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These flashcards cover key terms and definitions related to the mechanics of breathing, focusing on the physiology and functions of the respiratory system.
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Alveoli
Small air sacs in the lungs where gas exchange occurs.
Surfactant
A lipoprotein that lowers surface tension and stabilizes alveoli, reduces the work of breathing
Pleural fluid
Fluid that reduces friction and connects the lungs to the chest wall. helps sliding of two surfaces and reduces friction. helps maintain lung volume
Tidal Volume (TV)
The amount of air inhaled or exhaled during normal respiration.
Inspiratory Reserve Volume (IRV)
The maximum amount of additional air that can be inhaled after a normal inhalation.
Expiratory Reserve Volume (ERV)
The maximum amount of additional air that can be exhaled after a normal exhalation.
Residual Volume (RV)
The amount of air remaining in the lungs after a forced exhalation. cannot be measure by spirometry
Vital Capacity (VC)
The maximum amount of air that can be exhaled after a maximum inhalation.
IRV + TV + ERV
Total Lung Capacity (TLC)
The total volume of air in the lungs after maximal inhalation.
IRV + TV + ERV + RV
Forced Vital Capacity (FVC)
The total volume of air that can be forcefully exhaled after full inhalation.
Alveolar ventilation (QA)
The flow of fresh air that reaches the alveoli and participates in gas exchange.
Qa = Ve (respiration rate) x (Vt - tidal volume - Vd(anatomic dead space) )
Respiratory exchange ratio (R)
The ratio of CO2 produced to O2 consumed during metabolism.
R = QCO2/QO2
Henry’s Law
Relates the concentration of a gas in liquid to its partial pressure.
[A] ( concentration of dissolved gas) = Alpha(a) (solubility of gas) x Pa (partial pressure of gas)
Dead space
The part of the respiratory system where gas exchange does not occur.
Bronchodilation
Widening of the bronchi, allowing for increased airflow.
Bronchoconstriction
Narrowing of the bronchi, which can reduce airflow.
Respiration rate (RR)
The number of breaths taken per minute.
Law of Laplace
A principle that describes the relationship between pressure, surface tension, and radius in alveoli, influencing their stability and inflation.
P (pressure) = 2 y( or T surface tension)/ r (radius)
Functional residual capacity (FRC)
The volume of air remaining in the lungs after a passive exhalation, which includes the residual volume and expiratory reserve volume.
RV + ERV
Pulmonary Ventilation
rate at which air moves out of lungs. increases 15 fold during exercise
Qv = RR x TV
Pulmonary fibrosis
stiff lungs
Reynolds number
predicts laminar or turbulent flow
Re = 2aV(average velocity)p(density of air)/n(viscosity) or 2aQv/A(area)n
above 2500 is turbulent and below 2000 is laminar
BTPS to STPD conversion
Vbtps = 1.2104 Vstpd