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two components of neuron doctrine
brain cells work independently
neurons communicate across gaps (synapses)
glial cells function
provide support + nutrition to brain
mitochondria provides cells with
energy
nucleus contains
chromosomes
ribosome function
in the ribosome, genetic information is translated produce proteins
dendrites/….. zone
dendrites/ input zone (receives information)
soma/….. zone
soma/ integration zone (neuron determines whether to send signal or not)
axon/…. zone
axon/ conduction zone (carriers electrical signal)
axon terminals/….. zone
axon terminals/ output zone (transmit neuronal activity across synapse)
axon split into multiple branches
axon collaterals
multipolar neuron
many dendrites + single axon
bipolar neuron
one dendrite on one end + one axon on other end
unipolar neuron
input zone (like dendrites) + output zone (transmit sensory information into spinal cord)
interneurons
receive info then pass along to next neuron otw to brain
arborization
tree-branch-like arrangement of dendrites
presynaptic
area of synapse where neurotransmitter released
postsynaptic
area of synapse where neurotransmitter received
parts of synapse
presynaptic membrane + synaptic cleft + postsynaptic membrane
autoradiograpahy
after an animal brain slice is injected with radiative drugs, scientists expose the brain slice to a film camera to see where radioactive substance has concentrated— allow scientists to map brain
immunohistochemistry
involves creating colorful antibodies that bond to select proteins of interest, by injecting antibodies into neuron, protein distributions can be found
in situ hybridization
labelled nucleic acids used to find distribution of specific proteins
histology
study of tissue composition
nissan stain
reveals cell bodies by staining rna
golgi stain
fills small proportionof nuerons with dense dark products
tract tracer
compound used to identify routes and connectivity of neurons
receptor
binds/ reacts to neurotransmitters/ hormones
neuroplasticity
nervous system’s ability to change in response to environment
motor proteins
attaches to vesicle and moves them around
axonal transport go in which direction
both directions
anterograde transport
moves materials towards axon terminal
retrograde transport
moves material to cell body for recycing
what type of axonal transport is fast?
when electrical signal travels outside of axon it is a rapid transmission
astrocyte
glial cell type- star shaped, form sucker-like ends on blood vessels to help neurons get more blood supply when active
microglial cells
glial cell type- remove cell debris from injured/dead cells
oligodendrocytes
forms myelin in CNS
nodes of ranvier
gaps in myelin sheath where axon is exposed
edema
swelling of tissue
schwann cell
forms myelin in PNS
myelin
fatty insulation around axon, improves speed of conduction
multiple scelerosis
widespread degeneration of myelin
gross neuroanatomy
“ew gross” anatomical features visible with eye
what is a nerve?
collection of axons bundled together outside the CNS
motor nerve
transmit info from spinal cord to body
sensory nerve
conveys information from body to spinal cord and brain
somatic nervous system
nerves connecting brain and large muscles
autonomic nervous system
nerves connecting brain and viscera (internal organs)
dorsal root
branch of spinal nerve, carries sensory info from pns to spinal cord
ventral root
branch of spinal nerve, carries messages from spinal cord to pns
preganglionic neurons
central neurons innervate ganglia
postganglionic neurons
ganglionic neurons innervate the body
autonomic nervous system three divisions
-sympathetic nervous system
-parasympathetic nervous system
-enteric nervous system
neurons that support autonomic functions
autonomic ganglia
ganglia
collection of nerve cell bodies located outside CNS/ in PNS
sympathetic nervous system
middle spine (thoracic + lumbar)
parts of spine
Cervical, Thoracic, Lumbar, Sacral, Coccygeal
spinal segment chunks
8, 12,5,5,1
parts of spine + segment amount/nerve amount
cervical (8 nerves, 7 vertebrae), thoracic (12), lumbar (5), sacral (5), coccygeal (1)
parasympathetic nervous system definition and location
“rest and digest”, originates in brainstem and sacral spinal cord (para- around sympathetic nervous system)
sympathetic system hormone
norepinephrine (noradrenaline)
parasympathetic system hormone
acetylecholine
enteric nervous system
local network of sensory + motor neurons that regulate gut, under CNS control
gyri
raise ridge/ bumps on brain
sulci
shallow grooves on surface of brain
fissures
deep grooves in brain
sylvian fissure also known as
lateral sulcus
cerebral hemispheres
right and left halves of brain
sylvian fissure
demarcates where temporal lobe is
central sulcus
divides frontal and parietal lobes
sagittal plane
divides into left/right
coronal plane
divides into front/back
horizontal plane
divides into top/bottom
ipsilateral
same side of body
contralateral
opposite side of body
proximal
towards the center
distal
towards the limb
afferent
carries info to region of interest
efferent
carries info away from region of interest
postcentral gyrus
strip of parietal cortex directly behind central sulcus, receives somatosensory information from whole body
precentral gyrus
strip of frontal cortex, crucial for motor control
gray matter
no myelin, processes information/ thoughts
white matter
contains axons wrapped in myelin, transmits signals between brain and body
corpus callosum
thick bundle of nerve fibers that connect left and right hemispheres