CD4+ T Helper Cell Subsets

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1
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What pathogens do TH1 cells target?

Intracellular pathogens

2
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What are the main functions of TH1 cells?

Activate macrophages and stimulate CD8+ cells

3
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What pathogens do TH2 cells target?

Extracellular pathogens

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What antibody cell is associated with TH2 responses?

IgE

5
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Which cells are activated by TH2 cells?

Eosinophils, basophils, mast cells

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What pathogens do TH17 cells target?

Extracellular bacteria and fungi

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What is a key role of TH17 cells?

Recruitment of neutrophils and inflammatory cells

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Which T helper subset is induced in early infection?

TH17

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Which subset promotes cell-mediated immunity?

TH1

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Which subset supports antibody class switching?

TH2