lithium - dr joshi

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11 Terms

1
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which of the following are the MOAs of lithium? (SATA)

a. inhibit DA release

b. inhibit GABA

c. inhibit 5HT

d. inhibit inositol monophosphatase

a. d.

2
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which of the following ions can be replaced by the lithium?

a. Ca

b. Mg

c. Na

d. Fe

c.

3
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in which of the following conditions is lithium contraindicated? (SATA)

a. hepatic disease

b. pregnancy

c. sick sinus

d. renal disease

b. c. d.

4
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which of the following are the common side effects of lithium? (SATA)

a. N/V/D

b. CNS

c. hepatic

d. pulmonary

a. b.

5
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which of the following is the major excretory pathway for lithium?

a. hepatic metabolism

b. renal excretion in unchanged form

c. hydroxylation

d. bile excretion

b.

6
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T/F lithium may replace Na ion in the body and distribute equally

TRUE

7
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which of the following is an adverse effect of lithium?

a. diabetes insipidus

b. diabetes mellitus

c. hepatitis

d. pulmonary inflammation

a.

8
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which of the following is true for lithium in pregnancy?

a. pregnancy A

b. pregnancy B

c. pregnancy C

d. pregnancy D

d.

9
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how may thiazide or loop diuretics affect lithium plasma concentration?

a. decr. tubular reabsorption

b. decr. tubular excretion

c. incr. tubular reabsorption

d. incr. tubular excretion

c.

10
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T/F lithium requires therapeutic drug monitoring

TRUE

11
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which of the following is a best alternative drug for BD in pregnancy?

a. valproic acid

b. carbamazepine

c. lurasidone

d. olanzapine

c.