Hem Lab midterm

What is G6PD deficiency

Degmacytes, polychromasia, Heinz bodies, normocytic, normochromic

What is iron deficiency anemia (IDA)

Microcytic, hypochromic, low ferritin, high transferrin, high TIBC, low transferrin saturation %, high thrombocytosis

What is anemia of chronic disease

Microcytic, hypochromic, high ferritin, low transferrin, low TIBC, low transferrin saturation %, common in lupus, renal disease

What is sideroblastic anemia

Microcytic, hypochromic, iron satellites , pappenheimer bodies, basophilic stippling, acquired:lead poisoning, high ferritin , low transferrin, low TIBC, high transferrin saturation %

What is Megaloblastic anemia

Hypersegmented neutophils, ovalocytes, Macrocytic, high/normal iron. Ferritin, transferrin saturation %, elevated homocysteine, could have poikilocytosis +anisocytosis, pancytopenia observed, b12= elevated MMA

What is hemoglobin S

Increase retics, polychromasia, nRBCs, sickle cells, target cells (poikilocytosis) normal MCV, increase RDW, increase WBC, platelets, decrease RBC, Hj bodies, basophilic stippling, schistocytes, pappenheimer bodies

What is hemoglobin C

Pretty crystals (geometric), normal MCV, increase MCHC, increase retics, target cells, nRBCs

What is hemoglobin SC

Ugly crystals, target cells, nRBC, some sickle cells will be present

What is Beta thalassemia

Microcytic, hypochromic, target cells, nRBC, basophilic stippling, poikilocytosis, decrease retics, increase ferritin, decrease transferrin, minor= normal RDW

What is alpha thalassemia

Microcytic, hypochromic, poikilocytosis, target cells, nRBCs, increase ferritin, decrease transferrin, minor= normal RDW

What is hereditary spherocytosis

Sperocytes predominate, increase retics, mutation in vertical protein, increase osmotic fragility

What is hereditary elliptocytosis

Elliptocytes predominate, no poikilocytosis, increased thermal fragility

What is hereditary stomatocytois

>50% stomatocytosis

What is MAHA (microangiopathic hemolytic anemia )

Thrombocytopenia, schistocytes, nRBC, intravascular, anisocytosis, polychromasia,