Numerical Chromosomal Abnormalities and Nondisjunction

A collection of vocabulary flashcards covering key terms and definitions related to numerical chromosomal abnormalities and nondisjunction.

Trisomy

A chromosomal abnormality involving three copies of a single chromosome.

Monosomy

A chromosomal abnormality involving one copy of a single chromosome.

Triploidy

A chromosomal abnormality characterized by three complete sets of chromosomes (3N).

Tetraploidy

A chromosomal abnormality characterized by four complete sets of chromosomes (4N).

Nondisjunction

The failure of chromosomes to separate normally during cell division.

Spontaneous abortion

The natural termination of a pregnancy, often due to chromosomal abnormalities.

Down Syndrome

A condition caused by trisomy of chromosome 21, often resulting from nondisjunction.

Chromosomal abnormalities

Changes in the structure or number of chromosomes that can lead to various disorders.

Centromere-linked marker

A genetic marker associated with the centromere, used to study nondisjunction events.

XXY

A male with Klinefelter syndrome, characterized by the presence of an extra X chromosome.