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What identifies a drug’s atomic and molecular structure?
Chemical name
What name is assigned by the manufacturer who first develops the drug?
Generic name
What is the name used in official publications, typically the generic?
Official name (monograph)
What is the copyrighted brand name?
Trade name
Give examples of oral drug forms.
Capsule, pill, tablet, extended release, elixir, suspension, syrup
Give examples of topical drug forms.
Liniment, lotion, ointment, suppository, transdermal patch
Give examples of parenteral preparations.
Injectable, infusion, implantation
Which drug preparation is a clear liquid with water, alcohol, sweeteners, and flavor?
Elixir
What is a suspension?
Finely divided, undissolved particles in a liquid medium
What is a solution?
A drug dissolved in another substance
What is a syrup?
Medication combined with water and sugar solution
How are drugs classified?
By body system effect, chemical composition, or clinical indication/therapeutic action
What does pharmaceutical class refer to?
Mechanism of action (MOA), physiologic effect (PE), chemical structure (CS)
What does therapeutic class refer to?
Clinical indication or therapeutic action (e.g., analgesic, antibiotic, antihypertensive)
What are the four processes of pharmacokinetics?
Absorption, Distribution, Metabolism, Excretion
List six factors that affect absorption.
Route of administration, lipid solubility, pH, blood flow, local conditions at site, drug dosage
Define pharmacodynamics.
Process by which drugs alter cell physiology and affect the body
What are ways drugs act on the body?
Turn on/off processes, promote/block responses
What happens during a drug–receptor interaction?
Drug interacts with cellular structures to alter function
How else may drugs achieve effects?
Combine with molecules, act on cell membrane, or alter environment
List 6 types of adverse drug reactions.
Side effects, allergic effects (anaphylaxis), drug tolerance, toxic effect, idiosyncratic effect, drug interactions
Name two types of drug interactions.
Antagonistic and synergistic
List factors that affect how drugs act.
Developmental stage, weight, biologic sex, cultural/genetic (ethnopharmacology), psychological factors, pathology, environment, timing of administration
What is the therapeutic range?
Drug concentration that produces desired effect without toxicity
What is the peak level?
Highest plasma concentration
What is the trough level?
Lowest concentration, shows elimination rate
What is the half-life of a drug?
Time for 50% of blood concentration to be eliminated
What is a standing order?
Routine, carried out until canceled
What is a PRN order?
As needed
What is a single/one-time order?
Medication given once only
What is a stat order?
Medication given immediately
What are the required parts of a med order?
Patient name, date/time written, drug name, dosage, route, frequency, prescriber signature
True/False: Pain medications may be given without an order.
False – No medication may be given without a licensed practitioner’s order
List five types of supply systems.
Stock supply, individual unit dose, medication cart, computerized system, BCMA (bar code–enabled cart)
Which system keeps large quantities on the unit?
Stock supply
Convert 1 kilogram → grams.
1,000 g
Convert 1 gram → milligrams.
1,000 mg
Convert 1 milligram → micrograms.
1,000 mcg
Convert 1 liter → milliliters.
1,000 mL (cc)
1.5 grams = ? mg
1,500 mg
What are the three checks for medication administration?
When reaching for container/unit dose
After retrieval, before pouring/administration
Before giving/replacing container
Name the 5 basic rights.
Right medication, patient, dosage, route, time
Name the 5 additional rights.
Right reason, assessment data, documentation, response, education, refusal
What info must be documented for controlled substances?
Patient name, amount, hour, provider, nurse
Name two identifiers.
Name + ID number/record number/DOB
How do you confirm identity?
ID bracelet, eMAR comparison, asking patient to state name
Subcutaneous
adipose tissue
Intramuscular
muscle (ventrogluteal/deltoid recommended; dorsogluteal not recommended)
Intradermal
just under epidermis (sensitivity tests, small dose <0.5 mL, 26–27 gauge, 5–15°)
Intravenous
bloodstream, immediate
Topical routes?
Skin, eye, ear, nasal, vaginal, rectal
Criteria for choosing equipment?
Route, viscosity, quantity, body size, type of medication
Angles of insertion? Intradermal
5–15°
Angles of insertion? Subcutaneous
45–90°
List ways meds come for injection.
Ampules, vials, prefilled syringes, cartridges, reconstituted powders
Angles of insertion? Intramuscular
90°
Can insulins be mixed?
Yes, in one syringe (per rules)
What must be charted after administration?
Drug name/dosage, route/time, administrator’s name, site used, location (topical/transdermal), naris/eye/ear, omitted/refused drugs, errors
Examples of errors?
Wrong patient, wrong dose, wrong route, wrong time, wrong prep, improper technique, deteriorated drug, prescribing errors
What steps after error?
Check patient & observe, notify provider/manager, complete error report
What must be taught to patients?
How to administer meds
Take meds as prescribed, full duration
Do not alter dosage without physician
Do not share meds