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joint fluid
synovial fluid is also known as ___
mucopolysaccharide; hyaluronic acid
synoviocytes secret ___, a large molecule that produces the viscosity of the fluid
arthritis
damage to joints
arthrocentesis
method of collection
Type I: Noninflammatory
CLASSIFICATION OF ARTHRITIS
ostearthritis
degenerative joint disorder
neutrophils: <30%
Type IIa: Immunologic
CLASSIFICATION OF ARTHRITIS
autoimmune disorders; SLE, RA
neutrophils: >50%
Type IIb: Crystal Induced
CLASSIFICATION OF ARTHRITIS
gout - monosodium urate
pseudogout - calcium pyrophosphate
WBCs: up to 100,000/uL
Type III: Septic
CLASSIFICATION OF ARTHRITIS
infection - S. aureus, S. pyogenes, S. pneumoniae, N. gonorrhoeae
WBCs: 50,000 to 100,000/uL
Type IV: Hemorrhagic
CLASSIFICATION OF ARTHRITIS
trauma
coagulation disorders
heparin overdose
Mucin Clot
VISCOSITY
detects and measures hyaluronic acid; 4-6 cm
acetic acid
VISCOSITY
addition of __ to normal synovial fluid will form a clot surrounded by clear liquid
normal saline
CELL COUNTS
diluting fluid
0.05% hyaluronidase
CELL COUNTS
if extremely viscous
<200/uL
CELL COUNTS
normal count
Monosodium Urate
CRYSTAL IDENTIFICATION
needle shaped, strong bifringent under polarized light
yellow when aligned with slow vibration of compensated polarized light
blue when vertical to slow vibration
elevated serum uric acid levels
Calcium Pyrophosphate Dihydrate
CRYSTAL IDENTIFICATION
rhombic, intracellularly in neutrophil vacuoles
blue when aligned with slow vibration of compensated polarized light
yellow when vertical to slow vibration
enriched chocolate agar
MICROBIOLOGY
for detection of Haemophilus & Neisseria gonorrhoeae
Monosodium urate
CRYSTALS
needle
gout
Calcium Pyrophosphate Dihydrate
CRYSTALS
rhombic
pseudogout
Cholesterol
CRYSTALS
notched-rhombic
extracellular
Corticosteroid
CRYSTALS
flat
injections
Calcium oxalate
CRYSTALS
envelopes
renal dialysis
Calcium phosphate/Apatite
CRYSTALS
small particles; need electron microscopy
osteoarthritis