Acid-Base Concepts & Compensation
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7 Terms
What is acidosis?
Acidosis occurs when pH < 7.35, leading to CNS depression, coma, heart failure, and death.
What are the effects of acidosis on proteins?
Acidosis causes conformational changes in proteins, which alters enzyme activity.
What is alkalosis?
Alkalosis occurs when pH > 7.45, leading to muscle spasms, convulsions, and death.
What are the effects of alkalosis on proteins?
Alkalosis causes conformational changes in proteins, which alters enzyme activity.
What is compensation in acid-base imbalances?
Compensation is the physiological response to normalize pH, either partial or complete.
How fast does respiratory compensation work?
Respiratory compensation can start in minutes and max out in hours.
How fast does renal compensation work?
Renal compensation starts in minutes but can take days to reach full compensation.