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Flashcards on the Muscular System
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Functions of Skeletal Muscle
Support & movement, provides protection, gives body form, communication, temperature regulation
Skeletal muscles
≈ 650-700 named; more still discovered
Tendons
Cord-like; attach muscle to bone
Aponeuroses
Flattened tendon sheets; attach muscle to bone or muscle to muscle
Skeletal Muscle Tissue
Linear cells, multinucleated, striations, voluntary & strong; attaches bone to bone; provides movement
Cardiac Muscle Tissue
Only in heart; highly branched fibers; mono-nucleated, faint striations, involuntary
Intercalated discs
Spot desmosomes = strong cell-to-cell links; Gap junctions = shared cytoplasm → functional syncytium
Smooth Muscle Tissue
No striations, single nucleus, propeller-shaped cells; woven like fabric; lines hollow organs
Motor Unit
All muscle cells responding to the same nerve fiber
Synaptic vesicles
Store acetylcholine (ACh)
Synaptic cleft
Gap where ACh diffuses
Sarcolemma
Folded for ↑surface; houses ACh receptors
Motor end plate
Specialized postsynaptic membrane
AChE (acetylcholinesterase)
Enzyme breaking down ACh
Depolarization
Voltage change when Na enters
Creatine-P Key Reaction
Creatine P → creatine + P + energy = ADP → ATP
Aerobic Resp. Key Reaction
Glucose → ATP + CO₂ (or Glycogen → Glucose → …)
Myoglobin
O₂-storage pigment (red-brown)
Anaerobic Key Reaction
Glucose → Pyruvic acid → Lactic acid
Fast-Twitch (White) Muscle Fibers
No myoglobin, few mitochondria → low ATP; contracts & fatigues quickly
Slow-Twitch (Red-brown) Muscle Fibers
Myoglobin-rich, many mitochondria; contracts slowly, high endurance
Threshold
Minimum stimulus
Recruitment
Stronger stimulus → more units
Graded response
Force is proportional to units engaged
All-or-None
Each fiber fires completely once threshold reached
Absolute Refractory Period
No response
Relative Refractory Period
Needs supra-threshold stimulus
Tetanus
Summation of twitches
Multiple motor-unit summation
↑frequency + ↑strength = max force
Asynchronous activation
Units rotate for sustained hold
Rigor Mortis
ATP depleted post-mortem → stiffness, resolves after decomposition
Latent Phase
Stimulus, no shortening
Contraction Phase
Fiber shortens
Relaxation Phase
Returns to length
Refractory Phase
Unresponsive
Isotonic Contraction
Muscle shortens, constant load
Isometric Contraction
Length constant, tension rises
Tetanus
Sustained contraction
Muscle tone
Baseline partial contraction
Prime mover (agonist)
Main muscle for movement
Antagonist
Opposes agonist
Synergist
Assists prime mover
Fixator
Stabilizes origin
Origin
Immovable point
Insertion
Movable point (pulled toward origin)
Action
Movement produced (muscle can only move insertion toward origin)
Muscle Fiber
A single muscle cell; specialized for contraction, poor at healing.
Motor Unit
A single motor neuron and all the muscle fibers it stimulates.
Tendon
A cord-like structure that connects muscle to bone.
Aponeurosis
A flat sheet-like tendon that connects muscle to bone or muscle to muscle.
Origin
The fixed, immovable attachment point of a muscle.
Insertion
The movable attachment point of a muscle, pulled toward the origin during contraction.
Action
The movement produced when the muscle contracts and the insertion moves toward the origin.
Skeletal Muscle
Voluntary muscle with striations and multiple nuclei; responsible for body movement and posture.
Cardiac Muscle
Involuntary muscle found only in the heart; branched fibers with faint striations and a single nucleus.
Smooth Muscle
Involuntary muscle with no striations and a single nucleus; found in walls of hollow organs.
Intercalated Disc
A structure between cardiac muscle cells that contains desmosomes and gap junctions for strength and communication.
Functional Syncytium
A condition in which cardiac muscle cells contract together as a unit due to communication through gap junctions.
Sarcolemma
The plasma membrane of a muscle cell; folded to increase surface area for receptors.
Synaptic Vesicle
A small sac in the axon terminal that contains neurotransmitters like acetylcholine (ACh).
Synaptic Cleft
The small space between the nerve ending and muscle membrane where neurotransmitters are released.
Acetylcholine (ACh)
A neurotransmitter released by nerve cells that triggers muscle contraction.
Acetylcholinesterase (AChE)
The enzyme that breaks down acetylcholine in the synaptic cleft.
Depolarization
A change in electrical charge across a membrane that initiates an action potential.
Creatine Phosphate
A high-energy compound that quickly regenerates ATP in muscle cells.
Myoglobin
An oxygen-binding protein in muscle cells; gives muscle its red-brown color.
Aerobic Respiration
ATP production using glucose and oxygen; slower but efficient.
Anaerobic Respiration
ATP production without oxygen, resulting in lactic acid build-up.
Oxygen Debt
The amount of oxygen required to restore the muscle to its resting state after activity.
Fast-Twitch Fiber
Muscle fibers that contract quickly with little endurance; few mitochondria, no myoglobin.
Slow-Twitch Fiber
Muscle fibers that contract slowly but are fatigue-resistant; rich in mitochondria and myoglobin.
Threshold Stimulus
The minimum stimulus strength needed to cause a muscle fiber to contract.
All-or-None Response
Once threshold is reached, a muscle fiber will contract fully.
Recruitment
The process of increasing the number of active motor units to lift a heavier load.
Graded Response
The varying degree of muscle contraction based on stimulus strength.
Twitch
A single brief contraction followed by relaxation.
Summation
Repeated stimulation of a muscle before it fully relaxes, leading to a stronger contraction.
Tetanus
A sustained muscle contraction from rapid stimulation.
Complete Tetanus
No relaxation occurs between contractions.
Incomplete Tetanus
Partial relaxation occurs between contractions.
Refractory Period
The time during which a muscle fiber cannot respond to a second stimulus.
Absolute Refractory Period
The muscle fiber absolutely cannot respond.
Relative Refractory Period
The muscle fiber can respond to a stronger-than- normal stimulus.
Asynchronous Motor Unit Activation
Switching between motor units during sustained contraction to prevent fatigue.
Rigor Mortis
Stiffening of muscles after death due to lack of ATP.
Isotonic Contraction
Muscle tension stays the same, and the muscle shortens.
Isometric Contraction
Muscle length stays the same, but tension increases.
Muscle Tone
A continuous state of partial contraction in resting muscles.
Prime Mover (Agonist)
The main muscle responsible for a specific movement.
Antagonist
The muscle that opposes the prime mover.
Synergist
A muscle that assists the prime mover.
Fixator
A muscle that stabilizes the origin of the prime mover.