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Anatomy of the Arm
The structure including humerus, radius, ulna, deltoid, scapula, clavicle; basis of biomechanical modeling.
Muscle
A bundle of muscle fibers containing actin and myosin; generates force by contraction.
Muscle Fiber
Individual cells in a muscle that contract using actin-myosin interactions.
Actin
Thin contractile protein that slides past myosin during muscle contraction.
Myosin
Thick contractile protein generating force when interacting with actin.
Tendon
Fibrous tissue attaching muscle to bone; transmits muscle force.
Parallel Fibers
Muscle fibers arranged side by side; more parallel fibers = greater force.
Force Development
Generation of tension in muscle; results from contraction pulling bones.
Free Body Diagram
A simplified drawing showing all forces acting on the arm system.
Static System
A system where sum of forces and torques = 0; no acceleration occurs.
Newton's First Law
ΣF = 0 and Στ = 0 for static equilibrium.
ΣFx = 0
Sum of horizontal forces must equal zero in static equilibrium.
ΣFy = 0
Sum of vertical forces must equal zero in static equilibrium.
Στ = 0
Sum of torques about a pivot must equal zero.
Torque (τ)
Rotational equivalent of force; τ = r × F; increases with distance from pivot.
Moment Arm
Perpendicular distance from pivot to line of action of the force.
Shoulder Joint
Fulcrum/pivot point for static arm model torque calculations.
Fload
Weight held in the hand; produces a downward torque.
Farm
Weight of the arm; acts at its center of gravity (L/2).
Fdelt
Force generated by the deltoid muscle to hold/raise the arm.
Fshoulder
Net reaction forces of the shoulder muscles/joint.
Deltoid Muscle
Shoulder muscle responsible for lifting the arm; small insertion angle increases required force.
Angle of Insertion (θ)
Angle between deltoid force direction and humerus; determines effective torque.
Insertion Point
Location where deltoid attaches; assumed L/4 from shoulder.
Arm Length (L)
Distance from shoulder to hand; affects torque created by loads.
Arm Diameter (2r)
Used to approximate the volume and weight of the arm.
Arm Shape Assumption
Typically simplified to a cylinder for mass estimation.
ρ (rho)
Density of tissue; used to estimate total arm mass: ρ × Volume.
Volume (arm)
πr²L for cylindrical approximation used in Farm calculations.
Center of Gravity
Point where arm weight acts; typically at L/2.
Torque Equation
τ = rF sin θ; used for deltoid torque and external load torque.
Deltoid Torque Eq.
τdelt = Fdelt × (L/4) × sin θ.
Load Torque
τload = Fload × L.
Arm Torque
τarm = Farm × (L/2).
Equilibrium Equation
Fdelt = (2Farm + 4Fload) / sin θ.
Cross-Sectional Area
Determines muscle's maximum force capacity.
Force per Unit Area
Deltoid muscle produces ~30-40 N/cm² (50 lb/in²).
Simulation
Graphing Fdelt vs. Fload to test model sensitivity.
Model Assumptions
Arm geometry, muscle angle, insertion point, uniform density, etc.
Validation
Comparing computed Fdelt to physiological capacity.
Achilles Tendon Model
Another static torque example using foot geometry.
Achilles Tension (T)
Force needed in tendon to counteract foot load and produce torque.
Vector Forces
Forces include magnitude + direction; represented with arrows.
Static Stance
Assumption for Achilles model: body is not accelerating.
Neuron
Basic signaling cell of the nervous system; sends information in one direction.
Dendrites
Branch-like structures receiving signals from other neurons.
Cell Body (Soma)
Contains nucleus; integrates incoming signals.
Axon Hillock
Trigger zone for action potentials; site of summation.
Axon
Long process transmitting electrical impulses away from soma.
Synapse
Junction where axon terminal communicates with another neuron.
Myelin
Insulating sheath increasing conduction speed.
Nodes of Ranvier
Gaps in myelin enabling saltatory conduction.
One-way Flow
Information travels dendrite → soma → axon hillock → axon → synapse.
Convergence
Many neurons synapse onto one neuron.
Divergence
One neuron synapses onto many neurons.
CNS
Central Nervous System; brain and spinal cord.
PNS
Peripheral Nervous System; afferent + efferent neurons.
Afferent Neurons
Carry sensory information to CNS.
Efferent Neurons
Carry motor commands from CNS.
Somatic NS
Controls voluntary skeletal muscle movements.
Autonomic NS
Controls involuntary functions (heart, vessels, glands).
Gray Matter
Neuron cell bodies; outer brain layer, inner spinal cord.
White Matter
Myelinated axons; inner brain, outer spinal cord.
Brodmann Areas
52 cortical regions defined by cellular structure.
Primary Motor Cortex
Region controlling voluntary movement.
Primary Somatosensory
Region receiving touch, pressure, and stretch info.
Visual Cortex
Region in occipital lobe responsible for vision.
Auditory Cortex
Temporal lobe region for sound processing.
Wernicke's Area
Language comprehension center.
Broca's Area
Speech production center.
Reflex Arc
Rapid, involuntary response requiring afferent + efferent neurons.
Interneuron
Modulates reflex by inhibiting or exciting motor neurons.
Knee Jerk Reflex
Stretch muscle → ↑ afferent firing → extensor contracts; flexor inhibited.
Muscle Spindle
Stretch receptor monitoring muscle length.
Alpha Motor Neuron
Efferent neuron causing muscle contraction.
Inhibitory Interneuron Reduces firing of opposing muscle groups.
Stretch Reflex
Negative feedback loop maintaining constant muscle length.
Negative Feedback
Output reduces original stimulus; stabilizes system.
Firing Rate
Frequency of action potentials; encodes stimulus intensity.
Resting Membrane Pot. Baseline neuron voltage (~ -70 mV) determined by ion gradients.
Chemical Gradient
Difference in ion concentration across membrane.
Electrical Gradient
Charge difference across membrane.
Electrochemical Grad. Combined chemical + electrical force driving ion movement.
Nernst Potential
Voltage where net ionic movement = 0 for a specific ion.
Nernst Equation
Ex = -61/z * log([Xi]/[Xo]); determines equilibrium potential.
ENa
Sodium Nernst potential ≈ +60 mV.
EK
Potassium Nernst potential ≈ -90 mV.
Conductance (g)
Permeability to an ion; inverse of resistance.
Chord Conductance Eq. Vm = (gK/gT)EK + (gNa/gT)ENa + ... ; weighted average of ion potentials.
Dominant Ion
Ion with highest conductance determines resting Vm (usually K+).
Graded Potential
Small voltage changes; diminish over distance; input signals.
EPSP
Excitatory postsynaptic potential; depolarizes cell.
IPSP
Inhibitory postsynaptic potential; hyperpolarizes cell.
Temporal Summation
Input signals occurring closely in time add together.
Spatial Summation
Inputs from multiple synapses add together.
Threshold
Voltage required to trigger an action potential.
Neurotransmitter Bind Opens ion channels causing EPSP or IPSP.
Receptor Type Effect
Same neurotransmitter can cause EPSP or IPSP depending on receptor.
Action Potential
Rapid, all-or-none reversal of membrane potential.
Depolarization
Vm becomes more positive due to Na+ influx.