long-term energy storage, membrane components
lipid function
support, metabolic, transport, regulation, motion
protein function
storage of genetic information
nucleic acid function