Hallucinogens

hallucination

a sensory perception (visual, auditory, tactile, olfactory, gustatory) that occurs in the absence of corresponding external stimulation or reality

indolamine hallucinogens

a class of hallucinogenic drugs that share a similar chemical structure to the neurotransmitter serotonin (5-HT), LSD, psilocybin, and DMT

5-HT2A receptor

a subtype of serotonin receptor in the brain that is believed to play a cruical role in mediating the effects of indolamine hallucinogens

agonist

a substance that binds to a receptor and activates it, producing a biological response

cross-tolerance

tolerance to one drug resulting in tolerance to another drug that acts through a similar mechanism

ergotism

a condition caused by consuming grains contaminated with ergot fungus, historically associated with hallucinations and other physical symptoms

lysergic acid diethylamide (LSD)

a potent semisynthetic idolamine hallucinogen first synthesized by Albert Hofmann

psilocybin

a naturally occurring idolamine hallucinogen found in certain species of mushrooms

ayahuasca

a psychoactive brew traditionally used in South American, often containing DMT and MAO inhibitors

phantastican effects

the aspect of hallucinogenic experiences characterized by feelings of profound significance, insight or revelation

entactogenic effects

effects that enhance self-awareness and ability to access previously hidden memories or emotions

empathogenic effects

effects that enhance feelings of empathy, emotional openness, and connection with others

hallucinogen persisting perception disorder (HPPD)

a condition characterized by the re-experience of visual or other sensory disturbances that are reminiscent of those experienced during hallucinogen intoxication, occurring long after the drug has been eliminated from the body

serotonin syndrome

a potentially life-threatening condition resulting from excessive serotonin activity in the CNS, often occurring with combinations of serotonergic drugs and MAOIs