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Heart
Hollow muscular organ that lies in central thoracic cavity slightly to the L of midline, between 3 and 5 intercostal spaces, anterior to vertebrae, posterior to sternum & lungs
Pericardium
Fluid filled, loose, double layered sac of elastic connective tissue that encloses the heart
10-50mL of serous fluid (prevents friction)
Surrounds heart and proximal ends of aorta, vena cava, & pulmonary artery
Protects against infection, trauma, & friction
Free pumping motion
Layers of pericardium
Fibrous (outer)
Serous (inner)
Parietal layer lines inside of fibrous pericardium
Visceral layer (epi) lines outside of heart
Pericardial space
Located between visceral & parietal layers. Contains clear fluid released by serous membrane that acts as lubricant to prevent friction during contraction & relaxation of heart
Pericardial effusion
In certain disease states the pericardial sac can fill with fluid
Right side of heart
Low pressure
Receive deoxygenated (venous) blood from body
Pumps to lungs (pulmonary)
Left side of heart
High pressure
Receives oxygenated (arterial) blood from lungs
Pumps to body (systemic)
What are atrial appendages (auricles)?
Blind pouches extending from each atrium that increase atrial surface area. Made up of pectinate muscles.
What are pectinate muscles and their function?
Parallel muscles in the atrial appendages that increase contractility without increasing muscle mass.
Where are the right and left atrial appendages located?
Right: Extends over the aortic root.
Left: Projects alongside the pulmonary artery.
Lining of RA
It is smooth except in the anterior wall and the atrial appendage
What is the interatrial septum (IAS) and what is the fossa ovalis?
IAS separates R & L atria
Fossa ovalis (closed window) is a slight depression that represents the closed foramen ovale (open window)
Right atrium location
on the superior portion of the heart
forms the right lateral cardiac border
posterior and to the right of the RV
mostly anterior to the LA
Which parts of the right atrium (RA) have thin walls, and which parts are more muscular?
The posterior wall is thin where the superior vena cava, inferior vena cava, and coronary sinus enter.
The anterior and inferior walls are more muscular because they contain the right atrial appendage and the tricuspid valve.
What is the torus aorticus?
A bulge on the medial wall of the right atrium formed by the right and noncoronary cusps of the aortic valve.
What vessels drain into the RA?
Superior vena cava (SVC): Drains the upper body and head.
Inferior vena cava (IVC): Drains the abdomen and lower extremities; its opening is guarded by the Eustachian valve, which may have a web-like Chiari network.
Coronary sinus: Drains the myocardium via the coronary veins; its opening is guarded by the Thebesian valve.
Left atrium location
lies superiority and posterior to the other cardiac structures
it is the most posterior portion of the heart.
3 main functions of the LA
LA acts as a reservoir during ventricular systole
contracts to deliver blood to the LV
serves as a conduit during LV filling
Key structural features of LA
The anterior LA is more muscular and contains the LA appendage with pectinate muscles. The rest of the LA is smooth, and the fossa oval is is present but less prominent
LA appendage & LA walls
LA appendage is a common site of thrombus (clot) formation and is best seen on TEE (transthoracic echo). The LA is slightly smaller than the RA but has thicker walls because of higher left sided pressures.
Ventricles
located inferior to atria
thicker walls due to higher pumping pressure
IVS- triangular wall that separates the R and L ventricles
Right Ventricle
receives o2 poor blood from RA during diastole & pumps blood to lungs during systole
RV is the most anterior chamber, located beneath the sternum
Crescent shaped
thinner walls than LV
contains irregular inner surface with trabeculae carneae
How does RV compare to LV in terms of trabeculae?
RV = heavily transected, especially compared to LV
Crista supraventricularis
Thick muscular ride in the RV that seperates the inflow and outflow tracts & arches over the anterior leaflet of the TV
What is the RVOT?
The superior/anterior, smooth, cone shaped portion of the RV called the conus arteriosus (infundibulum) that leads to the PV
Moderator band & function
Muscle in RV that extends from lower IVS to the RV free walk/pap muscle. It carries the RBB of the conduction system and helps prevent RV overexpansion.
Left Ventricle
receives o2 blood from LA during diastole & pumps blood to aorta/body during systole
ellipsoid/cone shaped, usually larger than RV, divider into an o flow & outflow tract
What forms the LVIT?
The MV annulus, mitral leaflets, & chordae from the funnel shaped LVIT
What is LVOT?
Surrounded by anterior mitral leaflets, IVS, & LV free wall & ends at aortic annulus
Why are LV walls thicker than RV walls?
LV walls are 2-3 times thicker because it pumps blood through high resistance systemic circuit
How does LV compare to the RV in muscle mass & trabeculation?
LV contains about 75% of hearts muscle mass & is less trabeculated than RV. The LV & RV have equal chamber volumes.
Valves & function
4 main valves prevent backward (retrograde) blood flow in heart.
Semilunar: AOV & PV
AV: TV & MV
SL valves & function
AOV & PV
located at the outlets of the ventricles. each has 3 fibrous cusps
When do SL valves open & close
They open when ventricular pressure is higher than the great vessels, allowing blood flow to the pulmonary and systemic circulation. They close when vent ventricular pressure drops, preventing blood from flowing back into the ventricles.
AOV location & function
located in LVOT between LV & aorta
allows blood to flow into aorta & prevents backflow into LV
What are the 3 cusps of AOV?
RCC
LCC
NCC
What are the sinuses of Valsalva & why is it important
Pouch like areas behind each aortic cusp. The R & L sinuses give rise to the R & L coronary arteries
Arantius nodules & function
Small nodules at ends of each aortic cusp that support the cusps & help prevent valve leakage
What is the moral aortic valve area?
2-4 cm2
PV location & function
right sided SL valve located in RVOT between the RV & MPA
allows blood flow to lungs & prevents backflow into RV
What are the 3 cusps of the PV?
anterior
right posterior
left posterior
How does PV compare to the AOV?
The PV cusps are slightly thinner than AOV cusps.
Normal valve area: 2-4 cm2
AV valves & location
separate the atria & ventricles
TV (R side)
MV (bicuspid) (L side)
What structures support AV valves?
Supported by the valve annulus, chordae, & pap muscles
Function of AV valves
Inlet valves of the ventricles that prevent blood from flowing backward from the ventricles into atria
TV & location
R AV valve
located between RA & RV.
larger & thinner than MV & sits more apically
3 leaflets of TV
anterior- largest
septal (medial)- attached to IVS
posterior- smallest & attaches to tricuspid annulus (ring)
What supports TV leaflets
3 pap muscles connected by chordae. The chordae attach the leaflets to pap muscles.
Function of TV pap muscles & chordae
During ventricular contraction, the pap muscles pull leaflets together & downward, preventing valve from opening backward
Normal TV area
7-9 cm2
Characteristics of anterior medial mitral leaflet
It is triangular shaped, extends from the posterioromedial LV to the anterolateral LV wall, and is continuous with the posterior aortic root wall
Characteristics of posterior mitral leaflet
It is quadrangular shaped, longer than the anterior leaflet, and surrounds about 2/3 of the mitral valve opening (orifice)