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Fluid volume excess (hypervolemia)
Too much fluid in the body; weight gain is the most common sign
Fluid volume deficit (hypovolemia)
Too little fluid in the body; weight loss is a major indicator
Best indicator of fluid volume change
Daily body weight
1 L of water weighs how much?
2.2 lb (1 kg)
First spacing
Normal fluid distribution in the ICF and ECF
Second spacing
Abnormal accumulation of fluid in the interstitial space = edema
Third spacing
Fluid becomes trapped where it is difficult or impossible to return to the cells or blood vessels
Hyponatremia
Low sodium; associated with fluid retention
Hypernatremia
High sodium; associated with dehydration
Signs of hyponatremia
Weight gain, edema, neurologic changes (fluid retention)
Serious complications of hyponatremia
Irritability, seizures, coma
Signs of hypernatremia
Decreased urine output + neurologic changes
Serious complications of hypernatremia
Confusion, seizures, coma
Treatment for hyponatremia from excess fluid
Diuretics, fluid restriction, or 3% NaCl
Treatment for hypernatremia
Oral fluids or IV isotonic/hypotonic solution
Hyperkalemia
High potassium
Major causes of hyperkalemia
Renal failure, potassium-sparing diuretics, excessive potassium intake
Hyperkalemia mnemonic
MURDER
What does MURDER stand for in hyperkalemia
muscle cramps/tetany, urine abnormalities, respiratory distress, decreased cardiac contractility, EKG changes, reflexes
Major complication of hyperkalemia
Cardiac/EKG changes
Treatment for severe hyperkalemia
Dialysis, insulin, medication changes, sodium polystyrene sulfonate
What does IV insulin do during hyperkalemia treatment?
Moves K⁺ from the ECF into the ICF
What medication stabilizes the cardiac membrane during severe hyperkalemia?
IV calcium chloride or calcium gluconate
What monitoring is important with severe hyperkalemia?
Continuous ECG monitoring
Hypokalemia
Low potassium
Major causes of hypokalemia
Loop diuretics and poor nutrition
Hypokalemia mnemonic
7 L's
What does the 7 L’s stand for in hypokalemia
lethargy, low shallow respirations, lethal cardiac dysrhythmias, lots of urine, leg cramps, limp muscles, low BP & heart rate
Can IV KCl be given IV push?
NEVER
Can IV KCl be given as a bolus?
NEVER
What must happen before giving IV KCl?
Dilute it
Maximum IV KCl rate in this lecture
10 mEq/hr
What should be used when administering IV KCl?
Infusion pump
Foods high in potassium
Spinach, banana, fish, potato, mango, avocado, beans, strawberries
Hypercalcemia
High calcium
Major causes of hypercalcemia
Hyperparathyroidism and cancer
Hypercalcemia mnemonic
"Bones, stones, abdominal groans, psychic moans"
Complications of hypercalcemia
Dysrhythmias, seizure, coma
Treatment for hypercalcemia
Weight-bearing exercise, push fluids 3-4 L/day, bisphosphonates, calcitonin
Hypocalcemia
Low calcium
Causes of hypocalcemia from lecture
Decreased PTH, blood/diet factors, hyperventilation
Hypocalcemia mnemonic
CATS
What does CATS stand for in HYPOcalcemia
convulsions, arrhythmias, tetany, spasms/stridor
Classic signs of hypocalcemia
Positive Trousseau's or Chvostek's sign
Other signs of hypocalcemia
Numbness/tingling around mouth or extremities
Treatment for hypocalcemia
Calcium + vitamin D or IV calcium gluconate
Hypotonic solution
Causes cells to swell (HIPPO)
Isotonic solution
Causes no major cellular change
Hypertonic solution
Pulls water out of cells → cells shrink (SKINNY)
Main effect of hypotonic
Water moves into cells
Hypotonic used for
Treating hypernatremia
Nursing priority for hypotonic
Monitor neurologic status
Examples of hypotonic solutions
0.45% NS, 0.25% NS
Main effect of isotonic solutions
No major cellular change
Isotonic solution used for
Fluid volume replacement/bolus
What to monitor for isotonic solutions
monitor I&O and fluid overload
Examples of isotonic solutions
0.9% NS, Lactated Ringer's, D5W
Which IV fluid is the only solution used with blood?
0.9% normal saline
Main effect of hypertonic solution
Pulls water out of cells
Hypertonic solution used for
Replacing electrolytes
What to monitor with hypertonic solution
Electrolytes and I&O
Examples from lecture for hypertonic solutions
TPN and solutions containing Mg, Na, K, or glucose
Normal saline concentration
0.9% NaCl
Normal saline tonicity
Isotonic
When is normal saline used?
When both fluid and sodium are lost
Which IV solution can be used with blood products?
0.9% NS
LR (lactated ringer’s) tonicity
Isotonic
What does LR contain?
Sodium, potassium, chloride, calcium, and lactate
What does LR do?
Expands the ECF
LR is ideal for
Surgery, burns, and GI losses
When is LR contraindicated according to the lecture?
Liver problems, hyperkalemia, and severe hypovolemia
What is TPN?
Nutrition containing concentrated carbohydrates, fats, proteins, and electrolytes
When is TPN used?
When a patient has limited or no oral intake
Can TPN supplement enteral feedings?
Yes
What must happen to TPN before administration?
It requires refrigeration prior to administration
How long can a TPN bag be up before discarding?
24 hours
What should be done when starting a new TPN bag?
Hang a new line and new filter
Major TPN complications
Fluid/electrolyte imbalances, fat embolism, infection
What does IVPB stand for?
IV piggyback
What is IVPB used for?
Administering IV medications or fluids
Where should the primary bag be compared with the secondary IVPB bag?
The primary bag should be lower than the secondary bag
Before starting an IVPB, what clamp should you check?
Make sure the secondary clamp is open
If the nurse hangs the secondary bag below the primary bag
Something is wrong. The secondary bag needs to be higher than the primary bag.
PICC stands for
Peripherally inserted central catheter
Where is a PICC inserted?
A vein in the arm, with the catheter terminating centrally
How long might a PICC be used?
1 week to 6 months
Can you draw blood from the PICC arm?
The lecture says cannot use the arm for BP or blood draw
Can you perform venipuncture in the PICC arm?
Avoid it
Major PICC complications
DVT and phlebitis
Major advantage of a PICC
Lower infection rate, fewer insertion complications, decreased cost
Where does a centrally inserted catheter terminate?
Distal end of the superior vena cava
What can central venous access be used for?
IV fluids/medications, vesicants, blood products, PN, hemodynamic monitoring, blood samples, and contrast
Major disadvantage of central venous access
Increased risk of systemic infection
Central line infection signs/concern
Infection can occur from contamination or migration of organisms
Pneumothorax can occur because of
Perforation of the visceral pleura
Catheter migration can occur because of
Improper suturing
Catheter damage can occur because of
Trauma or forceful flushing
What should you do if a PICC has moved?
Stop using it
Why avoid BP in a PICC arm?
To avoid complications involving the catheter/vascular access
What syringe size should be used for central line flushing?
10 mL syringe or larger