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natural selection
traits that better enable living things to survive and reproduce are more likely to be passed down, “survival of the fittest”
eugenics
selective breeding to promote traits
epigenetics
environments can turn on or off genetic expression without dna change
neuron
nerve cell, basic building block of our nervous system
glial cells
they support the functioning of neurons:
transport nutrients to neurons
provide myelin insulation to neurons
help neurons line up closely with each other for neural communication
clean up waste
soma (cell body)
contains nucleus and serves as neuron’s life support center
dendrites
recieve signals from other cells, signals are transmitted across soma and down axon
axon
transmitting electrical impulses throughout nervous system
axon terminal buttons
small sacs that contain neurotransmitters that help pass on signal to neareby neurons
myelin sheath
coats axon and acts as insulator, increasing speed at which the signal travels
multiple sclerosis
dimished muscle control and impaired cognition due to deterioration of sheath
action potential (step 1 in neural firing)
brief electrical pulse that travels down neuron (dendrites to terminal buttons)
neurotransmitters (step 2 in neural firing)
chemicals (neurotransmitters) are released into synapse, potentially stiumlating nearby neuron to fire action potential
action potential definition
brief electrical charge that travels down its axon
resting potential
(-70mv) stable positive outside/negative inside state where positive ions are outside the axon, and negative inside
depolarization
first step in neuron firing; positive sodium ions flood into the cell making more positive toward action potential threshold
threshold of excitation
neuron has to reach a certain “threshold of excitation” in order for an action potential to be triggered (-55mv)
excitatory neurotransmitters
increase likelihood that neuron fill fire
inhibitory neurotransmitters
decrease likelihood that neuron will fire
failed initations
instances where some excitatory signals were recieved and cell depolarized a little bit, but wasn’t enough to trigger action potential
refractory period
brief period where neuron is not able to fire again
reuptake
when neurotransmitters get reabsorbed by axon terminal
acetylcholine
neurotransmitter that enables muscle action
malfunctions of acetylcholine
with alzhiemers disease, ach producing neurons deteroriate
if ach transmittion blocked, muslces cannot contract (myasthenia gravis)
dopamine
neurotransmitter that influences reward system
malfunctions of dopamine
overuspply = schizophrenia, undersupply = mobility in parkinsons disease
serotonin
neurotransmitter that effects mood, hunger, sleep
malfunctions of serotonin
undersupply = depression
norepinephrine
helps control alertness
malfunctions of norepinephrine
undersupply can depress mood
gaba
major inhibatory neurotransmitter
malfunctions of gaba
undersupply leads to seizures, tremors, and insomnia
glutamate
involved in memory, major excitatory neurotransmitter
malfunctions of glutamate
oversupply can overestimate the brain, producing migraines or seizures
endorphins
neurotransmitters that influence perception of pain or pleasure
malfunctions of endorphins
oversupply with opoid drugs can surpress the body’s natural endorphin supply
substance p
involved in pain perception and immune response
malfunctions of substance p
oversupply can lead to chronic pain
central nervous system (cns)
info sent to brain and spinal cord to be processed and acted on
peripheral nervous system (pns)
parts of nervous system that are not housed in bone; sensory and motor neurons that connect cns to body
sensory neurons
carries messages from body’s tissues and sensory receptors inward to brain and spinal cord for processing
motor neurons
carries instructions from cns outward to the body’s muscles and glands
interneurons
(in central nervous system), neurons that process information between sensory input and motor output
long term potentiation
increased efficiency in neural firing which can result from repeated connections between neurons
spinal cord
neural fibers in spinal cord serve as 2 way information highway; brain communicates with rest of body through pns
reflex
simple automatic response to sensory stimulus
reflex arc
composed of single sensory neuron and a single motor neuron, often communicate through interneuron in spinal cord
somatic nervous system
carries messages from senses to the cns and from cns to muscles
enables voluntary control of skeletal muscles
autonomic nervous system
controls internal organ muscles and glandular activity
controls activities that are normally outside of conscious control (ex: heartbeat)
what are the two subdivisions of the autonomic nervous system
sympathetic and parasympathetic
sympathetic system
(fight or flight) arouses body and mobilizes energy in the face of stress
parasympathetic system
calms body, conserving energy
endocrine system
body’s “slow” chemical communication system; set of glands + fat tissue that secrete hormones into bloodstream
hormones
chemical messengers produced by endocrine glands in body that travel bloodstream to target tissues and organs
adrenaline
hormone involved in fight or flight, beneficial in short bursts
oxytocin
hormone enables orgasm and lactation; promotes social bonding
leptin
hormone involved in turning off hunger (lean)
ghrelin
hormone involved in turning on hunger
melatonin
hormone helps turn on sleeping process
pituary gland
directs other endocrine glands to release hormones, controlled. by hypothalamus
agonists
chemicals that increase a neurotransmitter’s action, may increase production/release of them
antagonists
chemicals that decrease a neurotransmitter’s action by blocking production or release
reuptake inhibitors
blocks reuptake of neurotransmitter, leaves it in the synapse for longer which increases its effects
selective serotonin reuptake inhibitors
prevent reuptake of serotonin, treats depression, gives it more time to interact with serotonin receptors
substance use disorder
disorder characterized by continued substance use despite resulting life disruption
symptoms of substance use disorder
craving
continued use despite significant life disruption
tolerance
withdrawal
tolerance
needing more for desired effect
withdrawal
symptoms when one tries to cut back use of substance
categories of psychoactive drugs
depressants
stimulants
hallucinogens
depressants
drugs that calm neural activity and slow body functions
stimulants
excite neural activity and speed up body functions
hallucinogens
drugs that distort perceptions
opioids
used for pain and anxiety relief, users pupils constrict, breathing slows
alcohol
depressant
pros: initial high followed by relaxation and disinhibition
cons: depression, memory loss, organ damage, impaired reactions
heroin
depressant
pros: rush of euphoria, relief from pain
depressed physiology, loss of natural endorphin function
caffeine
stimulant
pros: increased alertness/wakefulness
cons: anxiety, restlelessness, insomnia in high doses
nicotine
stimulant
pros: arousal, relaxation, sense of well being
cons: heart disease, cancer
cocaine
stiumlant
pros: rush of euphoria, confidence, energy
cons: cardiovascular stress, suspiciousness, depressive crash
marijuana
mild hallucinogen
pros: enhanced sensation, relief of pain, distortion of time, relaxation
cons: impaired learning and memory, increased risk of psychological disorders