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What is Microbiology?
A study of microorganisms, or living things too small to be seen with the naked eye
Why study microbiology?
Microorganisms are an essential part of human life
Why are microorganisms essential to human lives?
Produce 50% of O2, responsible for resources, and hamburgers
Examples of friendly microbes
Lactobacillus, saccharomyces, and propionibacterium sharmanii
What is bioremediation?
Removal of pollutants using living things
Examples of deadliest microbes
Flu Virus, HIV Virus, and Ebola Virus
How did Robert Hooke (1665) contribute to microbiology?
Invented the first simple microscope 30x magnification and observed cells, leading to the Cell Theory
How did Leeuwenhoek (1673) contribute to microbiology?
Invented microscopes with better magnification (275x) and was the first to observes microorganisms
6 types of microorganisms
Bacteria and Archaea, Algae, Protozoans, Fungi, Parasitic worms, and Viruses
What are the 5 kingdoms by Whitaker?
Monera, Protista, Animalia, Fungi, and Plantae
The 3 Domains by Carl Woese?
Eukarya, Bacteria, and Archaea
Difference between eukaryotes and prokaryotes:
Eukaryotes have a membrane-bound nucleus and larger structures, while prokaryotes are smaller single-celled organisms and lack a nucleus
What are the characteristics of Bacteria?
Lacks a nucleus, unicellular, and has a peptidoglycan cell wall
What are the characteristics of Archaea?
Lacks a nucleus, unicellular prokaryote that lives in extreme environments, unusual cell wall with no peptidoglycan
What are the characteristics of Fungi?
Cells walls made of chitin, yeasts are single-celled and oval, molds are multicellular and filamentous, and obtains food by absorption of organic materials
What are the characteristics of protozoa?
Animal-like protists, no cell wall, unicellular, and categorized by movement
What are the characteristics of algae?
Plant-like protists, have a cell wall, photosynthetic, and unicellular or multicellular
What are the characteristics of Helminths?
Parasitic worms, microsopic stage of life cycle, and eukaryotes
What are the characteristics of Viruses?
Non living and dependent on host replication
What is abiogenesis, or spontaneous generation?
Living organisms could arise spontanesously from nonliving matter
What did Francesco Redi discover?
Maggots appear only when flies can lay eggs on meat
How did John Needham contribute to the debate on spontaneous generation?
He heated nutrient broth, sealed with cork, and the broth became cloudy
How did Lazzaro Spalanzani contribute to the debate on spontaneous generation?
He heated nutrient broth for 1 hour, sealed by melting the neck of the bottle, and the broth remained clear
Who disproved spontaneous generation?
Louis Pasteur disproved spontaneous generation using swan-necked flasks, letting air in while trapping microbes and the broth stayed clear
What is fermentation?
The conversion of a carbohydrate, such as sugar, to acid or alcohol
What did Eduard Buchner discover?
Discovered that enzymes carry out fermentation
What did Pasteur’s work with spoiled wine lead to?
Germ Theory of Disease
How did Girolamo Fracastoro Bassi contribute to microbiology?
Proposed the idea that disease was spread by tiny infected particles
What did Robert Koch discover?
First to prove that bacteria caused disease
What are some of Robert Koch’s other contributions ?
Simple staining techniques and the use of Petri dishes
What did Ignaz Semmelweis propose?
Promoted handwashing during childbirth, using chlorine
How did Joseph Lister contribute to microbiology?
First to create an antiseptic surgical technique and use phenol to disinfect surgical tools
What did Florence Nightingale do?
Introduced antiseptic technique and hygiene in the hospital, and into the school of nursing
What did John Snow do?
Mapped Cholera cases and found it was spread by contaminated drinking water, rather than bad air
What did Edward Jenner discover?
Cowpox material provides humans with immunity from smallpox, creating the first vaccine
What is a vaccine?
A suspension of live or inactivated microorganisms
What did Louis Pasteur do for vaccines?
Weakened bacteria as a vaccine for fowl cholera
What is chemotherapy?
Treatment of disease using chemicals
What did Paul Ehrlich do for chemotherapy?
Used Compound 606- salvarsan to treat syphillis
What did Alexander Fleming discover?
Discovered the first antibiotic, penicillin, from mold Penicillium