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Cell
The smallest unit of structure and function in living systems
Robert Hooke
The first scientist to observe and name cells (1665)
Anton van Leeuwenhoek
The first scientist to use a simple microscope to observe bacteria and Protozoa (1676)
Cell Theory (Point 1)
All living things are made of cells
Cell Theory (Point 2)
Cells are the basic units of structure and function in living things
Cell Theory (Point 3)
New cells are produced from existing cells
Cytoplasm
Gel-like substance that houses cellular structures/organelles
Cell Membrane (Plasma Membrane)
A semi-permeable membrane that protects the cell, it allows certain substances in and out of the cell,
Ribosomes
RNA enzymes that assemble proteins, NOT a membrane bound organelle,
Genetic Material
DNA, which directs cell activity and is used for reproduction,
Prokaryotic Cells
Lack a Nucleus and Membrane Bound Organelles (MBOs), DNA is in a region called the nucleoid, generally smaller and simpler
Eukaryotic Cells
Have a true nucleus and membrane bound organelles, generally larger and much more complex
Endosymbiotic Theory
Theory to determine how eukaryotic organisms arose, suggests a large ancient prokaryote engulfed a smaller prokaryote and lived in a symbiotic relationship
Endosymbiotic Theory Evidence
Mitochondria and Chloroplasts both have inner and outer membranes, possess their own DNA and Ribosomes, and divide independently of the cell, similar to bacteria
Unicellular Organism
Composed of a single cell, generally reproduce quickly and efficiently
Multicellular Organism
Composed of millions/trillions of cells, have many specialized cells that perform specific functions
Colonial Organism
Composed of physically connected interdependent individuals that can function alone or as a unit, examples include Slime molds, Volvox, and Bees
Homeostasis
The state of steady internal, physical, and chemical conditions maintained by living systems, a balance maintained through self-regulating adjustments,
Positive Feedback Mechanism
Amplifies or increases changes to a system, input causes an increase in output, which triggers a further increase in input (Examples: Pepsin production, Oxytocin in labor, Ethylene in fruit ripening),
Negative Feedback Mechanism
Dampens or decreases ("turn off") changes to a system, input causes an increase in output, which triggers a decrease in input (Examples: Thermoregulation, pH regulation, Photoregulation),
Fluid-Mosaic Model
Describes the cell membrane as a 2-DIMENSIONAL LIQUID that is constantly shifting,,
Phospholipid Bilayer
Forms the bilayer structure of the cell membrane, acting as a selective barrier, with hydrophilic heads facing outward and hydrophobic tails inward
Cholesterol
Helps maintain the fluidity and stability of the cell membrane by preventing the fatty acid chains of the phospholipids from sticking together, especially in temperature changes
Integral Protein (Intrinsic Protein)
Embedded across the membrane, involved in transporting molecules in and out of the cell or acting as receptors for signaling,
Peripheral Protein (Extrinsic Protein)
Located on the surface of the membrane, assist in cell structure by interacting with the cytoskeleton or participate in cell signaling,
Glycolipid
Involved in cell recognition and communication by interacting with molecules outside the cell, playing a key role in immune response and tissue formation,
Glycoprotein
Involved in cell signaling and recognition, where the carbohydrate portion interacts with other cells and molecules, especially in immune response,
Carbohydrate Chain/Branch
Attached to lipids or proteins, acts as markers for cell-to-cell communication and help in the identification of the cell by other cells,
Nucleus
The control center of the cell, contains nearly all of the cell’s DNA
Nuclear Membrane (Envelope)
A double membrane that is dotted with thousands of pores, allowing materials to move into and out of the nucleus
Nucleolus
Manufactures ribosomes
Endoplasmic Reticulum (ER)
An extensive internal membrane system that accounts for more than half the total membrane in a cell
Rough E.R.
Has ribosomes attached, involved in the synthesis and movement of proteins,
Smooth E.R.
Has no ribosomes attached, function is to synthesize lipids
Golgi Apparatus
Appears as a stack of loosely connected membranes, function is to modify, sort, package, and ship substances that have arrived from the endoplasmic reticulum
Lysosomes
Contain hydrolytic enzymes, function in the digestion of carbohydrates, proteins, and lipids, recycling organic materials, and destroying old organelles, plant cells do not have lysosomes,
Mitochondria
The “Powerhouse” of the cell, purpose is cellular respiration, converting glucose or sugar molecules into a usable form of energy (ATP)
Cristae
Folds on the inner membrane of the mitochondria, they increase the surface area for respiration
Vesicles
A storage area inside a cell for water, salts, proteins, and carbohydrates
Dynein
A motor protein that moves vesicles along microtubules
Peroxisome
A modified vesicle that gets rid of free radicals in the body, they produce hydrogen peroxide and contain catalase to break it down
Cytoskeleton
Internal framework and support system found in plant and animal cells, maintains shape, facilitates cell movement, and aids in intracellular transport
Microtubules
Rigid cytoskeletal structures made of Tubulin protein, function in intracellular transport, cell movement, and cell division,
Microfilaments
Flexible cytoskeletal structures made of Actin protein, function to maintain shape and provide cellular support (scaffolding beneath cell membrane)
Intermediate Filaments
Cytoskeletal structures made of Actin and other fibrous subunits, they provide mechanical strength to hold cells together at junctions and hold organelles in place
Centrioles
Organize the cytoskeleton and help separate chromosomes during cell division
Endomembrane System
The internal membrane system of a cell (including RER, SER, Vesicles, Lysosomes, Peroxisomes, Transport Vesicles, Golgi) that transports proteins and other nutrients throughout the cell
Chloroplasts
The organelle where photosynthesis takes place, converting sun energy into chemical energy (glucose), contains thylakoids
Thylakoids
Large stacks of membranes inside the chloroplasts that contain the green pigment chlorophyll
Large Central Vacuole
A very large vacuole found in mature plant cells, creates Turgor Pressure when filled with water, providing strength and support, and stores organic compounds
Turgor Pressure
Pressure created when the large central vacuole is filled with water, giving strength and support to the cell
Cell Wall
A supporting structure found in cells of plants, fungi, and bacteria, provides support and protection, composed of cellulose and lignin in plants.
Cell Transport
The movement of materials across cell membranes
Passive Transport
DOES NOT require ATP and moves substances from an area of HIGH concentration to LOW concentration
Simple Diffusion
The passive transport of typically small, hydrophobic, or gaseous substances without the aid of membrane proteins,
Facilitated Diffusion
The passive movement of substances (like biological molecules or ions) across a plasma membrane by means of a transport protein,
Osmosis
The movement of water molecules from a solution with a high concentration of water molecules to a solution with a lower concentration of water molecules, through a partially permeable membrane
Aquaporins
Channels involved in osmosis
Hypertonic Solution
A solution that has a HIGHER solute concentration than the cell
Hypotonic Solution
A solution that has a LOWER solute concentration than the cell
Isotonic Solution
A solution that has an EQUAL solute concentration to the cell
Lysed (Animal Cell)
The result when an animal cell swells/bursts in a hypotonic solution
Turgid (Plant Cell)
The normal, firm state of a plant cell when water enters by osmosis and pushes against the cell wall,
Shriveled (Animal Cell)
The result when an animal cell loses water to a hypertonic solution
Plasmolyzed (Plant Cell)
The result when a plant cell loses water, causing the vacuole to shrink and the cell to lose shape in a hypertonic solution,
Active Transport
Requires ATP and moves substances from an area of LOW concentration to HIGH concentration
Protein Pumps
Proteins capable of pumping compounds in and out of the cell,
Symport
Substances being moved in the same direction via a protein pump
Antiport
Substances being moved in a different direction via a protein pump
Uniport
Substances moving in only one direction via a protein pump
Sodium-Potassium Pump
Crucial pump in nerve cells for sending electrical signals throughout the body
Endocytosis
The process by which cells take in substances from outside of the cell by engulfing them in a vesicle,
Phagocytosis
Cell "eating" large particles
Pinocytosis
Cell "drinking" fluids
Receptor-Mediated Endocytosis
A process through which bulk amounts of specific molecules can be imported into a cell after binding to cell surface receptors
Exocytosis
The process by which cells move materials from within the cell into the extracellular fluid,
Ligand
A small signal molecule (e.g., Neurotransmitter, Hormone) that binds to receptors to transmit signals within or between cells
Receptor
Proteins that bind to ligands that initiate signal transduction
Signal Transduction
The transmission of a signal along a communication pathway
includes all cellular processes that come after ligand binding,
Response
The final cellular action in a signaling pathway, such as lowered blood sugar in the Insulin pathway
Tight Junction
Seals neighboring cells together and prevents leakage (Common in Stomach Lining)
Gap Junction
Allows passage of small water-soluble ions (Common in Cardiac Muscle, Nerves)
Desmosome
Joins intermediate filaments in one cell to those of a neighboring cell (Common in Skin, Muscle),
Hemidesmosome
Anchors intermediate filaments in a cell to the base (Common in Skin)
Plasmodesmata
Membranous channels that cross walls of adjacent plant cells, linking the cytoplasm, plasma membranes and ER, allowing cell-to-cell communication
Cell Size Limitation Solution (Divide)
A way cells cope with a decreasing surface area to volume ratio (SA:Vol)
Cell Size Limitation Solution (Metabolism)
Cells slow metabolism to lower energy needs and produce less waste
Cell Size Limitation Solution (Change Shape)
Cells change shape (e.g., become thin/flat or develop many folds in the cell membrane) to increase surface area