(RMT) Chem - Quality Control

controlla

quality assurance

process of laboratory ensures quality results by closely monitoring preanalytical, analytical, and post-analytical stages of testing

quality control

part of analytical phase

quality control

process of monitoring results from control samples to verify accuracy

mean

average

median

midpoint of distribution

mode

most frequent observation

range

difference between highest and lowest value

range

easiest measure of spread

standard deviation (SD)

most frequently used measure of variation

coefficient of variation

index of precision

coefficient of variation

used to compare the dispersion of two or more groups of data wiith different units/concentration

T-test

..between means of two groups of data

F-test

..between the SD of two groups of data

bell curve

which symmetrical shape

68

fall between ±1 SD from the mean

95

fall between ±2 SD from the mean

99

fall between ±3 SD from the mean

accuracy

true value

precision

values to each other

reliability

to maintain accuracy and precision over an extended period

practicability

degree by which a method can easily be repeated

analytical sensitivity

ability to measure the smallest concentration of the analyte of interest

analytical specific

ability to measure only the analyte of interest

reportable range

aka linearity

reportable range

range of values over which laboratory can verify accuracy of test system

reference interval

fka normal value

establishing a reference interval

120-700 individuals

transference and validation of a reference interval

most common reference interval studies

transference and validation of a reference interval

40 study individuals

diagnostic sensitivity

% of population with the disease that tests positive

diagnostic specificity

% of population with the disease that tests negative

between 5 and 20 days

control materials should be analyzed