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Epidemiology
The study of the frequency, distribution, and determinants of health problems and disease in human populations.
Incidence
The number of NEW CASES of disease that develop in a population of individuals at risk during a specified time period.
Prevalence
The total number of EXISTING CASES of disease in a population at one point in time.
Descriptive Epidemiology (incidence & prevalence)
used to describe a health problem. Characterize the amount and distribution of a disease.
• What, when, where, and who of a condition
• Person, place, time
Analytical Epidemiology
ften follow descriptive studies: used to determine the cause of a health problem.
• Explains the “why” of a condition
• Agent, host, environment
p-value = confidence
Public Health Action
Strategies implemented based on epidemiological findings to promote health and reduce disease.
Surveillance in Epidemiology
The continuous, systematic collecting, analysis, interpretation, and dissemination of data regarding a health-related event.
Geographic Patterns
Patterns observed in health data that can indicate locations with higher or lower incidence of a health problem.
Determinants of Health
Factors that influence health outcomes, including biological, socio-economic, and environmental factors.
TIME, PLACE, PERSON
Time: When events occurred (diagnoses, reporting, testing)
Trends, seasonal variations, cohort effects…
Place: Geography of the affected individuals
Variations between geographical areas – local, national, international…
Person: Charactertists of the individual affected by the outcome.
Variations in health by age, sex, ethnicity, occupation, leisure interests etc
data collection
type of data
reporting
what to do with the data
analysis
what kind of analysis we get from the data
response
intervention and targeting
Analytical Epidemiology (causal claims)
descriptive epiedemiology + Analysis of cause and effect
types of analytical studies
observational
cross-sectional study
descriptive or analytical
case control study
cohort study
intervention study/ experimentation
randomized controlled trial (RCT)
John Snow
Physician known for his work in epidemiology, particularly in mapping cholera outbreaks in London.
Miasma Theory
The hypothesis that diseases such as cholera were caused by 'bad air' or toxic vapors.
Cohort Study
follows two groups over time to compare the occurrence of disease based on exposure to risk factors.
Randomised Controlled Trial (RCT)
Compares effectiveness of a new intervention against the best current alternative (or a placebo
Case-Control Study
Compares people with a condition (cases) to a similar group of people without the condition (controls)
Cross-Sectional Study
Information on health status and other characteristics is collected from each subject at one point in time
Bradford Hill's Criteria for Causation
1. Strength of association
2. Temporal relationship
3. Geographical distribution
4. Dose-response relationship
5. Consistency of results
6. Biological plausibility (but remember John Snow)
7. Specificity (if a single causal agent)
8. Reversibility
Selection Bias
A form of bias that occurs when the sample chosen for a study is not representative of the population.
Public Health
It allows the distribution of health and unhealthy in a
population to be described, and possible causal
factors to be identified.
Epidemiological Association
The relationship between a risk factor and a health outcome, which does not automatically imply causation.
Biological Plausibility
The consistency of epidemiological findings with existing biological knowledge regarding disease mechanisms.
Interpreting results of analytical studies
is there association or not
Polysomnography (PSG)
A comprehensive sleep study used to diagnose sleep disorders, involving monitoring various physiological parameters during sleep.
Circadian Rhythm Disorders
jet lag and shift work
Sleep disorders that occur due to misalignment between an individual’s biological clock and external demands on the sleep cycle.
Insomnia Disorder
is dissatisfaction with sleep, characterized by difficulty falling asleep, difficulty maintaining sleep, or difficulty returning to sleep after awakenings during the night
(at least 3 nights per week for at least three months.)
difficulty falling, staying and returning to sleep
Narcolepsy
extreme daytime sleepiness, marked by recurrent episodes of an irresistible need to sleep, unintentional sleep episodes, or napping. (at least 3 times per week for at least 3 months)
Parasomnias
Disruptive sleep disorders involving abnormal behaviors during sleep, such as sleepwalking, night terrors, and sleep talking.
Electroencephalogram (EEG)
most informative
measures the electrical changes in the brain. the electrodes are placed on the scalp.
Multiple Sleep Latency Test (MSLT)
A test designed to measure daytime sleepiness by assessing how quickly a person falls asleep in a series of short naps.
Hypersomnolence Disorder
A condition characterized by excessive sleepiness despite adequate sleep, affecting daily functioning.
Restless Legs Syndrome
A condition involving uncomfortable sensations in the legs and an irresistible urge to move them, often disrupting sleep.
Sleep-disordered Breathing (Sleep Apnea)
A disorder characterized by repeated interruptions in breathing during sleep, leading to fragmented sleep and excessive daytime sleepiness.
when are sleep disorders considered pathological?
if it negatively impacts your day-day life - if it doesn’t it’s just a sleep disturbance
Electrooculogram (EOG)
eye movement
measures the electrical changes as the eyes rotate in its socket. The electrodes are placed either above and below the eye or left and right of the eye.
Electromyogram (EMG)
muscle tension
measures the electrical changes generated during muscle contraction. The electrodes are placed under the chin.
multiple sleep latentcy test (MSLT)
Actigraphy
Actigraphy
It is a relatively non-invasive method of monitoring human rest/activity cycles
2 Categories of Sleep Disorders
are dyssomnias and parasomnias.
dyssomnia
Problems in the timing of sleep
Complaints about the quality of sleep
entrance into sleep
insomnia
parasomnias
Abnormal behavioral & physiological events during sleep
e.g. nightmares, sleep walking, sleep talking
effects sleeping
narcolepsy requires one of three additional findings:
episodes of cataplexy - sudden loss of muscle tone
hypocretin - (low orexin)
reduced latency to REM - 15 minutes or less
hypnagogic
hallucinations occurring at sleep onset, often experienced during the transition from wakefulness to sleep.
hypnopompic
hallucinations occurring upon waking, often occurring during the transition from sleep to wakefulness.
night terrors
3-4
somnambulism
3 & 4
principles of sleep hygiene
• Sleep in cool, quiet, comfortable place.
• Keep regular sleep-wake schedule.
• When having trouble sleeping at night, avoid daytime
naps.
• Exercise < 4hrs before bed.
• Avoid caffeine, food close to bedtime.
• Make bed a restful heaven for sleep.
• Don’t worry about not getting enough sleep .
• Change sleeping place, if unable to sleep.
Canada Health Transfer
- health related services
- extra billing not permitted
Canada Social Transfer
- provinces & territories
- Child care, post secondary
Territorial Formula Financing
unique geography
-just territories
Federal Health Transfer Payments
- house use: 30% of health care Spending = consumer's pockets/insurance
- based on distribution
what is Canada's health care system?
a group of socialized health insurance plans
-provides coverage to all Canadian citizens
is the Canadian Health Care system publicly funded?
Yes, it is publicly funded
Who administers Canadian Health Care system?
provincial or territorial basis, within the guidlines set by the federal government.
Health Care Funding
The care received is specific to each province or territory
- provided via taxation (personal or corporate)
- sales tax and lottery or proceed
Funded at both the provincial and federal levels
What is a for-profit organization?
Formed to make money, or profits, by offering products or services
ex: retail stores, restaurants
- maximize capital gain
ex: food and meal prep, maintenance, cleaning/Laundry, security
What is a non-for-profit organization?
An organization set up for a purpose other than profit
The money that is made goes back to the program
- minimize capital gain
- subsidized
How are hospitals funded?
privately but non-for-profit organization
How are Physicians (unless salaried) funded
they are paid through the hospitals
Consumer Health Products
cover a broad range of products that are defined and organized by health canada.
qualified health claim
is supported by scientific evidence but does not achieve the "significant scientific agreement" standard.
Health claim
a relationship between a food and a reduced risk of a disease or a health-related condition.
authorized health claim
regulatory bodies has authorized for use based on "significant scientific agreement" on the subject.
Nutrient Content Claims
describe the level of a nutrient in a food.
Structure/Function Claims
describe the role of a nutrient or ingredient on the structure or function of the human body
consumer health products
Non-prescription drugs (e.g., pain relievers, cold and allergy remedies, acne therapies);
Disinfectants (e.g., for use on countertops, contact lens solution);
Cosmetics (e.g., make-up, shampoos, deodorants); and
Natural health products (e.g., vitamin and mineral supplements, traditional and homeopathic medicines, probiotics, toothpastes).
consumer health products guiding principles
• protecting the health and safety of Canadians;
• a science-based approach;
• transparency of important product information;
• proportional oversight for products, both pre- and post-market;
• flexibility to address varying risk profiles;
• international alignment;
• operational efficiency and sustainability;
• responsive regulatory approach; and
• reduction and prevention of regulatory barriers to small businesses.
Complementary and Alternative Medicine (CAM)
Medical products and practices that are not part of standard medical care.
Conventional Medicine
Health treatment administered by professionals who hold an M.D. or D.O. degree, often using drugs, radiation, or surgery.
manages symptoms of disease and focuses on healing at the organ level. but it does not fix the root cause and neglets system level
Integrative Medicine
focuses in healing the individuals as a whole. uses the best evidence-based therapies available.
Holistic Approach
A view that considers the whole person—physical, mental, emotional, and spiritual—in treatment.
Alternative Medicine
Non-mainstream practices used as replace conventional medical care.
Mind-Body Therapies
Practices based on the premise that the mind influences the body in ways that affect well-being.
Energy Therapies
Therapies based on the idea that a disruption or imbalance of energy can lead to illness.
Standard of Care
Treatment that is accepted by medical experts and widely used by healthcare professionals for a specific disease.
CAM Users Statistics
Approximately 42% of people in the U.S. have used CAM at least once in the last 5 years.
Conventional vs. CAM
Conventional medicine often focuses on symptom management, while CAM may focus on healing the body as a whole.
Major Deciding Factor in Health Care Choices
Insurance status which affects the management of chronic conditions.
Herbal Products
Plant-derived substances used in therapies that fall under the CAM category.
Patient-Provider Communication
Critical exchange where 40-70% of CAM users do not disclose their CAM use to physicians.
Mind-Body Therapy Examples
Meditation, yoga, biofeedback, and hypnotherapy are among the practices that demonstrate this approach.
Technological Influence on Health
The impact of new technology on health outcomes and patient interactions.
what is medicine
diagnostic treatment
what is interdrated medicine?
looking at the body through a different lens.
mental, social, rather than genes
neuropathy
nerves dying resulting in pain or loss of function.
peripheral
pain in fingers and toes
tendonitis
inflammation
who needs to approve Complementary Medicines
the royal collage of surgeons, if not its considered alternative medicine
which two types of medicine is CAM against
alternative and complementary medicine
functional medicine
addresses functional imbalances underlying illness and promotes optimal health function
homeopatic treatment
no bio in it.
which natural substance has anti-cancer properties?
curcumin, tumeric
photodynamic therapy
uses light to change a molecualr process. alters metabolism
photothermal therapy
using high energy light to heat and damage tissue, to decrease inflammation after an injury.
Cancer
A disease caused by an uncontrolled division of abnormal cells in a part of the body.