BMS220 Drug Deckade 4

Atorvastatin: Indication

Hyperlipidemia

Atorvastatin: Brand name

Lipitor

Atorvastatin: MOA

HMG-CoA reductase inhibitor

Atorvastatin: ADR

GI, neuromuscular, respiratory

Atorvastatin: BW

n/a

Atorvastatin: DI

Muscle weakness

Tramadol: Indication

Pain

Tramadol: Brand names

ConZip, Qdolo, Ultram

Tramadol: MOA

Analgesic/opioid

Tramadol: ADR

CNS, GI

Tramadol: BW

Respiratory depression

Tramadol: DI

Xerostomia, changes in salivation

Escitalopram: Indication

Depression

Escitalopram: Brand name

Lexapro

Escitalopram: MOA

Selective serotonin reuptake inhibitor

Escitalopram: ADR

CNS, GI

Escitalopram: BW

Suicidal thoughts

Escitalopram: DI

Xerostomia, toothache

Hydrochlorothiazide + Lisinopril: Indication

Hypertension

Hydrochlorothiazide + Lisinopril: Brand name

Zestoretic

Hydrochlorothiazide + Lisinopril: MOA

Diuretic + ACE inhibitor

Hydrochlorothiazide + Lisinopril: ADR

CV, CNS

Hydrochlorothiazide + Lisinopril: BW

Fetal toxicity

Hydrochlorothiazide + Lisinopril: DI

Orthostatic hypotension, dizziness

Lisinopril: Indication

Hypertension

Lisinopril: Brand names

Prinivil, Qbrelis, Zestril

Lisinopril: MOA

ACE inhibitor

Lisinopril: ADR

CV, CNS, renal

Lisinopril: BW

Pregnancy

Lisinopril: DI

Orthostatic hypotension, dry cough

Simvastatin: Indication

Hyperlipidemia

Simvastatin: Brand names

FloLipid, Zocor

Simvastatin: MOA

HMG-CoA reductase inhibitor

Simvastatin: ADR

GI, CNS, respiratory

Simvastatin: BW

n/a

Simvastatin: DI

Muscle weakness

Omeprazole: Indication

Reflux disease, ulcer

Omeprazole: Brand name

Prilosec

Omeprazole: MOA

Proton pump inhibitor

Omeprazole: ADR

CNS, GI, carcinoma

Omeprazole: BW

n/a

Omeprazole: DI

Dysgeusia, dry mouth, candidiasis

Metoprolol: Indication

Hypertension

Metoprolol: Brand names

Kapspargo Sprinkle, Lopressor, Toprol XL

Metoprolol: MOA

Beta blocker

Metoprolol: ADR

CV, dermatologic

Metoprolol: BW

Ischemic heart disease on withdrawal

Metoprolol: DI

Reduced efficacy with long-term NSAID use

Albuterol: Indication

Asthma

Albuterol: Brand names

ProAir, Proventil, Ventolin

Albuterol: MOA

Beta-2 agonist

Albuterol: ADR

Respiratory, CNS, neuromuscular

Albuterol: BW

n/a

Albuterol: DI

Xerostomia

Hydrochlorothiazide: Indication

Hypertension

Hydrochlorothiazide: Brand name

Microzide

Hydrochlorothiazide: MOA

Diuretic

Hydrochlorothiazide: ADR

CV, endocrine

Hydrochlorothiazide: BW

n/a

Hydrochlorothiazide: DI

Orthostatic hypotension

Losartan: Indication

Hypertension

Losartan: Brand name

Cozaar

Losartan: MOA

Angiotensin II receptor blocker

Losartan: ADR

CV, CNS, respiratory

Losartan: BW

Pregnancy

Losartan: DI

Orthostatic hypotension

Furosemide: Indication

Hypertension

Furosemide: Brand name

Lasix

Furosemide: MOA

Loop diuretic

Furosemide: ADR

CV, endocrine

Furosemide: BW

Electrolyte loss

Furosemide: DI

Orthostatic hypotension

Atenolol: Indication

Hypertension

Atenolol: Brand name

Tenormin

Atenolol: MOA

Beta blocker

Atenolol: ADR

CV, CNS

Atenolol: BW

Ischemic heart disease on withdrawal

Atenolol: DI

Reduced efficacy with long-term NSAID use

Fluoxetine: Indication

Depression

Fluoxetine: Brand names

Prozac, Sarafem

Fluoxetine: MOA

Selective serotonin reuptake inhibitor

Fluoxetine: ADR

CNS, GI

Fluoxetine: BW

Suicidal thoughts

Fluoxetine: DI

Xerostomia, dysgeusia, bruxism, increased bleeding with NSAID or warfarin

Citalopram: Indication

Depression

Citalopram: Brand name

Celexa

Citalopram: MOA

Selective serotonin reuptake inhibitor

Citalopram: ADR

CNS, GI

Citalopram: BW

Suicidal thoughts

Citalopram: DI

Xerostomia, abnormal taste

Trazodone: Indication

Depression

Trazodone: Brand names

APO-Trazodone, JAMP-Trazodone, TEVA-Trazodone

Trazodone: MOA

Selective serotonin reuptake inhibitor

Trazodone: ADR

CNS, GI

Trazodone: BW

Suicidal thoughts

Trazodone: DI

Significant xerostomia

Fluticasone: Indication

Asthma maintenance control, rhinitis, chronic rhinosinusitis

Fluticasone: Brand names

ArmonAir, Flonase, Flovent, Ticaspray, Xhance

Fluticasone: MOA

Corticosteroid

Fluticasone: ADR

CNS, respiratory - sinusitis