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What does oxidative phosphorylation include?
The electron transport Chain and chemiosmosis
Where does oxidative phosphorylation occur?
In the inner mitochondrial membrane
What is the electron transport chain?
A series of steps for pumping protons into the inter membrane space to pass energy between complexes and create a concentration and chemical gradient
What oxidizes at complexes I and II?
I: oxidizes NADH into NAD+
II: oxidizes FADH2 into FAD
What does coenzyme-Q do?
Received energy from complex I to use at complex II
What does cutochrome-C do?
Transports a proton to complex IV
What does complex IV do?
It takes the remaining energy from passing electrons to synthesize water from O2
What does ATP synthase do for chemiosmosis?
It pulls protons back in and synthesizes ATP from ADP and Pi
Why does cyanide affect ATP production?
It binds to where O2 usually binds and blocks the process of reduction, preventing the creation of H2O and causing ATP synthase to shut down
What are the redox reactions in the ETC?
Electrons pass from one complex to another until they react with H+ and O2 to create H2O
How are redox reactions fueled and what do they create?
They use energy from electrons and create an electrochemical gradient
What happens without O2 in the ETC?
NADH and FADH2 can't be oxidized, which affects glycolysis
How does alcohol fermentation contribute to oxidative phosphorylation? And what is wrong with the process?
It regenerates NAD+ by reducing NADH into EtOH and NAD+ — ethanol is excreted and eventually accumulates to toxic levels
What is lactic acid fermentation?
the process of producing NAD+ from pyruvate without releasing CO2
How does lactic acid fermentation work?
pyruvate and NADH are reduced into lactate and NAD+
When does lactic acid fermentation occur?
in anaerobic conditions
How many ATP does lactic acid fermentation produce as opposed to aerobic respiration?
2 ATP instead of 32 ATP
What are the waste products of lactic acid fermentation?
alcohol, CO2, and lactic acid