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Flashcards for key concepts in transcription and translation processes of gene expression.
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Chromatin
Loose DNA that is easily read.
Chromosomes
Tight DNA that is good for traveling.
Human Genome
Contains 20,000-25,000 genes.
Transcription
The process that occurs first, starting with DNA and ending in RNA.
RNA Polymerase
Enzyme that unzips, reads, and builds single-stranded mRNA.
Nucleus
The part of eukaryotic cells where transcription occurs.
Template strand
The DNA strand running from 3’ to 5’ used to make RNA.
Promotor regions
DNA sequences that indicate where RNA Polymerase should begin transcription.
Terminator regions
DNA sequences that indicate where transcription should stop.
Spliceosomes
Molecular machines that cut out introns and leave exons in mRNA.
5’ cap
A protective feature added to the 5’ end of mRNA.
Translation
The second step in gene expression, occurring in the cytoplasm.
Codons
Three letter sequences in mRNA that are read during translation.
Ribosomes
Cellular structures needed for translation of mRNA into proteins.
Start codon
The first codon (AUG) that ribosomes look for to begin translation.
tRNA
Transfer RNA that brings the correct amino acid during translation.
STOP codon
The codon that signals the end of translation.
Primary structure
The sequence of amino acids that form a protein.
Tertiary structure
The three-dimensional shape of a fully folded protein.
Quaternary structure
The complex formed when multiple polypeptide chains come together in a protein.