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Desirable Properties of LA
Non-irritating, Reversible, Low systemic toxicity, Effective as injectable or topical, Short onset time, Adequate duration of action, Does Not produce allergic response, Stable in solution, Sterile.
Sensory neuron
Afferent, carries information from the periphery to the brain, cell body not involved in the process of impulse transmission.
Motor neuron
Carries information from brain to periphery, Cell body involved in impulse transmission and provides metabolic support for the cell.
Myelinating Schwann Cells
Wrap around axons of motor and sensory neurons to form the myelin sheath, faster conduction.
Unmyelinated nerves
Impulse travels slowly.
Nodes of Ranvier
Form gap between two adjoining Schwann cells and their myelin spirals.
Resting state
Impermeable to sodium which prevents massive influx of the ion.
Depolarization
Stimulus excites the nerve, Na+ moves into cell, rapid increase of Na+ moving in.
Repolarization
Electrical potential gradually becomes more negative.
Absolute refractory period
Immediately after the stimulus has initiated an action potential, a nerve is unable for a time to respond to another stimulus.
Relative refractory period
New impulse can be generated but only a stronger than normal stimulus.
Esters
Hydrolyzed in the plasma.
Prilocaine and articaine
With anemic patients can cause methemoglobinemia.
LA BBB
Local anesthetics cross the blood brain barrier.
Cardiac dose
2 cartridges, 0.04 per appointment.
Short duration
30 minutes, does not have vasoconstrictor.
Jet injector
Needleless injection using high pressure liquid that is forced through mucous membranes, not replacement for traditional block anesthesia.
Bevel
Point or tip of the needle.
Short needle
20-25mm.
Long needle
30-35mm.
Gauge
Diameter of the lumen of the needle, smaller the number the greater the diameter of lumen.
Change needle
After 3-4 tissue penetrations.
Cartridge
1.8 mL.
Stopper
Receives the harpoon of aspirating syringe.
Cartridge care and handling
No need to warm the cartridge.
Burning on injection
Normal response to pH of drug.
Overheating the cartridge
Vasoconstrictors.
Topical antiseptic
Prepare the tissues at the injection site before the needle penetration to decrease transient bacteria.
Topical anesthetic
20% benzocaine, Preferably 2 minutes.
Aspirating
Negative pressure.
Injecting
Positive pressure.
ASA III
Severe systemic disease not incapacitating.
Heart Attack
No treatment for 6 months.
Sulfite allergy
Avoid use of vasoconstrictors.
Sulfonamides
Do not administer esters to these patients.
Malignant hyperthermia
Severe reaction to prilocaine and articaine.
Field block
Near larger terminal branches (supraperiosteal or infiltration).
Supraperiosteal injection
Single tooth injection.
PSA positive aspiration
31%.
Palatal anesthesia
Topical anesthesia should be in contact for 2 minutes with pressure anesthesia during the injection.
IA Failing
Even without any operator error, due to the thickness of the mandible.
IA positive aspiration rate
10-15%, highest positive aspiration rate.
Success rate of gow gates block
95% with experience.
Positive aspiration of gow gates
2%.
Injection site for IA
Center of pterygomandibular triangle, bisect thumb ¾ ant/post distance from coronoid notch back to pterygomandibular raphe.
IA bone contacted too soon
Bring syringe more closely superior to mandibular anterior teeth.
IA bone not contacted
Bring syringe more posterior to mandibular molars.
Mental block
Recommended for anesthesia of the facial gingival tissue, anteriors and premolars.
Incisive block
Recommended for anesthesia of the teeth and periodontium and facial soft tissue anterior to mental foramen, anesthetizes teeth, soothing massage for 2 minutes.
Intraosseous anesthesia
Deposition of anesthetic solution into the cancellous bone that supports the teeth.
Intraseptal Injection
Anesthesizes Bone, soft tissue, and root structure in the area of injection.
Uses 27 gauge short needle
Pressure push needle 1-2mm into septum.
Long duration LA
Uses Bupivicaine, oral surgery, prosthodontics, and periodontics.
Bupivicaine
A local anesthetic used in dental procedures.
Needle Breakage
Sudden, unexpected movement of pt or needle, smaller needles, bending needles, poor technique, defective needles.
Management of Needle Breakage
Tell pt to not move and keep mouth open keeping hands in their mouth.
Pain on Injection Prevention
Adhere and review proper injection technique, sharp needles, topical anesthetic, sterile local anesthetic solutions, inject slowly, room temp solution.
Paresthesia Causes
Contaminated solution, trauma around nerve.
Paresthesia Problem
Self inflicted soft tissue injury, loss of taste, painful sensation.
Trismus
Trauma during injection to muscle or blood vessels, not always preventable.
Trismus Management
Heat therapy every 20 minutes.
Hematoma
Not always preventable, no heat.
Infection Causes
Contaminated needle, improper tissue preparation, injecting into infected area.
Infection Prevention
Sterile needles, carefully cap needle, properly care for dental cartridges.
Soft Tissue Injuries
Most frequently occurs in children and disabled adults.
Facial Nerve Paralysis
Unilateral paralysis immediately.
Principles of Any Drug
No drug ever exerts a single action, no clinically useful drug is entirely devoid of toxicity.
Overdose
Absolute or relative over administration, high blood level of drug.
Allergy
Not dose related.
Patient Factors of Overdose
Age, weight, genetics, mental attitude and environment.
Aspirate
Prevent intravascular injection.
Basic Emergency Management
Position, circulation, airway, breathing, definitive care.
Severe Reaction
Rapid onset, 1 minute.
Epinephrine Overdose
Fear, tenseness, restlessness, tremor, perspiration, weakness, dizziness, pallor, respiratory difficulty, palpitations, and throbbing headache.
Allergy Management
Assume true allergy.
Dermatological Allergic Reactions
Uticaria and angioedema.
Respiratory Allergic Reactions
Bronchospasm, dyspnea, cyanosis, wheezing, respiratory distress, flushing, perspiration, tachycardia, increased anxiety, laryngeal edema.
Generalized Anaphylaxis
Unlikely with local anesthesia, clinical death in few minutes.
Oraverse
Reverse anesthesia following injections.
Buffering
Makes injection more reliable and predictable analgesia.
Oraqix
Needle free, 30 second onset, lasts approx 20 minutes, mixture of lidocaine and prilocaine, 5 cartridges max, metabolized in liver.
Titration
Process of administering drug incrementally to specific level or endpoint of sedation.
Elimination and Recovery N2O
Not metabolized in the liver, allows for complete recovery with 100% pure oxygen for a minimum of 5 minutes after termination of the drug, 99% eliminated through lungs.
N2O State
Liquid when compressed into the cylinder.
O2 State
Gas, odorless, colorless, and tasteless.
N2O Cylinder
Full cylinder will have pressure of 750 PSI at 70 degrees, 95% liquid and 5% vapor.
O2 Cylinder
Pressure of 2000 PSI.
Reservoir Bag
Provide source of additional gas, provide mechanism for monitoring the patients respiration, emergency method of positive O2 pressure to pt.
Conduction Tubing
Care should be taken to prevent kinking.
O2 Safe Fail
Minimum of 30% O2 at all times.
Porter Automatic Vacuum Switch
Prevents nitrous oxide from being administered without scavenging.
Appropriate Sedation
Relaxed and comfortable, tingling sensation, feeling warm.
Oversedation
Detachment from environment, dreaming, floating, inability to move, keep mouth open.
Fasting
Before moderate sedation you must do this.