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Anticoagulants

Medications used to prevent the coagulation of blood.

Clotting pathway

A series of steps involving various factors that lead to the formation of a blood clot.

Prothrombin

A protein in the blood that is converted to thrombin during the coagulation process.

Thrombin

An enzyme that converts fibrinogen into fibrin, a key step in the blood clotting process.

Venous thromboembolism (VTE)

A condition that includes both deep vein thrombosis (DVT) and pulmonary embolism (PE).

Atrial fibrillation

A heart condition characterized by an irregular and rapid heartbeat.

INR

International Normalized Ratio; a standardized measure of blood clotting.

Activated partial thromboplastin time (aPTT)

A blood test that measures the time it takes for blood to clot.

Heparin-induced thrombocytopenia (HIT)

A serious immune reaction to heparin that results in low platelet counts.

Thrombocytopenia

A condition characterized by an abnormally low number of platelets in the blood, increasing the risk of bleeding.

Warfarin

An anticoagulant medication that inhibits vitamin K and is used to prevent blood clots.

Dabigatran (Pradaxa)

A direct thrombin inhibitor used to prevent blood clots.

Rivaroxaban (Xarelto)

A direct factor Xa inhibitor used to reduce the risk of blood clots.

Acetylsalicylic Acid (ASA)

Commonly known as aspirin, it is used to prevent platelet aggregation.

Clopidogrel (Plavix)

An antiplatelet medication that inhibits ADP receptors.

Plasmin

An enzyme that breaks down fibrin in blood clots during the process of fibrinolysis.

Fibrinolysis

The process of breaking down fibrin in blood clots.

Vitamin K

A vitamin necessary for the synthesis of certain clotting factors.

Prostaglandins

Compounds that perform various functions including promoting inflammation.

Thromboxane A2

A compound that promotes platelet aggregation and vasoconstriction.

Fibrinogen

A blood plasma protein that is converted into fibrin during clot formation.

Polycythemia

An increase in the number of red blood cells, which can increase blood viscosity and clotting risk.

Deep Venous Thrombosis (DVT)

A condition where blood clots form in the deep veins, usually in the legs.

Pulmonary Embolism (PE)

A blockage in a pulmonary artery, often due to blood clots traveling from the legs.

Acute Coronary Syndromes (ACS)

A range of conditions associated with sudden reduced blood flow to the heart.

Bleeding precautions

Measures taken to prevent excessive bleeding in patients on anticoagulant therapy.

Fibrin clots

Clots formed by fibrin, which is a result of the coagulation cascade.

Antidote

A substance that counteracts the effects of a poison or overdose.

Patient teaching

Educating patients on managing their condition and medications.

Activated Factor X (Xa)

An enzyme that plays a key role in the coagulation cascade, converting prothrombin to thrombin.

Recombinant Factor VIIa

A medication used to promote blood coagulation in patients with bleeding disorders.

Hemophilia

A genetic disorder that impairs the body's ability to make blood clots.

Antithrombin III

A protein in the blood that inhibits clotting, particularly that of thrombin and factor Xa.

Vitamin K deficiency

A condition where the body lacks sufficient vitamin K to support normal blood clotting.

Thromboembolism

The obstruction of a blood vessel by a clot that has migrated from another site in the vascular system.

Hemostasis

The process of blood clot formation to stop bleeding.

Thromboxane

A lipid compound that promotes platelet aggregation and vasoconstriction.

Antiplatelet therapy

Treatment aimed at preventing platelets from clumping together to form clots.

Thrombophilia

A disorder in which the blood has an increased tendency to form clots.

Acquired thrombophilia

A condition that develops due to other factors, such as certain medical conditions or medications.

Inherited thrombophilia

A genetic disorder that predisposes individuals to thrombus formation.

Fibrin sealant

A surgical product made from fibrin that acts as a hemostatic agent.

Bleeding disorders

Conditions that cause abnormal bleeding due to issues with blood clotting factors.

Stasis

A condition where blood flow is slow or stagnant, which can lead to clot formation.

Compression stockings

Garments designed to improve circulation and prevent blood clots in the legs.

Procoagulant

A substance that promotes blood coagulation.

Anticoagulant reversal

Administering a treatment to counteract the effects of anticoagulant medications.

Cardiovascular disease

A group of disorders affecting the heart and blood vessels, often linked to clotting issues.

Periprocedural anticoagulation

Management of anticoagulation therapy in relation to surgical or invasive procedures.

Thrombotic events

Occurrences of thrombosis, which can lead to conditions like heart attack or stroke.

Pneumatic compression devices

Devices used to enhance venous circulation and prevent blood clots in hospitalized patients.

Anticoagulation monitoring

The process of regularly checking the effectiveness and safety of anticoagulant therapy.

Factor deficiencies

Conditions caused by the lack of specific blood clotting factors needed for hemostasis.

Post-thrombotic syndrome

A condition that can occur after DVT, leading to chronic pain and swelling in the affected leg.

Compression therapy

A treatment approach aimed at increasing venous blood flow to prevent clot formation.