Fluorescein Staining Patterns

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Last updated 9:52 AM on 6/24/26
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32 Terms

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Superficial Punctate Keratitis (SPK)

Isolated or diffuse dots across a larger area of the cornea. An isolated pattern may be due to a poor contact lens fit or infection, while a diffuse pattern may indicate solution toxicity or an interaction between certain lens/solution combinations or dry eye syndrome.

<p>Isolated or diffuse dots across a larger area of the cornea. An isolated pattern may be due to a poor contact lens fit or infection, while a diffuse pattern may indicate solution toxicity or an interaction between certain lens/solution combinations or dry eye syndrome.</p>
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Superior epithelial arcuate lesion (SEAL)

present parallel to the superior limbus and are due to mechanical chaffing by a contact lens on the superior cornea. The patient is usually asymptomatic.

<p>present parallel to the superior limbus and are due to mechanical chaffing by a contact lens on the superior cornea. The patient is usually asymptomatic.</p>
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Inferior arcuate staining

presents parallel to the inferior limbus and is due to dehydrated contact lenses associated with insufficient post-lens tear film. Patients may have complaints of mild discomfort.

<p>presents parallel to the inferior limbus and is due to dehydrated contact lenses associated with insufficient post-lens tear film. Patients may have complaints of mild discomfort.</p>
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Three and nine o'clock staining

presents parallel to the nasal and temporal limbus and is due to contact lens associated dry eye. Patients may experience mild discomfort.

<p>presents parallel to the nasal and temporal limbus and is due to contact lens associated dry eye. Patients may experience mild discomfort.</p>
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Dimple veil staining

not true staining, but rather pooling of the dye into corneal indention caused by trapped air bubbles under a poorly fitting rigid gas permeable contact lens. It presents as sharply demarcated, circular patterns of stain on the cornea.

<p>not true staining, but rather pooling of the dye into corneal indention caused by trapped air bubbles under a poorly fitting rigid gas permeable contact lens. It presents as sharply demarcated, circular patterns of stain on the cornea.</p>
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Foreign body staining

or mechanical trauma can present in various ways, such as a zigzag-shaped abrasion or as the outline shape of an embedded foreign body.

<p>or mechanical trauma can present in various ways, such as a zigzag-shaped abrasion or as the outline shape of an embedded foreign body.</p>
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Epithelial Basement Membrane Dystrophy (EBMD)

raised dots, maps and fingerprints and results in negative staining. The elevations of the ocular surface, result in an immediate tear film break-up over the corresponding area. Patients are usually asymptomatic unless the dots, maps and fingerprints erupt, at which time they will stain positively and become symptomatic

<p>raised dots, maps and fingerprints and results in negative staining. The elevations of the ocular surface, result in an immediate tear film break-up over the corresponding area. Patients are usually asymptomatic unless the dots, maps and fingerprints erupt, at which time they will stain positively and become symptomatic</p>
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Herpetic Keratitis

Dendritic ulcers are associated with the herpes simplex virus (HSV). The edges may be slightly elevated due to swollen epithelial cells.

<p>Dendritic ulcers are associated with the herpes simplex virus (HSV). The edges may be slightly elevated due to swollen epithelial cells.</p>
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Use fluorescein to stain the:

cornea

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Use lissamine green to stain the:

conjunctiva, even in your asymptomatic patients.

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Alignment fit

Back surface of lens matches the curvature of the cornea

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Clearance

(STEEP) There is space between the lens and the cornea

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Touch

(FLAT) The lens is close to the cornea, compared to another part of the lens

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Apical

-Central portion of FP

-Area under optic zone

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Mid-peripheral

-Area under the intermediate curves

-Determines lens positioning and movement patterns

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Peripheral

-Area under peripheral curves

-Determines tear exchange

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Static pattern

-FP when lens is centered on the cornea

-If lens de-centers, use PT lids to manually center

-Gives true apical relationship

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Dynamic pattern

-FP when lens is in normal resting position

-May be different than static pattern

-pattern not as flat as when centered because peripheral cornea is flatter.

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Apical Alignment (AA)

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Apical Clearance

Steep fit

<p>Steep fit</p>
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Apical Touch

Flat fit

<p>Flat fit</p>
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mid-peripheral alignment

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mid-peripheral touch

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peripheral clearance- minimal/none

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peripheral clearance- moderate/medium

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peripheral clearance- High/excessive

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With the rule (WTR)

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Against the rule (ATR)

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With the rule corneas:

-Superior or inferior position

-good for lens alignment, but poor for inferior

-Steeper fits tend to center better

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Against the rule corneas:

-Temporal or nasal position

-poor comfort when de-centered laterally

-Steeper fits tend to center better

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Base curve radius: too steep

Green appearance centrally

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Base curve radius: too flat

Black appearance centrally