INFECTIOUS MONONUCLEOSIS

INFECTIOUS MONONUCLEOSIS IS ALSO KNOWN AS THE?

KISSING DISEASE/GLANDULAR FEVER

CAUSATIVE AGENT OF INFECTIOUS MONONUCLEOSIS IS THE?

DNA VIRUS, EPSTEIN BARR VIRUS

EPSTEIN BARR VIRUS INFECTS WHAT CELL?

B LYMPHOCYTES

THESE ARE ENLARGED LYMPHOCYTES AFFECTED BY EBC WITH A CHARACTERISTICS ATYPICAL NUCLEI

DOWNEY CELLS

DOWNEY CELLS ARE ALSO KNOWN AS?

ATYPICAL LYMPHOCYES/REACTIVE LYMPHOCYTES

THIS CHARACTERISTICS IS NOT EXCLUSIVE TO IM BUT IT IS A DIAGNOSTIC FEATURE OF IM IN PERIPHERAL CIRCULATION

DOWNEY CELLS

TRUE OR FALSE. EBV INFECTION IS MOST COMMON DURING ADOLESCENCE AND EARLY ADULTHOOD (AGES 15-25). THE COMMON TARGET ARE MALE YOUNG ADULTS.

A. BOTH ARE CORRECT

B. BOTH ARE INCORRECT

C. 1ST STATEMENT IS TRUE; 2ND STATEMENT IS FALSE

D. 1ST STATEMENT IS FALSE; 2ND STATEMENT IS TRUE

C

WHAT ARE THE SYMPTOMS OF INFECTIOUS MONONUCLEOSIS?

FEVER, FATIGUE, SORE THROAT, SWOLLEN LYMPH GLANDS

THIS IS CONDUCTED FOR INFECTIOUS MONONUCLEOSIS DIAGNOSIS

EXPERIMENT OF FORSSMAN

THIS IS WHEN GUINEA PIG CELLS ARE INJECTED INTO RABBITS ANTIBODY FORMATION

EXPERIMENT OF FORSSMAN

IN THE EXPERIMENT OF FORSSMAN, ASIDE FROM GUINEA PIG, THE RABBIT’S ANTIBODY ALSO REACTS WITH?

SHEEP CELLS

ANY SUBSTANCES THAT STIMULATED THE FORMATION OF SHEEP HEMOLYSIN (ANTI-SHEEP CELLS)

FORSSMAN ANTIGEN

ANTIBODIES PRODUCED BY UNRELATED SPECIES WHICH CAN CROSS-REACT WITH THE SAME ANTIGEN

HETEROPHIL ANTIBODIES

IN HETEROPHIL ANTIBODIES IN IM, IT REACTS WITH SHEEP CELLS, OX, AND HORSE CELLS BUT NOT IN?

GUINEA PIG CELLS

IN HETEROPHIL ANTIBODIES IN FORSSMAN, IT REACTS WITH GUINEA PIG CELLS, HORSE, SHEEP CELLS BUT NOT WITH?

BEEF CELLS

IN ___, IT REACTS WITH SHEEP, OX, HORSE, AND GUINEA PIG CELLS

HETEROPHIL ANTIBODIES IN SERUM SICKNESS

ANTIBODIES IN THIS IS USED FOR THE CONTROL OR VALIDATION OF RESULT IN IM IN FORSSMAN

HETEROPHIL ANTIBODIES IN SERUM SICKNESS

TESTS FOR INFECTIOUS MONONUCLEOSIS

SCREENING AND DIFFERENTIAL

WHAT IS THE PRINCIPLE OF PAUL BUNNEL TEST?

HEMAGGLUTINATION

THIS IS A SCREENING AND QUALITATIVE TEST FOR INFECTIOUS MONONUCLEOSIS

PAUL BUNNEL TEST

INCAPABLE OF DETERMINING SPECIFICITY AND IS ONLY INDICATIVE OF THE PRESENCE OR ABSENCE OF HETEROPHIL ANTIBODIES

PAUL BUNNEL TEST

WHAT IS THE REAGENT ANTIGEN FOR PAUL BUNNEL TEST

2% SUSPENSION OF SHEEP RBC

ANTIBODY FOR PAUL BUNNEL TEST

HETEROPHIL ANTIBODY IN PATIENT’S SERUM

IF THE PATIENT IS POSITIVE FOR PAUL BUNNEL TEST, WHAT IS THE NEXT STEP?

A. REPORT AS POSITIVE FOR IM

B. IDENTIFY THE HETEROPHIL AB PRESENT

C. REDO THE TEST

D. REPORT AS FALSE POSITIVE

B

WHAT IS THE PRINCIPLE FOR DAVIDSON DIFFERENTIAL TEST?

ABSORPTION-HEMAGGLUTINATION

A DIFFERENTIAL TEST WITH A TWO STEP PROCEDURE

DAVIDSON DIFFERENTIAL TEST

FIRST STEP FOR DAVIDSON DIFFERENTIAL TEST

ABSORPTION STEP

INDICATOR CELLS FOR DAVIDSON DIFFERENTIAL TEST

SHEEP RBCS

TRUE OR FALSE. IN STEP 1 OF DAVIDSON DIFFERENTIAL TEST, IF THE ABSORPTION TEST IS POSITIVE, THE AB TITER IS DECREASED—IF THE ABSORPTION TEST IS NEGATIVE, THE AB TITER REMAINS HIGH

TRUE

PRINCIPLE OF THE MONOSPOT TEST

ABSORPTION HEMAGGLUTINATION

INDICATOR CELLS IN MONOSPOT TEST

HORSE RBCS

PRINCIPLE FOR RAPID DIFFERENTIAL SLIDE TEST USING PAPAIN-TREATED SHEEP RBCS

HEMAGGLUTINATION

IN RAPID DIFFERENTIAL SLIDE TEST, THIS INACTIVATES THE RECEPTOR FOR HETEROPHIL AB FOUND ON RED BLOOD CELL SURFACE, ESPECIALLY SHEEP RBC TO IM, HOWEVER, IT CANNOT INACTIVE OTHER ABS SUCH AS SICKNESS SERUM

PAPAIN

REAGENT USED IN RAPID DIFFERENTIAL SLIDE TEST

SHEEP RBC