Pre-EMS Call Medication Check
Ensure all equipment on the ambulance is fully functional, verify medications are not expired or damaged, and ensure medications are readily available in the correct quantity.
Familiarity with Drug System
Be thoroughly familiar with the system used for exchanging and replacing outdated or damaged drugs.
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Pre-EMS Call Medication Check
Ensure all equipment on the ambulance is fully functional, verify medications are not expired or damaged, and ensure medications are readily available in the correct quantity.
Familiarity with Drug System
Be thoroughly familiar with the system used for exchanging and replacing outdated or damaged drugs.
Documentation and Security
Be responsible for the documentation and security of all controlled substances carried on the ambulance and account for all controlled substances that were wasted.
Follow Policies and Procedures
Adhere to local policies and procedures for drug distribution, security, and accountability.
Medical Asepsis
Practice of preventing contamination of the patient using aseptic technique, aimed at preventing contamination when performing invasive procedures.
Clean Technique vs. Sterile Technique
Some equipment in the prehospital environment is sterilized for patient safety; sterile technique is the destruction of all living organisms using heat, gas, or chemicals.
Examples of Medical Asepsis
Handwashing, wearing gloves, and keeping equipment clean.
Medically Clean
Cleaning the patient site with iodine and alcohol before starting an IV.
Contamination Prevention
If an IV catheter falls or contacts a contaminated surface, discard it and use a new one.
Antiseptics
Used to cleanse areas before invasive procedures and are non-toxic to living tissues.
Common Antiseptics
Isopropyl alcohol (rubbing alcohol) and iodine.
Disinfectants
Toxic to living tissues; should only be used on nonliving objects.
Common Disinfectants
Virex, Cidex, Microcide, and sodium hypochlorite (bleach).
First Rule of Routine Precautions
Treat all body fluids as potentially infectious.
Disposal of Contaminated Equipment
After an IV catheter or needle penetrates a patient's skin, it becomes contaminated.
Sharps
Contaminated items that can cause injury, including IV needles and catheters, broken ampules or vials.
Safety Practices to Minimize Risk of Needlesticks
Follow the agency's exposure control plan.
Total Body Water (TBW)
Comprises 60% of adult body weight (approx. 42 kg in a 70-kg patient).
Intracellular Fluid (ICF)
45% of body weight (about 28 L), inside the cells.
Extracellular Fluid (ECF)
15% of body weight (about 14 L), outside the cells.
Interstitial Fluid
10.5% of body weight (approx. 10 L), bathing the cells.
Intravascular Fluid (Plasma)
4.5% of body weight (approx. 4 L), within blood vessels, transporting cells and nutrients.
Fluid Movement
Continuous movement of fluids and solutes between compartments.
Homeostasis
Maintains consistency in content and composition.
Imbalance
Leads to disease or issues.
Solvent
Fluid that dissolves substances (water in the body).
Solute
Dissolved particles (e.g., electrolytes, nonelectrolytes).
Electrolytes
Charged atoms or molecules that conduct electricity when dissolved in water.
Cations
Positive charge (e.g., sodium, potassium, calcium, magnesium).
Anions
Negative charge (e.g., bicarbonate, chloride, phosphate).
Electrolyte Measurement
Measured in millimoles per liter (mmol/L).
Electrolyte Balance
Regulates essential body functions like water levels, muscle contractions, and cardiac function.
Sodium (Na+)
Main cation in extracellular fluid; regulates water distribution and cellular perfusion.
Potassium (K+)
98% inside cells, principal intracellular cation; regulates neuromuscular function and glucose metabolism.
Hypokalemia
Low potassium causes muscle, GI, and cardiac disturbances.
Hyperkalemia
High potassium causes hyperstimulation of nerve cells, leading to cardiac arrest.
Calcium (Ca+2)
Essential for bone growth, muscle function, heart muscle, nerve function, and blood clotting.
Hypocalcemia
Low calcium causes muscle cramps, spasms, hypotension, and vasoconstriction.
Hypercalcemia
High calcium causes muscle weakness, lethargy, ataxia, vasodilation, and flushed skin.
Magnesium (Mg+2)
Coenzyme in protein and carbohydrate metabolism; controls neuromuscular irritability similar to calcium.
Bicarbonate (HCO3−)
Regulates acidosis and alkalosis; critical in the carbonic acid/bicarbonate buffer system.
Chloride (Cl−)
Regulates extracellular fluid and stomach pH.
Phosphorus (P)
Component of adenosine triphosphate (ATP), the body's energy source.
Nonelectrolytes
Substances without an electrical charge, including glucose and urea.
Glucose
Normal blood concentration is 4 to 8 mmol/L.
Governing Principle
Unequal concentrations of water and electrolytes across a cell membrane will move to balance on both sides of the membrane.
Concentration Gradient
Created when concentrations of charges or compounds are higher on one side of the membrane.
Diffusion
Movement of particles from high to low concentration.
Filtration
Movement of water and dissolved compounds through cell membranes, commonly used by kidneys to clean blood.
Active Transport
Uses energy (ATP) to maintain imbalances of compounds across the membrane.
Osmosis
Movement of water from low solute concentration to high concentration through a selectively permeable membrane.
Homeostasis (Disturbances)
The body's ability to maintain a stable internal environment; illness can disrupt this balance, leading to fluid and electrolyte imbalances.
Normal Fluid Loss
A healthy person loses 2 to 2.5 L of fluid daily through urine, exhalation, and skin.
Dehydration
Inadequate total systemic fluid volume.
Common in Dehydration
Older adults and young children.
Dehydration Process
Fluid shifts from the vascular to interstitial and intracellular compartments, leading to a systemic fluid deficit.
Dehydration Signs and Symptoms
Decreased consciousness, Orthostatic hypotension, Tachypnea, Dry mucous membranes, Tachycardia, Poor skin turgor, Flushed, dry skin.
Causes of Dehydration
Diarrhea, vomiting, gastrointestinal drainage, hemorrhage, insufficient fluid/food intake.
Overhydration
Increased total systemic fluid volume.
Overhydration Process
Fluid fills the vascular compartment, moves into the interstitial compartment, and then into the intracellular compartment.
Risks of Overhydration
Can lead to edema or even death.
Overhydration Signs and Symptoms
Shortness of breath, Puffy eyelids, Edema, Polyuria, Moist crackles (rales), Acute weight gain.
Causes of Overhydration
Unmonitored IV lines, kidney failure, prolonged hypoventilation.
Sterility of IV Fluids
Each IV fluid bag is sterile, with the compounds and ions in the solution being identical to those in the body.
Sodium as Benchmark
Sodium concentration is used to calculate a solution's tonicity.
Sodium Concentration in Body Cells
The concentration of sodium in body cells is approximately 0.9%.
Altering Sodium Concentration
Altering sodium concentration in IV solutions can move water into or out of fluid compartments in the body.
Types of IV Solutions
Three Basic Types: Crystalloids, Colloids, Blood Products.
Crystalloid Classification
Isotonic, Hypotonic, Hypertonic.
Fluid Movement in IV Fluids
IV fluids can affect tonicity of the extracellular fluid (ECF), with potential serious consequences.
Isotonic Solutions Definition
Have almost the same osmolarity as serum and other body fluids.
Isotonic Solutions Effects
Expands the intravascular compartment without noticeable fluid shifts to/from other compartments.
Indications for Isotonic Solutions
Used for hypotensive or hypovolemic patients.
Precautions for Isotonic Solutions
Careful to avoid fluid overload, especially in patients with hypertension or heart failure.
Examples of Isotonic Solutions
Normal Saline (0.9% Sodium Chloride), Lactated Ringer (LR), D5W (5% Dextrose in Water).
Hypotonic Solutions Definition
Osmolarity lower than that of serum.
Hypotonic Solutions Effects
Dilutes serum and causes water to move from the vascular compartment to the interstitial compartment.
Indications for Hypotonic Solutions
Hydrates cells while depleting the vascular compartment.
Risks of Hypotonic Solutions
Sudden fluid shift may cause cardiovascular collapse or increased intracranial pressure (ICP).
Example of Hypotonic Solutions
D5W when used for an extended period.
Hypertonic Solutions Definition
Osmolarity higher than that of serum, meaning they have a higher ionic concentration than serum.
Hypertonic Solutions Effects
Pulls fluid and electrolytes from the intracellular and interstitial compartments into the intravascular compartment.
Indications for Hypertonic Solutions
Stabilizes blood pressure, increases urine output, and reduces edema.
Precautions for Hypertonic Solutions
Careful monitoring is required to prevent fluid overload, especially in patients with heart or kidney issues.
Crystalloid Solutions
Contain dissolved crystals (salts or sugars) in water.
Effectiveness of Crystalloid Solutions
Cross membranes and alter fluid levels, making them suitable for prehospital care of injured patients needing fluid replacement.
Replacement Rule
3-to-1 Replacement Rule: For every 1 mL of blood lost, 3 mL of isotonic crystalloid solution is required.
Fluid Loss from Crystalloid Solutions
Two-thirds of infused crystalloid solution will leave the vascular spaces in about 1 hour.
Caution for Crystalloid Solutions
Crystalloid solutions cannot carry oxygen.
Large Fluid Boluses
Large fluid boluses (10-20 mL/kg) should maintain perfusion, not raise blood pressure to normal levels, to avoid diluting remaining blood volume and interfering with hemostasis.
Colloid Solutions
Contain large molecules (typically proteins) that cannot pass through capillary membranes and stay in the vascular compartment.
Effects of Colloid Solutions
High osmolarity draws fluid from the interstitial and intracellular compartments into the vascular compartment.
Colloid Solutions Effectiveness
Effective in reducing edema and expanding the vascular compartment.
Risks of Colloid Solutions
Can cause dramatic fluid shifts, placing the patient in danger if not controlled.
Colloid Solutions Usage
Rarely used in prehospital settings.
Examples of Colloid Solutions
Albumin, dextran, pentaspan.
Oxygen-Carrying Solutions Best Option
Whole blood is the best fluid to replace lost blood, as it contains hemoglobin, which carries oxygen to cells.
Use of O-negative Blood
O-negative blood (universally compatible) may be used in some prehospital settings (e.g., aeromedical or mass-casualty situations).
Synthetic Blood Substitutes
Research and trials are ongoing with synthetic blood substitutes that can carry oxygen and expand circulating volume.
IV Therapy Definition
Involves cannulation of a vein with a catheter to access the vascular system.