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What are systolic regurgitant murmurs associated with?
Mitral or tricuspid regurgitation
What are systolic ejection murmurs associated with?
Aortic or pulmonic stenosis
What do diastolic murmurs suggest?
Aortic or pulmonic regurgitation
What are common red flags for congenital heart disease in puppies?
Loud diastolic or continuous murmur or a thrill
What characterizes an innocent puppy murmur?
Soft grade I-II systolic left-base murmur
When do innocent puppy murmurs often disappear?
12-16 weeks
What does both small pulmonary arteries and veins suggest?
Hypovolemia or right-to-left shunt
What does both large pulmonary arteries and veins suggest?
CHF or volume overload
What does pulmonary artery enlargement suggest?
Pulmonary hypertension
What does pulmonary vein enlargement suggest?
Left-sided CHF
What does VLAS assess?
Left atrial enlargement
Why is VLAS useful?
VHS can miss left atrial enlargement
What does a Valentine-shaped heart indicate in cats?
Biatrial enlargement
What does a small heart with small vessels and dark lungs suggest?
Hypovolemia
What is a focused cardiac ultrasound?
Targeted exam answering specific questions
What can a focused cardiac ultrasound assess?
Effusion tamponade masses and cardiac size/function
What must be enlarged with cardiogenic pulmonary edema?
Left atrium
What does cardiac troponin I indicate?
Myocardial injury
What is an important limitation of cardiac troponin I?
It is not specific for cardiac disease
What does NT-proBNP indicate?
Myocardial stretch
How should cardiac biomarkers be interpreted?
With the history physical exam and other tests
Why can biomarkers cause problems in low-risk patients?
False positives
What blood pressure cuff size should be used?
About 40% of limb circumference
When should blood pressure be measured?
When the patient is calm
What are the main indications for thoracic radiographs?
Cough dyspnea syncope murmur gallop arrhythmia and suspected CHF
What can thoracic radiographs tell you about the heart?
Heart size chamber enlargement and left vs right-sided enlargement
What can thoracic radiographs NOT tell you well?
Myocardial function
Which lateral view is preferred for cardiac cases?
Right lateral
Which lateral view is better for evaluating the right middle lung lobe?
Left lateral
What is the normal VHS in dogs?
What is the normal VHS in cats?
What does VLAS assess?
Left atrial enlargement
What does pulmonary vein enlargement suggest?
Left-sided CHF/increased left heart filling pressure
What does pulmonary artery enlargement suggest?
Pulmonary hypertension
What do enlarged pulmonary arteries AND veins suggest?
Volume overload
What do small pulmonary vessels suggest?
Hypovolemia
What does caudal vena cava enlargement suggest?
Right-sided heart disease
What CVC:A ratio suggests right-sided heart disease?
1.5
What are the 4 major pulmonary patterns?
Interstitial bronchial alveolar and vascular
What is an interstitial pattern associated with?
Early CHF fluid overload interstitial disease fibrosis and metastasis
What does a bronchial pattern look like?
Donuts and tram lines
What is a classic cause of a bronchial pattern in cats?
Feline asthma
What is an alveolar pattern?
Alveoli filled with fluid blood pus or cells
What distribution is typical of bacterial pneumonia?
Cranioventral
What distribution is typical of cardiogenic pulmonary edema?
Perihilar and caudodorsal
What distribution is typical of noncardiogenic pulmonary edema?
Caudodorsal
What is the most common cause of CHF in small-breed dogs?
Chronic mitral valve disease
What is the most common cause of CHF in large-breed dogs?
Dilated cardiomyopathy
What is the most common cause of CHF in cats?
Hypertrophic cardiomyopathy
Do cats commonly cough with CHF?
No
What is an important finding in cats with CHF?
Pleural effusion can occur
What are the 2 major types of cardiac biomarkers?
Leakage markers and functional markers
What is the main cardiac leakage marker?
Cardiac troponin I
What does increased cTnI indicate?
Myocardial injury
Is cTnI specific for cardiac disease?
No
What are functional cardiac biomarkers?
Natriuretic peptides
Where is ANP produced?
Atria
Where is BNP produced?
Ventricles
What is the important clinically measured BNP marker?
NT-proBNP
What is the main use of NT-proBNP?
Distinguishing cardiac from pulmonary disease
What does high NT-proBNP generally suggest in a dyspneic patient?
Cardiac disease/CHF
What does low NT-proBNP generally suggest?
Pulmonary disease
What is a major use of NT-proBNP in Dobermans?
Detection of occult DCM
What can NT-proBNP predict in dogs with mitral disease?
Risk of CHF within 6-12 months
What is the normal feline NT-proBNP cutoff from this lecture?
What feline NT-proBNP level supports CHF?
265 pmol/L
What does echocardiography evaluate?
Cardiac structure and function
What does 2D/B-mode echo show?
Real-time cardiac structures
What does M-mode evaluate?
Motion and measurements including fractional shortening
What does Doppler evaluate?
Blood flow and velocity
What does color Doppler detect?
Regurgitation and abnormal/turbulent flow
What does fractional shortening assess?
LV contractility
What is normal fractional shortening in dogs?
25-45%
What is normal fractional shortening in cats?
35-55%
What does low fractional shortening suggest?
Poor contractility especially DCM
What can high fractional shortening be associated with in cats?
HCM
What does thickened LV wall suggest in cats?
HCM
What does thickened LV wall suggest in dogs?
Subaortic stenosis
Why is left atrial enlargement important?
It supports left-sided CHF and indicates increased risk of CHF
What is pericardial effusion on echo?
Fluid around the heart
What does right-sided chamber collapse with pericardial effusion indicate?
Cardiac tamponade
When is a focused echo useful?
Respiratory distress collapse confusing radiographs murmurs arrhythmias or suspected effusion
What does a Holter monitor detect?
Intermittent or hidden arrhythmias
What breed is classically screened for ARVC with a Holter?
Boxer
What is the key difference between Holter and event monitoring?
Holter is continuous and event is targeted
What test is best for determining the type of heart disease?
Echocardiography
What test is most important for determining if a dog is in CHF?
Thoracic radiographs