Unit 5 Prototypes MOA

Cytarabine and Methotrexate

Antimetabolites: cell cycle specific analogues that work by antagonizing the actions if key cellular metabolites

Cyclophosphamide and Mechlorethamine

Alkylating Drugs: prevent cancer cells from reproducing

Doxorubicin MOA

Blocks DNA synthesis

Cyclosporine

Immunosuppressant: suppress certain T/lymphocyte cell lines

Diptheria, tetnus to toxoids, acellular pertussis, hepatitis b immunoglobulin, influenza, and varicella virus vaccines

Immunizing drugs: they are given intramuscularly to work by stimulating the humoral immune system

Antacids

Neutralizes gastric acidity

Famotidine (Pepcid)

Blocks H2 receptor of acid producing parietal cells

Omeprazole (Prilosec)

Blocks gastric acid secretion

Sucralfate

mucosal protectant

Senna and Lactulose

Reduces serum ammonia levels, promotes bowel movements

Laxative

Diphenoxylate with Atropine and Loperamide

Inhibits GI motility and GI propulsion

Anti-diarrheal/ opioid

Meclizine, Metoclopramide (Reglan), and ondansetron

blocks one of the vomiting passageways

Ascorbic Acid (Vitamin C)

Reversibly oxidized to dehydroascorbic acid and acts in oxidation-reduction reactions

Calcium

Building blocks for body structures

Vitamin k

Effective blood clotting

epoetin alfa

Stimulates red blood cell progenitor cells in the bone marrow

Erythropoiesis stimulating drugs

Ferrous Sulfate

Oxygen carrier in both hemoglobin and myoglobin and is critical for tissue respiration

Folic Acid

Erythropoiesis and synthesis of DNA and RNA

Bacitracin

Inhibits bacterial wall synthesis

Antimicrobials

Benzoyl Peroxide

Continuously liberates active oxygen in the skin

Anti acne

Clotrimazole

Controls fungal infections

Anti fungal

Pilocarpine

Allows for changed of the eye

Cholinergics (miotics)

Timolol

Reduce elevated and normal intraocular pressure

Beta adrenergic blocker

Gentamicin

Destroys the invading organism

Anti microbial

Tetracaine

Stabilize the membranes of nerves, which results in a decrease in the movement of ions into and out of the nerve endings

Topical anesthetic

carbamide peroxide

Softens and lubricates ear wax

Ear wax emulsifiers