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KPE260
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the 1st step in the lipid-soluble hormone pathway
hormone diffuses through the plasma membrane
After entering the cell, what happens next?
the hormone binds an intracellular receptor (cytoplasmic or nuclear)
what forms after the hormone binds the receptor
receptor-hormone complex
where does the receptor-hormone complex go?
into the nucleus
what does the complex do inside the nucleus
alters gene transcription
what happens after transcription
mRNA is produced
what does mRNA do
leaves nucleus, gets translated into protein
what is the final result of the lipid-soluble pathway
new protein changes cell activity (genomic response)