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Behavior Modification Strategies
-SMART Goals
-Self-monitoring
-Social Networking
-Reduce Triggers
Which is not a behavior modification strategy?
SMART Goals
Constant measuring weight
Social Groups
Journaling
Constant measuring weight
What are the 5 parts of energy expidenture?
-BMR
-RMR
-TEF
-PAEE
-NEAT
BMR
Basic Metabolic Rate
The amount of energy the body needs at rest to maintain basic physiological functions. It accounts for the largest portion of total energy expenditure.
RMR
Resting Metabolic Rate
Similar to BMR but measured under less strict conditions. It represents the energy required to maintain basic bodily functions while at rest but not in a completely fasted or stress-free state.
TEF
Thermic Effect of Food
The energy required to digest, absorb, and metabolize food. It typically accounts for about 5-10% of total daily energy expenditure.
PAEE
Physical Activity Energy Expidenture
The energy expended through all forms of movement.
NEAT
Non-Exercise Activity Thermogenesis
The energy expended through non-exercise movements, such as fidgeting, posture maintenance, and spontaneous physical activities.
Bioelectrical impedance analysis (BIA)
Based on the assumption that adipose tissue has a greater electrical resistance than tissue. Varying hydration levels can affect results.
Waist circumference standards
Women: > 35 puts at higher risk
Men: > 40 puts at higher risk
Waist to height ratio for women is
<0.85
Lower body fat distribution is associated with
menopause
Upper body fat distribution is associated with
distributes fat directly to liver and puts person at higher risk of CVDs
Transcription is
goes first, takes lagging strand/RNA(the part that was just copied) and gets separated into mRNA
Translation is
the mRNA gets translated into codons from the tRNA then get attached to other amino acid and then becomes new protein
The nine essential amino acids are
Tryptophan
Phenylalanine
Methionine
Histidine
Isoleucine
Valine
Lysine
Threonine
Leucine
What defines an essential amino acid?
An essential amino acid is one that cannot be synthesized by the body and must be obtained through diet. These amino acids are crucial for various physiological functions.
Pancreatic Enzymes (small intestine)
Trypsin
Chymotrypsin
Proelastase
Procarboxypeptidase
Major Classes of Proteases (breaks down protein)
-Endopeptidase
-Exopeptidase
-Enteropeptidase
-Pepsin
Endopeptidase
break peptide bonds within the protein chain
Exopeptidase
Remove amino acids from the ends of the protein chain
Enteropeptidase
Converts chyme to trypsin, precursor to protease
Pepsin
Secreted in the stomach
Complete Protein
contain all nine amino acids
Incomplete Protein
Lack one or more essential amino acids
Complementary Protein
foods that together make up all nine essential amino acids
Formula for protein requirement given weight
Lbs / 2.2kg = X
Xkg x 0.8 = protein recommendation
Calculate protein requirement for someone who weights 200 lbs
160 g
140g
110g
180g
160 g
Non-modifiable risk factors for CVD
Age
Sex
Hereditary problems
Modifiable risk factors for CVD
Smoking
High BP
inactivity
excess body fat
Cholesterol levels
Diabetes
Pick the non modifiable risk factor for CVD
Diabetes
High BP
Age
Smoking
Age
VLDL
Very Low Density Lipoprotein
which is a type of lipoprotein that carries triglycerides (a type of fat) in the blood. VLDL is considered a "bad" cholesterol because high levels can lead to plaque buildup in the arteries, increasing the risk of heart disease and stroke.
IDL
Intermediate Lipoprotein
transitional lipoprotein between Very Low-Density Lipoprotein (VLDL) and Low-Density Lipoprotein (LDL)
LDL
Low Density Lipoprotein
Transports cholesterol/lipids from the liver to body cells
HDL
High Density Lipoprotein
Good cholesterol, helps maintain cholesterol levels reducing associated chronic diseases
How are different lipoproteins transported in the blood in a fasted state?
During fasting, stored triglycerides in adipose tissue are broken down into free fatty acids and glycerol through lipolysis. The carrier albumin. The liver packages fatty acids into VLDL, which then circulates and delivers triglycerides to tissues. As VLDL loses triglycerides, it converts into intermediate-density lipoprotein (IDL) and then LDL.
How are different lipoproteins transported in a fed state?
fed state, the major lipoprotein responsible for fatty acid transport in the blood is chylomicrons. These are absorbed by intestinal cells and reassembled into triglycerides, which are then packaged into chylomicrons. Chylomicrons enter the lymphatic system and then the bloodstream. They deliver fatty acids to high energy organs.
The digestive enzymes for lipids
lingual lipase
gastric lipase
pancreatic lipase
What is not a digestive enzyme for lipids
lingual lipase
esophageal lipase
pancreatic lipase
gastric lipase
esophageal lipase
What is a glycerolipid?
-it has a glycerol backbone and a one tail or more.
-Glycerolipids are essential for cell membranes, energy storage, and signaling
What is a phospholipid?
-glycerol backbone, 1+ fatty acid tail, and a phosphate group
-make up cell membranes
What is a cholesterol?
-has multiple rings
-It is an essential component of cell membranes and is also a precursor hormones and vitamin D.
What is a fatty acid?
In its simplest from: acid and methyl group
What is saturated fat?
linear and no double bond
What is an unsaturated fat?
-liquid at room temp
-Cis and trans forms
-Typically plant derived
-Trans form is linear
Linoleic acid
Omega-6
MUFA
-Monosaturated fatty acid
-linoleic acid
PUFA
-Polysaturated fatty acid
-alpha-linoleic acid
What is the Calorie lipid recommendation?
20-35% of kCal diet
Glycemic Index
ratio of blood glucose response to a food, high GI then more glucose is made
Glycemic Load
It takes into account both the glycemic index (GI) of the food and the amount of carbohydrates it contains.
Criteria for diabetes diagnosis
-HypOglycemia: low-blood sugar 70 mg/dL
-HypERglycemia: 125 mg/dL
-Fasting blood glucose is 100 to 125 mm per deciliter, or HbA1c is 5.7% to 6.4%
Hypoglycemia
70 mg/dL
Hyperglycemia
125 mg/dL
What is the criteria for a diabetes diagnosis using HbA1c?
5.7-6.4%
Function of Insulin?
release insulin to lower blood glucose
Function of glucagon?
Glucose is gone - raise blood glucose, catabolic, breaks down glycogen
Carbohydrate digestion enzymes are
Salivary amylase
Pancreatic a-amylase
Maltase
Isomaltase
Sucrase
Lactase
ID the non-carbohydrate digestion enzyme
Lactase
halotase
salivary amylase
maltase
halotase
Amylose
-Helical structure
-a linear, unbranched polysaccharide made of α-D-glucose units linked by α-1,4 glycosidic bonds
Amylopectin
-River like branching
-a highly branched, water-insoluble polysaccharide and a major component of starch
Glycogen
-Star branching, many branches for more energy
-the stored form of glucose that's made up of many connected glucose molecules
List the three DIsaccharides
Sucrose: glucose + fructose
Lactose: glucose + galactose
Maltose: glucose + glucose
Which one is a DIsaccharide
Sucrose
glucose
galactose
Sucrose
List the three MONOsaccharides
Glucose
Fructose: fruit sugar HFCS
Galactose
Select the MONOsaccharide
Lactose
Galactose
Sucrose
Galactose
List the dietary fiber recommendations
M: 38 g
F: 25 g
OR 45-65% of total calories
Epigenetics
focuses on individual gene modifications, like DNA methylation or histone modifications, that regulate how genes are turned on or off.
Epigenomics
looks at the entire genome’s epigenetic changes, studying patterns across all genes in an organism. Gene expression.
Salivary Amylase
starch-digesting enzyme produced by salivary glands and pancreas; starts digestion of carbohydrates
Lingual Lipase
fat-digesting enzyme produced by salivary glands, stomach, and pancreas
Pepsin
begins digestion of protein
Pancreatic lipase
finishes lipid digestion
Sucrase, maltase, isomaltase and lactase all…
finish carbohydrate digestion
Aminopeptidase, tripeptidase, and dipeptidylpeptidase all…
finish amino acid/protein digestion
Enterpeptidase
cleave trypsinogen to trypsin
Digestive enzymes that originate from the pancreas (4)
Trypsinogen
Chymotrypsinogen
Procarboxypeptidase
Proelastase
Insulin is a…
hormone for digestion
Lowers blood sugar by promoting glucose uptake into cells and storage as glycogen in the liver.
Glucagon is a…
hormone for digestion
Raises blood sugar by stimulating glycogen breakdown in the liver to release glucose.
Ghrelin is a…
Hormone for digestion
Known as the "hunger hormone," it stimulates appetite and food intake.
Leptin is a…
hormone for digestion
The "satiety hormone," it signals the brain to reduce appetite and increase energy expenditure.
Estrogen is a…
hormone for digestion
Affects fat distribution and metabolism, playing a role in appetite regulation.
Testosterone is a…
hormone for digestion
Supports muscle mass and metabolism, influencing energy utilization.
Secretin is a…
hormone for digestion
Regulates digestion by stimulating the pancreas to release bicarbonate, neutralizing stomach acid.
CCK is a…
hormone for digestion
stimulates pancreatic enzyme release & gallbladder contraction
Gastrin is a…
hormone for digestion
promotes gastric motility and secretions from chief/parietal cells
How many organ systems are we required to know?
12
What is not an organ system to know?
Integumentary
Respiratory
Male Reproductive
Circulatory
Circulatory
Integumentary organ system
hair
skin tissue
sweat glands
protects against environment
Skeletal organ system
bones
ligaments
Provides structure
forms blood cells
Muscular organ system
skeletal muscles
tendons
movement so can heat body
Nervous organ system
brain
spinal cord
sense organs
respond to stimuli
coordinates activites
Endocrine
pituitary gland
pancreas
gonads
metabolic activity
controls growth structure
controls functions
Cardiovascular organ system
heart
blood vessels
distributes blood cells and nutrients
assists in body temp
Lymphatic organ system
spleen
thymus
tonsils
defends against infection and disease
absorbs dietary fats
Respiratory organ system
larynx
sinus
trachea
O2 to blood and off of it
communication
Digestive organ system
teeth
liver
intestines
digestion of food
absorb/conserve nutrients
Urinary organ system
kidneys
ureters
urethra
blood waste products
regulations ions and pH
Male Reproductive organ system
testes
epididymis
prostate
produces sperm
sexual intercourse
Female Reproductive organ system
ovaries
uterus
vagina
produces oocytes
support embryo/fetus
milk production
sexual intercourse