Regulatory proteins tropomyosin and troponin block myosin bonding sites on actin. When a neuron stimulates a muscle, the release of calcium is triggered and calcium ions bind with troponin which changes the shape of tropomyosin, causing it to move off of myosin binding sites. This provides myosin with access to actin. An ATP molecule binds to a myosin head, where it is hydrolyzed into ADP and a phosphate. The myosin head performs a power stroke in which it moves towards the center of the sarcomere, releasing the ADP and phosphate. The binding of another ATP to the myosin head allows it to detach from the actin filament to restart the cycle