Hematology Solo 3 Kahoot and Study Questions

Which of these is the terms that describes a macrophage surrounded by maturing erythroblasts

Erythropoietic islands

Which of the following changes does NOT occur as RBCs mature?

The cell volume increases

What is the least mature form of a red blood cell

Rubriblast

What is the correct maturation order of RBCs?

Rubriblast, Prorubricyte, Rubricyte, Metarubricyte, Reticulocyte, RBC

Name this cell

Metarubricyte

Pluripotent stem cells expressing only CD34 antigens are capable of producing?

Lymphoid and myeloid stem cells

I remember how to calculate a corrected WBC count, given an nRBC and uncorrected WBC count

True

What are Howell-Jolly bodies associated with?

Splenectomy

What are pappenheimer bodies composed of?

Iron deposits

Which of these is the Greek term for target cells?

Codocyte

What are stomatocytes associated with?

Rh Null phenotype

What is basophilic stippling associated with?

Lead poisoning

Spherocytes have a ______ osmotic fragility

Increased

Lowered pH results in _________ on the hemoglobin oxygen dissociation curve

A shift to the right

Increased 2,3-DPG results in __________ on the hemoglobin oxygen dissociation curve

A shift to the right

Presence of hemoglobin F results in _________ on a hemoglobin oxygen dissociation curve

A shift to the left

Hemoglobin A consists of

Two alpha and two beta chains

Which of these lines represents beta polypeptide chains of hemoglobin

2

Which of these is the first step of heme synthesis

Delta aminolevulinic acid

What is the next to last step in heme synthesis

Protoporphyrin IX

“Couples oxidative catabolism of glucose with NADP reduction, which is required for a glutathione reduction” describes:

Hexose monophosphate shunt

If a patient has an increased level of red blood cells and erythropoietin, a possible disorder would be

Secondary polycythemia

The progression of erythropoiesis from prenatal life to adulthood is

yolk sac, liver and spleen, and red bone marrow

Stimulation of erythropoietin is caused by

Tissue hypoxia

Increased erythropoietin production in secondary polycythemia can be caused by

All of the above (chronic lung disease, smoking, renal neoplasms)

Relative polycythemia exists when

The plasma volume is decreased

Increased amounts of 2,3-DPG ___________ the oxygen affinity of the hemoglobin molecules

Decreases

The limited metabolic ability of erythrocytes is owing to

No mitochondria for oxidative metabolism

The net gain of ATPs in the Embden-Meyerhof glycolytic pathway is

2

The most common erythrocytic enzyme deficiency involving the Embden-Meyerhof glycolytic pathway is a deficiency of

Pyruvate kinase

To maintain reduced levels of methemoglobin in the red blood cell, what chemical is necessary to maintain heme iron in a functional (2+) state

DecNADH

Why would a patient have Heinz bodies in red blood cells?

Decreased amounts of reduced Glutathione

The number of heme groups in a hemoglobin molecule is

4