Part 3: RNA dependent synth of DNA/RNA

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8 Terms

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Coronavirus

replication requires an RNA dependent RNA polymerase (this isn’t unique to it just the virus we talked about in class and this applies to all negative strand ssRNA viruses)

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RNA tumor viruses

reverse transcriptase was discovered through work on _

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Reverse transcriptase

functions include rna dependent DNA synthesis (initated by host tRNA), degradation of RNA template and DNA dependent DNA synthesis

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Retroviruses

integrate into host genome

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Long terminal repeat

the ends of retroviruses include

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Packing signal

next to the 3’ LTR what is in a retrovirus genome

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Telomerase

specialized reverse transcriptase (replicates telomerases), maintains the end of the chromosomes

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T loop

extreme single stranded 3’ end loops arounds and base pairs with its complement in the double stranded portion of the telomere.