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moral model of addiction
views addiction as a result of personal moral failure or weakness, focusing on blame and responsibility
brain disease model of addiction
frames addiction as a chronic brain disorder involving neurobiological changes that impair control and decision-making
developmental learning model of addiction
emphasizes how learning, environment and development shape addictive behaviors over time, combining neurobiology with psychological and social factors.
Holton and Berridge’s model of addiction
Proposes that addiction involves strong, cue-triggered “incentive salience” (wanting) that can override reflective self-control.
Electroencephalography (EEG)
Measures electrical activity in the brain using electrodes on the scalp, good for tracking timing of brain events.
Positron emission tomography (PET)
Uses radioactive tracers to image brain metabolism or neurotransmitter activity.
Functional magnetic resonance imaging (fMRI)
Uses magnetic fields to detect brain activity by tracking blood flow changes.
Blood oxygen level dependent (BOLD) fMRI
A type of fMRI signal that reflects changes in blood oxygenation related to neural activity.
Voxel
A 3D pixel in brain imaging, representing a small volume of brain tissue.
Level of significance
The threshold (often p < 0.05) below which a result is considered statistically significant.
forward inference
Drawing conclusions about which brain regions are active during a known cognitive process.
cognitive subtraction
Comparing brain activity between two tasks to isolate a specific process.
reverse inference
inferring a cognitive process from observed brain activity (often criticized as weak)
problem of multiple comparisons
increased chance of false positives when many statistical tests are run
non-independence error
mistake of using the same data to select and test regions inflating false positives
test-retest reliability
the consistency of a measurement across repeated sessions
Comparing brain activity between two tasks to isolate a specific process.
Using brain data to infer thoughts, feelings, or intentions.
Psychological states vs. psychological traits
States are temporary (e.g., anger now); traits are enduring patterns (e.g., being an angry person).
Comparison question test
A polygraph method comparing responses to relevant and control questions.
Guilty knowledge test
Detects recognition of crime details only the guilty would know.
false positive
incorrectly identifying a condition when it’s not present
false negative
failing to detect a condition when it is present
ethical concerns about brain reading
issues of privacy, consent, accuracy, and misuse of inferred mental content
neuroprediction (criminal and medical contexts)
Using brain data to predict future behavior or health outcomes.
Area under the ROC curve (AUC)
A measure of predictive accuracy (ranges 0–1; higher is better).
Simpson’s paradox
When a trend appears in separate groups but reverses when combined.
Ethical concerns (violent behavior, recidivism)
Risks of discrimination, false labeling, and undermining justice.
Ethical concerns (neurodegenerative diseases
Issues of autonomy, stigma, and psychological harm from predictive information.
descriptive enhancement
any improvement beyond normal
normative enhancement
whether such improvement is good or desirable
pharmacological cognitive enhancement
using drugs to improve mental abilities in healthy people
Methylphenidate (Ritalin), Amphetamine (Adderall)
Stimulants that increase dopamine and norepinephrine levels, boosting attention and alertness.
Ethical concerns (cognitive enhancement)
Debates over safety, fairness, coercion, authenticity, identity, and human flourishing.
short term memory
limited capacity; temporary
long term memory
durable, large capacity
declarative memory
conscious facts/events
nondeclarative memory
unconscious skills/habits
Procedural memory, learned defensive responses, learned affective feelings
Types of nondeclarative memory (skills, automatic reactions, emotional patterns).
episodic memory
personal events
semantic memory
general knowledge
memory blunting (and erasing)
reducing or removing emotional intensity or memory content
consolidation
stabilizing new memories
reconsolidation
modifying memories upon recall
propanolol
a beta-blocker that can weaken emotional memory reconsolidation by blocking noradrenergic activity
ethical concerns (memory blunting)
worries about authenticity,
“Dearth” thought experiment (status quo preference)
A challenge to the idea that we should prefer the current human condition just because it’s familiar.
Brain-computer interfaces (BCIs)
Systems that link brain activity directly to external devices for communication, control, or feedback.
Closed-loop BCI
A BCI that adjusts in real time based on feedback from the user or environment.
Ethical concerns (BCI enhancement)
Issues of fairness, autonomy, identity, and unintended consequences.
Ethical concerns (BCI treatment)
Risks in clinical use, including safety, consent, and long-term effects.
Engineering model of medicine
Focuses on fixing or replacing malfunctioning biological systems.
Rehabilitation model of medicine
Focuses on restoring function and quality of life, often through therapy and support.
death
Irreversible cessation of biological functioning.
brain death
complete, irreversible loss of all brain function, included brain stem
coma
deep unconscious no wakefulness or awareness
vegetative state
wakefulness without awareness; eyes open, but no conscious response
Minimally conscious state (MCS)
Severely impaired consciousness with minimal but definite signs of awareness.
wakefulness
being physiologically awake
awareness
having conscious experience
neuroscientific evidence for awareness in VS
Brain imaging suggests some patients can show hidden signs of conscious processing.
psychological accounts of personal identity
continuity of memories/personalityb
biological accounts of personal identity
continuity of the living body/brain a
accounts of morally relevant interests/well-being
Hedonistic (pleasure), desire-satisfaction (getting what you want), objective list (certain goods inherently valuable).
Problem of other minds
How can we know others have minds like ours?
Physicalism about the mind
The view that mental states are entirely physical.
type identity
mental states are identical to specific physical kinds
token identity
each particular instance is identical to some physical event
contingent truths
true but could have been otherwise
necessary
true in all possible worlds