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Francesco Redi
first to refute the idea of spontaneous generation
hypothesized that flies must have direct contact with meat for maggots to appear
Heedham
for spontaneous generation
boiled broth with animal and plant matter, sealed, and observed growth
Spallanzani
found heated but sealed broth remained clear unless the flaks were opened and something from the air was causing growth
against spontaneous generation
Pasteur
considered the one to refute spontaneous generation
swan-necked flask experiment
founding father of microbiology
1st observe L and D isomers of Aspergillus
found that fermentation is a biological process
Koch
developed solid media for obtaining pure cultures
1st to use agar to grow bacteria on plates
noted colony morphology
4 postulates helped identify the causative agents of anthrax, tuberculosis, and cholera
Wingogradsky
discovery of microbial diversity
demonstrated that specific bacteria are linked to specific biogeochemical transformations such as nitrogen fixation
Beijernick
developed enrichment culture technique that selectively encouraged growth of specific organisms such as isolating the first aerobic nitrogen fixing bacterium (Azotobacter)
found that bacteria lived in the roots of plants and promote growth
Griffith and Avert Macleod McCarty
streptococcus pneumonia and transformation
evidence that DNA is the molecular basis of heredity that would modify the postulates
DNA could be used ti determine the present of a pathogen
horizontal gene transfer
DNA was transforming strains into pathogenic
Whitaker
5 domain classification of life
Woese
rRNA present in all cells made it it possible to build the first tree of life (used rRNA sequence)