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Unique characteristics of asthma
episodic, eosinophil driven, ICS is good for this
unique characteristics of COPD
irreversible, caused by noxious stimuli, neutrophil driven response, ICS not as good, bronchodilators good
Sx of asthma exacerbation
wheezing, chest tightness, cough, decreased lung function
Sx of COPD exacerbation
dyspnea, cough, sputum
Causes of COPD exacerbation
viral infection, bacterial infection, air pollution
Causes of asthma exacerbation
viral infection, allergens, air pollution, seasonal changes, poor ICS adherence
Risk factors for asthma related death
recent hospitalization, no ICS/poor adherence, OCS use, over-use of SABAs, no action plan, psychiatric conditions, food allergies
General treatment for Asthma exacerbation
SABA, systemic OCS, O2; SAMA, magnesium, ICS in emergent situations
General treatment of COPD
SABA/SAMA, systemic OCS, O2, antibiotics in emergent situation
Symptoms for Mild/Moderate asthma exacerbation classification
Talks in phrases, prefers sitting to lying, not agitated, RR increased, accessory muscles not used, Pulse 100-120, O2 sat 90-95%, PEF > 50%
Symptoms for Severe Asthma Exacerbation Classification
Talks in words, sits hunched forward, agitated, RR > 30, accessory muscles used, Pulse >120, O2 sat less than 90, PEF less than 50%
Treatment for mild/moderate asthma exacerbation in the primary care setting
4-10 puffs of SABA every 20 minutes for 1 hour, prednisolone, O2 if available or needed
Prednisolone dosing
1 mg/kg daily max of 50 mg in adults, 1-2 mg/kg daily max of 40 mg in children
Treatment for Severe asthma exacerbation in primary care setting
transfer to acute care facility, give SABA and ipratropium, O2, systemic corticosteroid while waiting
Treatment for mild/moderate asthma exacerbation in acute care setting
SABA, consider ipratropium, O2, oral corticosteroids
Treatment for severe asthma exacerbation in acute care setting
SABA, ipratropium, O2, oral/IV corticosteroids, consider IV magnesium, consider high dose ICS
Review Asthma/COPD from ILE 2 (OK)
OK
Treatment for COPD exacerbation
SABA/SAMA, systemic corticosteroids, antibiotics in certain cases, oxygenation via nasal cannula or mechanical ventilation
What consideration is made with SABAS in ECOPD treatment?
They can cause tachycardia/arrhythmias, drop to SAMA only if issues arise
Dosing of systemic corticosteroids in ECOPD
Prednisone 40 mg qd x 5 days
What symptoms does a patient have to make antibiotics indicated for ECOPD?
yellow/green and thick sputum, increased sputum volume, increase dyspnea
What antibiotics are most common for ECOPD
Azithromycin, Doxycycline, Augmentin; Pip/tazo, cefepime in severe cases