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Pathogens
Disease causing microorganisms
Disease
Microorganisms overcome the body’s defenses
Pathology
Scientific study of disease
Etiology
cause
Pathogenesis
Development
Infection
Invasion and growth of pathogens in the body
Host
Organism that shelters and supports the growth of pathogens
Disease
State in which the body is not properly adjusted or is incapable of preforming normal functions
Normal microbiota
Microbes that live stably in and on the human body
Transient microbiota
microbes that are present for various periods and then disappear
Microbial antagonism
Normal microbiota prevent pathogens from causing an infection
Symbiosis
normal microbiota and host live together
Commensalism
one organism benefits and the other is unaffected
Mutualism
Both organisms benefits
Parasitism
One organism benefits and one is harmed
Opportunistic pathogens
Do not cause disease under normal conditions but cause disease under special conditions
Syndrome
A specific group of symptoms or signs that always accompanies a specific disease
Communicable diseases
Transmitted directly or indirectly from one host to another
Contagious disease
Very communicable disease that is capable of spreading easily and rapidly from one person to another
Noncommunicable disease
Caused by microorganisms that normally grow outside the human body and are not transmitted from one host to another
Incidence
Number of people contracting the disease
Prevalence
Number of people with the disease
Sporadic
Disease that occurs occasionally in a population
Endemic
Disease that is consistently present within a specific population or geographic area
Epidemic
Disease that affects a large number of individuals within a specific area over a short period of time
Pandemic
Epidemic that occurs worldwide
Actute
Disease in which symptoms develop rapidly but lasts for only a short time
Chronic
Disease that develop slowly and persist for long periods
Latent
Period of no symptoms when the pathogen is inactive
Herd immunity
The presence of immunity to a disease in most of the population
Primary infection
Acute infection that causes the initial illness
Secondary infection
Occur after the host is weakened from a primary infection
Subclinical / Inapparent
Infection does not cause any signs or symptoms of disease in the host
Incubation period
Interval between the initial infection and the first appearance of signs and symptom
Prodromal period
The appearance of the first mild signs and symptoms
Period of illness
The disease is at its height and all disease signs and symptoms are apparent
Period of decline
Signs and symptoms subside
Convalescence
Body returns to its pre diseased state and health is restored
Reservoir of infection
Continual source of infection
Zoonoses
Diseases that affect wild and domestic animals and can be transmitted to humans
Fomite
Nonliving objects that can spread infections
Vehicle transmission
Transmission by air, water, or food
Arthropod vectors
Carry pathogens from one host to another by mechanical and biological transmission
Microorganisms
Living things too small to be seen with the unaided eye
Genus
First name in organism
Specific Epithet
Second name of organism
Prokaryotic
unicellular with no nucleus
Prokaryotic examples
Bacteria and Archaea
Bacteria
has peptidoglycan cell wall
Archaea
cell wall lacks peptidoglycan and doesn’t cause disease in humans
Eukaryotes
Unicellular / multicellular and has nucleus
Eukoytes examples
Fungi, algae, Protozoa, humans
Fungi (mushrooms, mold, yeasts)
Contains chitin in cell wall and nucleus contains DNA
Algae
Obtain nourishment by photosynthesis
Protozoa
live as free entity or parasites that absorb organic compounds from environment
Acellular
not made of cells / not living
Acellular example
Virus
Virus
requires a host to reproduce and be considered living
Cell Theory
The concept that all living things are composed of cells
Spontaneous Generation
the idea that living organisms could arise from nonliving matter
Biogenesis
Living cells can arise only from preexisting cells
Pasteurization
Heating process used to kill bacteria in some alcoholic beverages and milk
Koch’s postulates
Procedures used to prove that a particular microorganism causes a particular disease
Synthetic Drugs
Chemically prepared in the laboratory
Antibiotics
Substances produced naturally by bacteria and fungi to inhibit the growth of other microorganisms
Mycology
study of fungi
Genomics
Study of an organisms genes
Bioremediation process
Use bacteria to clean up toxic wastes
Biotechnology
using microbes to make products such as food and chemicals
Biofilms
Bacterial communities that form slimy layers on surfaces
Infectious disease
When pathogens invade a susceptible host
Emerging infectious disease (EID)
New or changing disease showing an increase in incidence