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Epithelium (ectoderm) forms
the lamina (layer)
The tooth germ grows from the
lamina into the underlying tissue (mesoderm)
The dental papilla forms the
Dentin and pulp
The dental sac forms the
Cementum, PDL, and lamina dura
Lamina dura is
bundle bone that lies adjacent to the periodontal ligament, lining the tooth socket. The lamina dura surrounds the tooth socket and provides the attachment surface with which the Sharpey's fibers of the periodontal ligament perforate. On an x-ray a lamina dura will appear as a radiopaque line surrounding the tooth root
Basal Lamina
1. the layer of the basement membrane lying next to the basal surface of the adjoining cell layer, comprising two layers, the electron-lucent lamina lucida and the electron-dense lamina densa.
2. sometimes, the entire basement membrane.
Basement Membrane
(a thin sheet of fibers underlying the epithelium) separates the enamel from the dental papilla...which becomes the DEJ. REE (reduced enamel epithelium) protects the tooth until it erupts.
Hertwigs Root Sheath
An elongation of the cervical loop, which helps determine the shape, size, and number of roots and which influences the formation of dentin during the developmental stages of a tooth
The Rests of Malassez
Epithelial remnants of Hertwigs in the periodontal membrane; sometimes develops into a dental cyst
Stomodeum
Becomes the oral cavity and nasal cavity; results from invagination of the ectoderm at the cephalic end of the embryo
Buccopharynge al membrane
When the ectoderm meets the endoderm
Separates the primitive mouth from the foregut
When does the buccopharyngeal membrane rupture?
4th week in utero
Anterior lobe of hypophysis
The developing pituitary gland
When does the anterior lobe of hypophysis develop?
3rd week in utero
Rathke’s pouch
The pit that is formed by the formation of the anterior lobe of hypophysis
Frontal process
Large bulb in cephalic portion caused by fore brain
Frontal processes
Gives rise to the nasal septum, upper part of the face, and anterior part of the roof of the mouth
Arch I
Mandible and large part of maxilla
Arches II, III, IV
Join with I to make the tongue
Mesenchymal cells
Embyronic cells
2 Maxillary processes
Form the upper part of the cheeks, side of the upper lip and the palate
2 Mandibular processes
Lower part of the cheeks, lower lips, lower jaw, part of the tongue
Nasal septum
Results from an ingrowth of the medial nasal process into the stomodeum; divides the right and left nasal chambers
Globular Process
Develops from the medial nasal process; extends below the olfactory pits; lies between the right and left maxillary processes; forms the philtrum
Cleft lip
The partial or complete failure of the maxillary process to merge with the globular process; can be unilateral or bilateral
When is cleft lip apparent?
2nd month in utero
Mascrotomia
Failure of the sides of the mouth to close during embryonic development
When does the palate start to develop?
Near the end of the 2nd month in utero
Three growths in the stomodeum that form the palate
Right lateral palatine process, left lateral palatine process, premaxillary area
Palate
The fusion of the right and left maxillary process with premaxillary process forming a Y-shaped closure
When is fusion of the palate completed?
By the 12th week in utero
Cleft Palate
Failure of the fusion of the lateral palatine processes with each other or with the premaxillary process
When is cleft palate apparent?
By the 12th week or 3rd month in utero
3 anterior swellings that form the tongue
Tuberculum impar (middle); right lateral lingual swelling, left lateral lingual swelling
Posterior swelling that help form the tongue
Copula
When does the tongue begin to develop?
4th week in utero
Where does the body of the tongue develop from?
1st branchial arch
Where does the base of the tongue develop from?
2nd, 3rd, 4th branchial arches
When is the tongue recognizable
By the end of the 2nd month in utero
Thyroid gland
Originates from the foramen cecum, a depression posterior to the circumvallate papillae on the tongue
When is the thyroid gland apparent?
About 17 days in utero
Thyroglossal duct
Duct that thyroid gland uses to travel to the throat
What happens in the first (mandibular) branchial arch
Formation of bones, muscles, and nerves of the face
What happens in the second (hyoid) branchial arch?
Formation of the styloid process, stapes of the ears, stylohyoid ligament
What happens in the forth, fifth, and sixth branchial arches?
Formation of the structure of the lower throat, thyroid cartilage, muscles and nerves of the pharynx and larynx
Hard and soft palates
Formed from two separate embryonic structures; primary and secondary
In what week of prenatal development do the teeth develop?
When the embryo is 5-6 weeks old
Where does tooth development begin?
In the anterior mandibular region then in the anterior maxillary region
Embryology
Study of prenatal development in the stages before birth
Histology
Study of the structure and function of the tissues on a microscopic level
Earliest signs of tooth development
Found in the anterior mandibular region, when the embryo is 5 to 6 weeks old
At birth there are ____ in various stages of development
44 teeth
Life cycle of a tooth:
Growth
Calcification
Eruption
Bud stage
Formation of tooth begins
Cap stage
Cells of the developing tooth increase
Bell stage
Different tissues of the tooth form and its shape is established
Fissure
Fault along a developmental groove on the occlusal surface caused by incomplete or imperfect joining of the lobes during the formation of the tooth
Pit
Results when two developmental groove cross each other, forming a deep area that is too small for the bristle of a toothbrush to clean
Enamel
Hardest material of the tooth body
Pulp
Made up of nerves and blood vessels, and arteries of the body through a small opening at the tip of the root known as "Apical Foramen"
Alveolar crest
Is the highest point of the alveolar ridge
Which period of prenatal development is the most critical?
Embryonic period
Name the process for the laying down or adding of bone
Deposition
Name the process of bone loss or removal
Resorption
What is the first sign of tooth development?
Formation of the primary dental lamina
Dental lamina grows down into underlying ___________ in ___ maxillary and ____ mandibular spots
Mesenchyme, 10, 10
What are the spots of dental lamina that grow into the underlying mesenchyme?
tooth buds/germ
Small clumps of cells with the ability to form tooth tissues
Tooth buds/germ
How many embryonic tissues make up tooth germ? What are they?
2: ectoderm and ectomesenchyme
Tissue from the dental lamina;
Is from oral epithelium
Ectoderm forms;
Skin, lining of oral/nasal cavity, enamel, salivary glands, nerves
Ectomesenchyme
Tissue from neural crest cells; Underlies ectoderm; it is a specialized connective tissue
Parts of the tooth germ
Enamel organ, dental papilla, dental sac
Enamel organ
Forms enamel; from ectoderm
Dental papilla
Forms dentin + pulp; from mesenchyme
Dental sac
Forms cementum, PDL, lamina dura; from mesenchyme
Stages of enamel organ development; morphodifferentiation
Bud stage (1st)
Cap stage (2nd)
Bell stage (3rd)
Bud Stage includes the formation of the tooth ____, ________ _______develops, appearance of ____________, then a budding off from the dental lamina.
Bud, enamel organ, mesenchyme
Stage of enamel organ development in which the dental papilla if formed, enamel organ has 2 layers, and the vestibular lamina appears
Cap stage (2nd)
Stage of enamel organ development which includes formation of hard tissues, four layered enamel organ, form of crown is determined, and the bud of the permanent tooth forms; there is also morpho- and cytodifferentiation
Bell stage (3rd)
Four layers of the Enamel Organ
OuterStellate Reticulum (SR)
Enamel Epithelium (OEE)
Stratum Intermedium (SI)
Inner Enamel Epithelium (IEE)
What layer of the enamel organ has cuboidal cells, protective function, direct connection with basal layer of epithelium, and organizes a network of capillaries that will bring nutrition to the ameloblasts?
Enamal Epithelium (OEE)
What layer of the enamel organ consists of a loose network of epithelial cells resembling connective tissue cells, makes up the bulk of the enamel organ, transmits nutrients to SI,and acts as a cushion for the IEE?
stellate reticulum
What layer of the enamel organ is made up of packed, flattened epithelial cells and helps provide nourishment for the IEE?
stratum intermedium
What layer of the enamel organ has a single layer of columnar epithelial cells, is next to the dental papilla separated by a basement membrane (future DEJ), and is continuous with the OEE? What layer of cells will become ameloblasts and is responsible for actual enamel formation?
Inner enamel Epithelium (IEE)
Future area of the CEJ
An area where the OEE and IEE meet at the most apical edge
cervical loop
The end of the cervical loop is where the _______ begins
root sheath (HERS)
T/F Enamel forms before dentin
FALSE;Dentin forms before enamel
Tooth formation starts at the _______ and _______ as well as along the ____.
incisal edge and cusp tips, DEJ
______ forms first then tooth formation progresses ________ to form the ____.
Crown;downward, root
Stages of Eruption
1: pre-eruptive
2: pre-functional (active) or passive eruptive
3: post-eruptive/functional (active)
stage of eruption that begins when the crown is formed; from developmental position and root formation to functional occlusion
pre-functional (active)
stage of eruption that exhibits occlusal wear and attrition; added cementum at apex of root
post-eruptive/functional (active)
stage of eruption that looks like the tooth erupts, but in reality the gingiva recedes instead
passive eruption
Causes for Exfoliation/Eruption
1: increase in permanent tooth size
2: attached PDL fibers are lost
3: increased masticatory forces or muscle growth
4: facial growth of arches and alveolar processes
What happens with premature loss of a deciduous tooth?
normal jaw growth may not take place: 1 side develops differently
Why does one side of the jaw develop differently when a primary tooth is prematurely lost?
chewing only on 1 side; chewing side stimulates bone growth only on that side
Problems with mixed dentition
retained root tips;
permanent tooth impactions,
midline diastimas,
submerged/impacted primary teeth
ectopic eruption
Retained root tips most commonly occur in primary ______. What teeth replace them?
molars;premolars
The inner part of the JE is attached to the tooth via the ______ lamina by _________.
basal;hemidesmosomes