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Monomers
small molecular building blocks of polymers
Endothermic Reaction
A reaction that ABSORBS energy in the form of heat
Hydrolysis
a chemical reaction that adds water to a macromolecule in order to break its covalent bond; key component in digestion
The creation of macromolecules is what kind of reaction?
Endothermic reaction called dehydration
The breakdown of macromolecules is what kind of reaction?
Exothermic reaction called hydrolysis
4 Types of Macromolecules
carbohydrates, lipids, proteins, nucleic acids
Macromolecules are also known as
biopolymers
Simplest unit of a carbohydrate
monosaccharide
At the molecular level, carbohydrates contain
Carbon, hydrogen, and oxygen
Glucose
A very common carbohydrate monomer that exists as a hexose (meaning it has 6 carbons in it).
Carbohydrate monomers tend to end in
-ose
Carbohydrate functions in living systems
1. storage
2. structure
3. communication/recognition
Plants use carbohydrates in the form of
cellulose
chitin
carbohydrate used by fungi to add structure to their cell wall and by insects/anthropods in their exoskeleton
Glycoprotein
A protein with one or more carbohydrates covalently attached to it, used by the human body for cellular recognition. Oligosaccharide with amino acids attached that attaches to a cell's lipid membrane in cellular recognition; antibody, immunoglobulin
Carbohydrate stored in the liver
glycogen
Smallest unit of a lipid
fatty acid
On a molecular level, lipids contain a lot of
hydrogen and carbon
Lipids do not mix with water, meaning they are
hydrophobic
Lipids have 2 important functions
1. Storing energy
2. Providing structure
Adipose Tissue
Connective tissue in the body that stores fat.
Phospholipids
Used by cells, particularly in cell membranes, to provide structure
This lipid bilayer has a hydrophilic phosphate group that points towards the aqueous environment:
phospholipid bilayer
Simplest unit of a protein
amino acid
All proteins contain
C, H, O and N (Nitrogen)
amine group (NH2) and carboxyl group (COOH)
Functions of proteins in the body
1. Provide structure
2. Provide immunity
3. Provide transport
4. Increase reaction rate (enzymes).
Amino acids are joined by what bond?
Peptide
Hydrophobic proteins have a function of providing ________ & are found where?
structure; keratin (hair and nails), and collagen (skin)
What is the function of membrane proteins?
-transport substances across the plasma membrane as protein channels and carrier proteins
-structure
-body wide communication (immunity)
Hydrophilic proteins in the body are known as
Globular proteins
Examples of globular (hydrophilic proteins)
1. Enzymes
2. Antibodies
3. Hemoglobin
Enzyme
Protein that increases reaction rate in the body
Fibrous, hydrophobic protein that is the main structural tissue in the body
Collagen
Protein with hydrophobic ends that transport material in and out of the cell that is used in cellular communication
Membrane protein
Simplest unit of nucleic acids
nucleotide
Every monomer of nucleic acid contain 3 things:
1. sugar
2. phosphate group
3. nitrogen containing base
2 Types of nucleic acids:
1. DNA (deoxyribonucleic acid)
2. RNA (ribonucleic acid)
DNA contains the sugar ____________, while RNA contains the sugar ___________.
deoxyribose; ribose
What is the function of messenger RNA?
Carries information specifying amino acid sequences of proteins from DNA to ribosomes- translates the DNA's instructions to make proteins
RNA carries information from the nucleus to the _______ where proteins are made
ribosome
______ in DNA and RNA can lead to error in proteins.
Mutations
Centromere
Area where the chromatids of a chromosome are attached
Chromatid
one of two identical "sister" parts of a duplicated chromosome joined at the centromere containing DNA + Protein.
Gene
Group of DNA base pairs that encode a protein
DNA
Deoxyribonucleic acid that has a double helix structure, deoxyribose sugar backbone, phosphate group, and nitrogenous bases
Purines
Bases with a double-ring structure.
Adenine and Guanine
Pyrimidines
cytosine and thymine (uracil in RNA)
What is the bond between nitrogenous bases?
hydrogen bonds
Allele
Different types or versions of a gene
Gene
Section of DNA that encodes a protein
Genotype versus phenotype
Genotype
Genetic makeup a person inherits
Phenotype
Characteristic or trait the person eventually has
Observed physically
Which organelle makes a ribosome?
Nucleolus
What makes the mitotic spindle?
microtubules
Which macromolecule will always contain a nitrogen
Protein (NH2)
Which nitrogenous base does uracil replace in DNA?
thymine
Which type of bond connects monomers in carbohydrates and lipids?
Covalent (carbohydrates)
How are carbohydrates stored in the liver?
as glycogen
Which organelle contains digestive enzymes?
Lysosome
Muscle cells contain a lot of which organelle?
Mitochondrion
A cell that secretes chemicals contain higher levels of what organelle?
Golgi Apparatus
Adenine pairs with ______ in DNA, and with ______ in RNA
Thymine; uracil
Codon
three-nucleotide sequence on messenger RNA that codes for a single amino acid
How many amino acids exist?
20
Process of creating mRNA from DNa
transcription
Process of encoding proteins
Translation
Independent Assortment
the random distribution of genes into gametes during meiosis
Monohybrid Cross
A cross between organisms examining one pair of traits. Expected ratio if Dominant/Recessive= 3:1
Mendelian Inheritance
Inheritance of genes which follow predictive ratios of dominant/recessive alleles.
3:1 Monohybrid
9:3:3:1 Dihybrid
Combination Inheritance
Different alleles expressed at the same time (AB)
Incomplete Dominance
Cases in which one allele is not completely dominant over another, in which the heterozygous organism expresses a third trait
Polygenic Inheritance
An additive effect of two or more genes on a single phenotypic character.
Dehydration Synthesis
A chemical reaction in which two molecules covalently bond to each other with the removal of a water molecule (endothermic)- how macromolecules form
Carbohydrates that store energy
Glycogen (humans) Amylopectin and Amylose (plants)
Carbohydrates used in cellular communication
Glycoprotein (immunity) & Glycolipids (cell membrane)
How are hydrophobic proteins used in the body?
Provide structure; keratin & collagen
Which nucleic acid regulates protein expression?
RNA
Which type of reaction describes the breakdown of macromolecules?
Hydrolysis
The 2 major classes of proteins are
Hormones and Enzymes
What is the ratio of carbon to hydrogen to oxygen in carbohydrates?
1:2:1
When lipids are broken down, they release
Energy
Polypeptides
a polymer of amino acids joined together by peptide bonds.
Which type of bond between the complementary bases of DNA stabilizes the double helix structure?
Hydrogen bond
RNA is unstable under ____ conditions.
alkaline
The sugar found in DNA is more _________ than that of RNA's.
reduced
What characteristic of an element determines its specific isotope?
Neutron
3 Primary types of chemical bonds:
1. Covalent
2. Ionic
3. Polar
What does the pH scale measure?
the concentration of hydrogen ions in a solution
What does the rate of a chemical reaction depend on?