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Define Spatial Vision
The ability of visual system to detect and resolve stimuli of various Sizes & Contrasts
Absolute luminance is more or less important in spatial vision than Relative luminance?
Less important, because because luminance levels vary greatly in the environment but relative luminance (contrast) for visual stimuli do not
The visual system is evolved to do what?
Detect and recognize objects from patterns of light
Provide an example of clinical application
VA measurements
What is visual acuity?
The smallest detail that can be resolved & recognized
Define Contrast Sensitivity
psychophysical measure used to assess the sensitivity if the visual system to spatial luminance changes of various spatial frequencies
a more comprehensive test of spatial vision
How is contrast sensitivity measured?
finding the lowest contrast needed to see light/dark grating of varied fineness or spatial frequency
VA is one point of
contrast sensitivity function
Define Luminance and its unit
the physical amount of light emitted by a source or reflected from an illuminated object
Define brightness
the perception of a luminous object by the human visual system
What affects brightness perception
Adaptation, aftereffects, the presence or absence of other objects in the visual field
Define Contrast
the difference in luminance between an object Lmax and its background Lmin
where the object is typically brighter than the background
Define Modulation?
The term for contrast of a repeating pattern, commonly referred to as a grating
where it is not apparent which part of the pattern is the object and which is the background
How is modulation (contrast) calculated?
the ratio of the difference of the luminance to the sum of the luminance
M=(Lmax-Lmin)/(Lmax+Lmin)
How can modulation be alternately expressed?
by the mathematically equivalent ratio of the difference between maximal and average luminance to the average luminance's
M=(Lmax-Lavg)/Lavg
where Lavg=(Lmax+Lmin)/2
Define Contrast Threshold
the least amount of contrast that can be seen in a chart, expressed at a %
(weber contrast)
Define log contrast sensitivity
converts the contrast sensitivity values to a linear scale, more suitable for comparisons between the levels of contrast sensitivity,
The smaller the log CS value=the poorer the pt CS
Define Contrast sensitivity
The reciprocal of contrast threshold
How do you calculate contrast threshold from log contrast sensitivity and vice versa?
CT=1/CS
CS=1/CT
The log contrast sensitivity score of a patient in Pelli Robson Chart is 1.65. What is the contrast sensitivity and contrast threshold?
10^1.65=CS
CT=1/CS
What is spatial frequency?
refers to the number of light/dark cycles per degree
Name and describe the 3 types of contrast
Weber contrast for letter stimuli
Michelson contrast for Gratings
RMS contrast for natural stimuli
What is Weber contrast?
(luminance of background-luminance of target)/luminance of background
commonly used in cases where the small target/features are present on a large uniform background
*preferred for letter stimuli
What is Michelson contrast?
(Lmax-Lmin)/(Lmax+Lmin)
*preferred for gratings
What does RMS (root mean square) contrast not depend on?
Does not depend on the angular frequency content or the spatial distribution of contrast of the image
What is RMS?
the standard deviation of the Pixel intensities
Weber contrast values are about _________ the Michelson values
twice
What is a sine wave?
mathematical curve that describes a smooth repetitive oscillation
characterized by their spatial frequency, contrast and phase
Why do we use sine wave?
They maintain shape even after degradation and only change in contrast and phase
Sine wave gratings are most useful for?
studying thresholds of the visual system than any other waveform because it is composed of a SINGLE spatial frequency
What are the elements used to describe sine-wave grating?
frequency, contrast, phase, orientation
What does phase refer to?
the position of a sine wave grating with respect to another sine wave grating
What is orientation?
describes the angle made by grating with respect to a reference (such as the horizontal, vertical)
Our visual system is believed to act as what?
a Fourier analyzer, the visual system is thought to deconstruct the retinal image into its spatial frequency components
What is Fourier Transformation?
A mathematical process that transforms a signal (function) from the Spatial domain to frequency domain
Image processing, signal detection
Why did we learn about Fourier transformation in this topic?
In Fourier Analysis, Sine waves of the proper frequency, contrast, phase and orientation can be used to construct complex stimuli
Square wave gratings
luminance profiles show abrupt changes between bright and dark bars "step" changes in luminance
How do you construct a square wave?
by adding since waves together
Sine wave that is the same frequency as square wave is referred to as what?
Fundamental
Higher frequency sine waves are referred to as
Harmonics
What does 3rd harmonics mean?
it has 3 times the frequency of the fundamental and 1/3rd of its contrast
What does 5th harmonic mean?
5 times the frequency of the fundamental and 1/5th of its contrast
Addition of the fundamental sine wave and the odd numbered harminonic (3 and 5) produces a....
square wave
Adding all the ODD numbered harmonics to the fundamental will produce
perfect square wave
Fourier analysis can determine
the component sine waves & contrast of complex waveforms
Fourier Synthesis
can construct square wave grating using the component sine wave & contrasts
What is MTF?
The ability of an optical system to produce an accurate image of an object
modulation transfer function
MTF=image contrast/object contrast
Why wont an image never be perfect
due to diffraction, chromatic and monochromatic aberrations, focus, and power errors
How does MTF change for high and low spatial frequency?
for low spatial frequencies the image blur is hardly noticeable
for high spatial frequencies the image is almost fully obscured
Describe Optical system (SMTF=Image quality)
Simple lenses or complex lens systems (telescopes and cameras), the MTF gives the modulation transfer for all possible spatial frequencies
Describe the human visual system
CSF is the MTF of the visual system
Neural and cortical processing and the optics of the eye contribute to the final outcome of the CSF
How can we quantify the precision with which an optical lens (system) transfers information?
grating of specfic spatial frequency and contrast
image contrast is measures
the ratio=image quality (MTF)
repeat procedure ranging from low to high to get SMTF
MTF=0 to 1 (1 is the best image quality!!!!)
How does SMTTF change with Lens in focus?
low and moderate frequencies are unaffected, the image is transferred with good fidelity as aberrations (in the optical system) have very little or no effect in lower spatial frequencies and typically affect higher spatial frequencies
How does SMTTF change with Lens in defocus?
reduction in image quality in higher spatial frequencies
How does SMTTF change with translucent lens?
Equal degradation at all spatial frequencies
What is CSF?
Contrast sensitivity function
an observers sensitivity to gratings of widely varied spatial frequency
What is the range and peak of adult CSF?
2-10cpd
peak at 4cpd
In the CSF curve what's on the x-axis and what's on the y-axis?
x-axis: spatial frequency
y-axis: contrast sensitivity
How does the CSF curve for photopic conditions?
largest curve, high frequency cut off 100 cpd
How does the CSF curve change for Mesotopic conditions?
middle curve, high frequency cutoff at 60cpd
How does the CSF curve change for scotopic conditions?
lowest curve, high frequency cutoff 15cpd
Name the two types of CSF?
spatial contrast sensitivity function: sCSF (across space)
Temporal contrast sensitivity function: tCSF (across time)
Name the landmarks of CSF curve and their limitations?
Provides an evaluation of real-world vision
Everything under the CSF is visible
everything above the CSF is invisible
it's a window of visibility
What does the high spatial frequency cut off correspond to?
best VA
What does the peak CS 4cpd correspond to
average receptive field size of retinal ganglion cells
What is the low SF cut off due to?
lateral inhibition throughout the visual system
The lower and higher spatial frequencies require more or less contrast to be detected?
More contrast
highest spatial frequency can be resolved only at a...
very high contrast and this corresponds to the acuity level
What does the shape of CSF reflect?
underlying spatial frequency channels
What is the CSF high frequency cutoff?
60 cpd
visual systems limited ability to resolve detail when the contrast is 100% (normal VA)
What is the relationship between VA and the CSF?
high spatial frequency cutoff is VA
bottom row (100% contrast) represents VA
*Vertically contrast diminish
Low contrast VA not measured routinely in clinic
Why does the visual system show reduction in sensitivity for high spatial frequencies?
optical limitations-due to aberrations
packing density of photoreceptors
The ______ of the CSF is the same for many species but the ______ occurs at different spatial frequencies
Same shape, different peaks
The CSF peak for Falcons is shifted where?
Toward the higher spatial frequencies
What is important about the Macaque monkey spatial CSF curve?
its nearly identical to that of humans
What happens to the high frequency cut-off if the eye is out of focus, such as uncorrected refractive errors (myopia)?
reduction in high spatial frequency cut off
What factors influence CS?
1. optical defocus
2. retinal illuminance
3. Retinal eccentricity
The spatial CSF changes in what 3 ways as mean retinal luminance of the grating is reduced?
1. Peak contrast sensitivity is decreased and shifts toward lower spatial frequencies
2.High-frequency cutoff spatial frequency (acuity) decreases and shifts toward the lower spatial frequency
3. low spatial frequency rolloff becomes less prominent
How does retinal eccentricity affect CSF?
increasing retinal eccentricity causes the CSF to shift towards lower spatial frequency
What are the reasons for decreases in CSF with retinal eccentricity?
1. size of receptive field depends on the number of photoreceptors that converge on a bipolar cell and the number of bipolar cells that converge on a ganglion cell
2. the cortical area devoted to representing the retinal periphery (cortical magnification) which tend to decrease with eccentricity
How does the CS change with aging?
at birth, improves steadily with age
steady in young adults
declines with age
What is the high frequency cut off shift from 8 to 2 cpd due to when illuminance levels are decreased?
transition from photopic, to cone-driven (small) receptive fields to scotopic, rod driven (large) receptive fields
How does CS develop in infants?
sensitivity to higher spatial frequency gratings is very poor at birth, improves steadily with age
Postnatal acuity= infants age in months is cpds
ex: 12months old=12 cpd
How is the contrast sensitivity function of infants different than that of adults?
peak is lower
function is shifted to the left
shape is "low pass" rather than a "band pass" function
When does the overall CS reach adult levels?
7-9 yrs
How can you determine CSF in the clinic?
Charts designed to measure spatial contrast sensitivity functions clinically are based on what's important for recognizing objects
Provide examples of the charts used in the clinic?
Fixed Size, vary contrast
-Pelli-Robinson
-MARS CS (near)
-Rabin
Fixed contrast (low), vary size
-EDTRS
Fixed contrast (high), Vary size
-EDTRS
-Snellen
Variable contrast, vary size
-FACT
VCTS/VISTECH charts
Describe the Pelli Robson Chart
Fixed size, variable contrast
all of the letters in the chart are the same size
consists of 3-letter sets, each triplet has the same contrast
each triplet is 0.15
stop when pt gets 2 or more in a triplet incorrect
What are the normal values for adults and above 60yrs in pelli robson?
Log CS 1.84 (20-39yrs)
Log CS 1.68 (60yrs and up)
the smaller the CS value, the poorer the pts CS
Which chart has grating displayed on a printed chart?
VISTECH
What is a FACT chart? what is the target?
Functional Acuity Contrast Test
Target: Sine wave gratings
Describe MARS CS chart
letter contrast sensitivity test
stop when 2 consecutive mistakes occur
48 different contrast levels, decline gradually 0.04 log unit steps
rapid testing
(the smaller the log CS value=poorer CS)
Why measure CS?
sensitive measure to smaller changes in the visual system
complaints of reduced vision not proportionate to the reduction in high contrast acuity
optical factors
drug usage
monitor disease
What are the factors affecting CS?
refractive error, age, cataract, refractive surgeries, CL induced corneal edema, glaucoma, optic neuropathies, diabetic retinopathy, ARMD, Pituitary Adenoma, Drugs, Toxic chemicals
describe optical corrections of refractive errors?
improves only a limited aspect of a patients VA (no effect on low frequencies)
high spatial frequency resolution is critical (road signs, computers screen, books)
What is the importance of low and middle spatial frequencies for seeing?
Pts with central vision loss whose high frequency spatial resolution is impaired may still be able to perform certain visual task due to retention of low frequencies
(trouble reading but can still walk around)
pts who has deficits at low and moderate spatial frequencies with only minimal reduction at high spatial frequencies may present with 'Complaints' of significant visual impairment
Name a few clinical ocular conditions where CS is affected?
High optical defocus (myopia) -reduces contrast sensitivity primarily at high spatial frequencies
Cataracts- cause reduction is low, moderate and high spatial frequencies
CL induced corneal edema- causes reduced contrast sensitivities across low, moderate and high frequencies
Scarring of the stromal layers-due to trauma or refractive surgery reduces CS at low and moderate levels
Swelling of stroma(Fuchs endothelial dystrophies)-reduces low and moderate frequencies
Corneal epithelial disruptions- low and moderate
Why has the spatial CSF not become a useful diagnostic test for ocular pathology?
the sCSF is sensitive to man ocular disorders but does not have high specificity for an any particular disorder
No unique patterns of spatial CSF loss have emerged that are useful in differential diagnosis of particular condition
Most of these conditions depress the contrast sensitivity at high spatial frequencies so that these conditions are also detected by simple measures of MAR
CS has been no more useful than MAR is detecting ocular disease
When can a dissociation occur between MAR and the spatial CSF?
in conditions that affect the central visual pathway
MS-loss of contrast at low frequencies but remains in high, so MAR is unaffected
Strabismic Amblyopia-loss a middle to high resulting in a reduction in high spatial frequency cut off that is routinely detected in acuity measure
Spatial CSF are more useful in what compared to what?
more useful in assessing the effects of vision problems on the quality of life than used as a first-line diagnostic tool