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What is Life
A state of chemical balance (homeostasis) that reproduces and evolves over generations
Charecteristics of life
SNR GERMS → Specific organisation, nutrition, reproduction, growth, excretion, respriation, movement, sensitive to surroundings
Recall structural levels of organisation
Molecules, cells, tissues, organs, organ systems, organisim
Epithelial tissue
tightly packed cells
covers surfaces and lines internal surfaces.
Protection, secretion and absorbtion
example of epithelial tissue
Epidermis of skin
Lining of blood vessles
lining of intestines
types or epithelial tissue (layers)
simple, stratified, cuboidal, columnar, or squamous.
connective tissue
loosely packed cells
obvious matrix
examples of connective tissue
cartlidge, bone, blood, fat
muscular tissue
elongated and can contract
types of muscle tissue
skeletal, cardiac, smooth
skeletal muscle tissue
attatched to bone
striated
stripey
volentary movement
cardiac muscle tissue
in heart
is striated
stripey
involuntary
smooth muscle tissue
in walls of hollow organs
not striated
involuntary
nervous tissue
very irregular shape
sense stimuli
transmit signals
support glial cells
define tissue
a group of specialised cells (and cell products) that work together for a particular function
cell theory
all organisims are made up of 1 or more cells
all cells come from pre-existing cells
cells are the smallest organisational (structural and functional) unit of life
2 major cell types
prokaryotic and eukaryotic
Eukaryotic and prokaryotic similar features (4)
cell membrane, cytoplasm, ribosomes, DNA
role of cytoplasm
jelly like material which organelles float in
chemical reactions occur here
role of nucleus
contains genetic material
cell’s control center
role of nucleolus
production and assembly of rRNA
role of ribosomes
site of protein production
role of cell membrane
selectively permiable barrier which controls what enters and leaves the cell
role of cell wall
provides support strength and protection to plant cells
role of rough endoplasmic reticulum (rough ER)
transport of proteins and lipids
role of smooth endoplasmic reticulum (ER)
transport of proteins and lipids
difference between Rough ER and Smooth ER
Rough ER has ribosomes attatched and smooth ER does not
role of Golgi Apparatus (golgi body)
protein packaging after recieved from ER
role of lysosomes
waste removal
role of centrioles
direct chromosome movement during cell division
role of vacuoles
storage of water and nutrients
difference between vacuoles in plant and animal cells
plant cells have 1 large vacuole, animal cells have many small vacuoles
role of mitocondria
site of cellular respiration and energy production
role of chloroplasts
site of photosynthesis in plant cells
types of microscopes (3)
light, compound, electron
electron microscope
large magnification
very good resolution
specimen must be dead
advantage of compound light microscope
affordable
disadvantage of compound light microscope
max resolution of 2um
advantage of electron microscope
x2,000,000 magnification
disadvantage of electron microscope
expensive
features of good biological drawing
Draw what is seen (to a large size eg. A5)
Use a sharp pencil
Position drawing in the centre of page
Clear lines not sketchy and shapes complete.
Don’t shade, (stippling may be used)
Labels – on right, with horizontal lines, not crossing
Include title, magnification of drawing, names of structures
Diameter field of view formula
field number (18)/objective magnification
what is 1mm equial to in um
1,000 micrometers
real life size formula
diameter field of view/number of cells that fit across field of view
magnification of drawing formula
size of drawing (um)/real life size (um)
which photosynthetic pigment is the most important
chlorophyll A
why is chlorophyll A green
reflects alot of green light and absorbs mainly blue and red wavelengths.
which colour has longest wavelenglth
red
which colour has the shortest wavelegth
violet
factors affecting rate of photosynthesis (4)
light intensity levels
co2 levels
temperature
water availability
define phototaxis
movement of an organism toward or away from a light source
exampls of a phototaxic organisim
euglena
photosynthesis word equation
carbon dioxide + water → glucose + oxygen
photosynthesis chemical equation
6CO2 + 6H2O → C6H12O6 + 6O2
where does photosynthesis take place
chloroplasts
name the 2 stages of photosynthesis
light dependant reaction, light independent reaction
where does the light dependent reaction take place
grana (thylakoid discs) inside chloroplasts
what happens in light dependent reaction
chlorophylls absorb solar energy and split water into hydrogen (NADPH2/NADP) and oxygen, as well as producing some ATP molecules
where does the light independent reaction occur
stroma inside chloroplasts
what happens in light independent reaction
ATP is used to combine carbon and oxygen with hydrogen to produce triose phosphate
what is the light independent reaction otherwise known as
calvin cycle
enzyme important to the light independant reaction
RUBISCO
what are triose phosphate molecules combined to form?
glucose
what is glucose combined to form
starch (for storage)
what is a disease
abnormal condition of an organisim which interrupts normal bodily functions
define a sign
somthing that can be measured by another individual
example of a sign
a temperature
rash
define a symptom
somthing that can be experioenced only by the individual
example of a symptom
pain
nausea
fatigue
major differencating factor between non infectious and infectious disease
non infectious disease are not caused by pathogens
virulence
the ability for a pathogen to cause disease
6 major groups of pathogens
prions
viruses
bacteria
fungi
protozoa
multicellular parasites
example of prion
mad cow disease
what does a prion do?
misfold proteins that damage the brain
example of a virus
influenza
example of bacteria
strep throat
example of fungi
athletes foot
example of protozoa
maleria
example of multicellular parasite
tapeworm
how can disease be spread (5)
direct contact
contact with body fluids
contaminated food
water
vector organisims
what does a vaccination involve
weakened or killed pathogen (or antigens) to stimulate an immune response
what can antibiotics be used for
bacterial infection
what can antifungal medication be used for
fungal infection
what can antiviral medication be used for
viral infection
what is in the first line of defence
physical and chemical barriers
examples of first line of defence
skin
enzymes
mucous secretion
goal of first line of defence
prevent disease entry to body
what does the second line of defence involve
phagocytic white blood cells (neutrophils and macrophages)
physical traits from second line of defence
infammation at site of infection
what do macrophages do
‘eat’ foreign cells/pathogens
what does the third line of defence involve
immune system specific white blood cells (lymphocytes)
major divisions of the third line of defence
cellular and homoral immunity
what type of blood cells are used in cellular immunity
T Lymphocytes
what do t lymphocytes do
enlarge and divide to kill pathogen
where do t lymphocytes mature
thymus gland
what type of blood cells are used in humoral immunity
B Lymphocytes
where do b lymphocytes mature
bone marrow
what do b lymphocytes replicate to become
plasma cells
where are antibodies and antigens used
3rd line of defence
define antigen
a molecule found on surface of pathogens which promote a specific immune responce