transcription/translation

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9 Terms

1
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Transcription initiation

RNA poly. binds to sigma which binds to the promoter causing DNA to unwind; NTPs present

2
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Transcription elongation

RNA poly. reads template strand and builds complementary base strand

3
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Transcription termination

RNA poly. reaches termination sequence and releases completed mRNA strand

4
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Transcription initiation (eukaryotic)

TATA binding proteins recognize and bind to the TATA box (upstream of the transcription site) and help position DNA poly.

5
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Translation initiation

SRS binds to mRNA at the start codon (AUG). tRNA carrying methionine pairs with the start codon and LRS joins to complete ribosome. 

6
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Translation elongation

Ribosome reads codons along the RNA and they are matched with complementary tRNA seq. with specific amino acids. Ribosome catalyzes peptide bond formation, creating polypep. chain

7
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Translation initiation (prokaryotic)

SRS binds to Shine-Dalgarno sequence to align the start codon. tRNA containing fMet pairs with the start codon

8
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Stop codons

UAA, UAG, UGA

9
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Translation initiation (eukaryotic)

SRS starts at 5’ cap and scans until AUG is found. Met binds to it.