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Vocabulary flashcards covering major terms related to neuronal structure, function, spinal cord anatomy, nerve physiology, reflexes, autonomic pathways, and clinical conditions from Chapter 9.
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Central nervous system (CNS)
The brain and spinal cord; acts as the body’s primary control and integration center.
Peripheral nervous system (PNS)
All nervous tissue outside the CNS; includes cranial and spinal nerves.
Somatic nervous system
Division of the PNS that provides voluntary control of skeletal muscles.
Autonomic nervous system (ANS)
Involuntary motor division of the PNS that regulates glands, smooth muscle, and cardiac muscle.
Sympathetic nervous system
ANS division that produces the fight-or-flight stress response.
Parasympathetic nervous system
ANS division that promotes rest-and-digest (SLUDD) functions and conserves energy.
Neuron
The functional nerve cell that transmits electrical impulses.
Cell body (soma)
Portion of a neuron containing the nucleus and most organelles.
Dendrite
Branchlike neuron process that carries impulses toward the cell body.
Axon
Long neuron process that carries impulses away from the cell body.
Myelin sheath
Fatty insulating covering around many axons that speeds impulse conduction.
Schwann cell
PNS glial cell that forms myelin and the neurilemma around peripheral axons.
Oligodendrocyte
CNS glial cell that forms myelin sheaths around central axons.
Node of Ranvier
Gap between adjacent myelin segments where action potentials occur.
White matter
CNS tissue composed mainly of myelinated axons.
Gray matter
CNS tissue made of neuron cell bodies and unmyelinated fibers.
Sensory (afferent) neuron
Neuron that carries impulses from receptors toward the CNS.
Motor (efferent) neuron
Neuron that carries impulses from the CNS to muscles or glands.
Interneuron
Neuron located within the CNS that connects sensory and motor pathways.
Nerve
Bundle of axons (fibers) in the PNS surrounded by connective tissue.
Tract
Bundle of axons located within the CNS.
Endoneurium
Delicate connective tissue surrounding each individual nerve fiber.
Perineurium
Connective tissue wrapping that surrounds a fascicle (axon bundle) in a nerve.
Epineurium
Outermost connective tissue layer enclosing an entire nerve.
Ganglion
Collection of neuron cell bodies located outside the CNS.
Plexus
Network of intersecting spinal nerves that redistribute fibers to peripheral nerves.
Dermatome
Skin region supplied by a single spinal nerve.
Action potential
Rapid, self-propagating change in membrane potential used to transmit a nerve impulse.
Resting membrane potential
−70 mV charge difference across a neuron membrane when unstimulated.
Depolarization
Phase of an action potential when the membrane potential becomes less negative.
Repolarization
Return of the membrane potential toward resting levels after depolarization.
Hyperpolarization
Membrane potential becomes more negative than the resting level.
Saltatory conduction
Jumping of action potentials between Nodes of Ranvier on a myelinated axon.
Synapse
Junction where a neuron communicates with another cell via neurotransmitters.
Neurotransmitter
Chemical messenger that carries signals across a synaptic cleft.
Acetylcholine (ACh)
Primary cholinergic neurotransmitter; released at neuromuscular junctions and many ANS synapses.
Norepinephrine (NE)
Adrenergic neurotransmitter released by most sympathetic postganglionic neurons.
Nicotinic cholinergic receptor
ACh-binding receptor on skeletal muscle cells and all ANS ganglionic neurons.
Muscarinic cholinergic receptor
ACh-binding receptor on parasympathetic target organs and all postganglionic ANS neurons.
Adrenergic receptor
Receptor that binds epinephrine or norepinephrine on sympathetic target cells.
Reflex arc
Pathway from receptor to effector producing an automatic response.
Stretch reflex
Simple reflex that contracts a muscle in response to being stretched (e.g., knee-jerk).
Withdrawal reflex
Protective reflex that pulls a body part away from painful stimuli.
Cerebrospinal fluid (CSF)
Clear fluid that cushions the CNS; fills the ventricles and central canal.
Lumbar puncture
Procedure that removes CSF from the subarachnoid space for analysis.
Epidural
Injection of anesthetic into the epidural space around the spinal cord.
Multiple sclerosis (MS)
Autoimmune demyelinating disease of CNS neurons leading to sensory and motor deficits.
Neuropathy
Any disorder or disease affecting peripheral nerves.
Carpal tunnel syndrome
Mononeuropathy caused by compression of the median nerve in the wrist.
Phrenic nerve
Cervical plexus nerve that innervates the diaphragm and controls breathing.