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Melatonin
Gland: Pineal
Target: Thalamus
Function: Makes you drowsy
TSH Thyroid Stimulating Hormone
Gland: APG
Target: Thyroid
-Releases thyroxin
-HYPOsecretion: decreased thyroxin levels
-HYPERsecretion: over production of thyroxin and calcitonin
ACTH Adrenocorticotropic Hormone
Gland: APG
Target: Adrenal cortex
-Releases stress response hormones
-HYPOsecretion: inability to deal with stress
-HYPERsecretion: increase in blood glucose levels
hG Human Growth Hormone
Gland: APG
Target: Most body cells
-Body growth and daily repair at organs and tissues
-HYPOsecretion: dwarfism
-HYPERsecretion: bones widen and thicken
FSH Follicle Stimulating Hormone
Gland: APG
Target: Ovaries and testes
-Male development of sperm, female development of follicles in ovary
-HYPOsecretion: reduced estrogen, stunted sexual and sperm development
-HYPERsecretion: follicles that develop increase (result in cysts)
LH Luteinizing Hormone
Gland: APG
Target: Ovaries and testes
-Male production of testosterone, female ovulation and production of estrogen
-HYPOsecretion: underdeveloped sex organs
-HYPERsecretion: early development
MSH Melanocyte Stimulating Hormone
Gland: APG
Target: Most body cells
Function: Pigment production
PRL Prolactin
Gland: APG
Target: Mammary gland
-Milk production
-HYPOsecretion: reduced milk production
-HYPERsecretion: excessive milk production
O Oxytocin
Gland: PPG
Target: Mammary gland and uterus
-Milk release, cramps, and labour
-HYPOsecretion: delayed labour, limited amounts of milk
-HYPERsecretion: early labour, milk spurts out easily (overproduction)
ADH Antidiuretic Hormone
Gland: PPG
Target: Kidney
-Stops water loss, reabsorbs water into blood
-HYPOsecretion: large amounts of urine (urine diluted/light in color), causes thirst and dehydration
-HYPERsecretion: small amounts of urine (urine concentrated/dark in color), causes bloating and swelling
Pineal Gland Hormones
Melatonin
Anterior Pituitary Gland Hormones
hG Human Growth Hormone
FSH Follicle Stimulating Hormone
TSH Thyroid Stimulating Hormone
LH Luteinizing Hormone
ACTH Adrenocorticotropic Hormone
PRL Prolactin
MSH Melanocyte Stimulating Hormone
Posterior Pituitary Gland Hormones
O Oxytocin
ADH Antidiuretic Hormone
Hypothalamus Hormones
GnRH Gonadotropic releasing hormone
Hypothalamus gland
-produces releasing hormones that control hormones from APG
-produces ADH and oxytocin in the PPG
Pituitary gland
-controlled by hypothalamus
-at base of brain, size of a pea
-two lobes: anterior and posterior
Anterior lobe (front)
-produces and secretes hormones
-regulated by hypothalamus by releasing hormones
Posterior lobe (back)
-stores and secretes hormones produced by hypothalamus
-secretion stimulated by nerves
Positive feedback loop
-enhances hormone to be synthesized until desire effect is achieved (ex: furnace in home turning off after reaching perf. temp)
Negative feedback loop
-switches off hormone synthesis to maintain homeostasis (ex: furnace still heating after reaching perf. temp)
Hormones
-chemical messengers produced by endo. system glands
-secreted into bloodstream
-travel via circulatory system to target cells
-not all affect all cells
-levels always changing
Target cells
what a hormone has an effect on
Endocrine system
-helps control body responses
-glands are scattered throughout the body (connected by bloodstream)
-glands release hormones
Thyroid gland
-base of neck
-produces thyroxin and calcitonin
Thyroxin
Gland: Thyroid
Target: most body cells
-increases rate of metabolism
-HYPOsecretion: low metabolic rate, weight gain, cold/slow pulse
(cretinism (kids): stunted growth, mental delay + myxdema (adults): weight gain, hair loss, dry skin)
-HYPERsecretion: high metabolic rate, increased heart rate, weight loss, hot
Calcitonin
Gland: Thyroid
Target: bones
-moves calcium into bones from blood
-lowers calcium level in blood
-HYPOsecretion: excess calcium in blood; less in bones, weaker bone structure
-HYPERsecretion: low blood calcium
Negative feedback loop (thyroxine)
-levels too high = hypothalamus stops sending TRH to APG (stops stimulation of thyroid gland and the production of thyroxine)
-levels too low = hypothalamus sends more TRH to APG (produces more TSH > stimulates thyroid gland > produces more thyroxine)
Parathyroid gland
-4 at surface of thyroid
-releases PTH
PTH Parathyroid Hormone
Gland: PT
Target: blood and bones
-moves calcium from bones into blood
-raises calcium level in blood
-HYPOsecretion: low calcium levels (stunt growth, cramps)
-HYPERsecretion: high calcium levels in blood/urine
Pancreas
-secretes 2 hormones (insulin and glucagon)
-remember PIG acronym
Glycogen
-storage of excess sugar
-in liver and muscles
Glucagon
Target: liver
-hormone released by pancreas
-raises blood glucose levels by converting glycogen to glucose
-HYPOsecretion: hypoglycemia (low blood sugar)
-HYPERsecretion: hyperglycemia (high blood sugar)
Insulin
Target: body cells & liver
-lowers blood glucose levels
-causes liver and muscles to convert glucose to glycogen
-causes body cells to absorb more sugar for metabolism
-HYPOsecretion: diabetes mellitus (sugar) or hyperglycemia
-HYPERsecretion: hypoglycemia
Adrenal glands
-on top of kidneys
-two parts: cortex and medulla
Medulla
Target: body cells
Gland: adrenal (middle)
-produces 2 hormones (epinephrine/norepinephrine)
-increases heart rate, relaxes bronchi, dilates pupils and blood vessels, converts glycogen to glucose, increases cell metabolism
-HYPOsecretion: inability to deal with stress well
-HYPERsecretion: nervousness, high blood pressure, sweating, fast pulse
Cortex
Gland: adrenal (outer)
-produces 3 hormones (cortisol, aldosterone, sex)
-released when ACTH stimulates this
Cortisol
Target: body cells
Gland: adrenal
-released during times of prolonged stress
-increases amount of amino acids in blood to convert into glucose, fats broken down to fatty acids (energy)
-HYPOsecretion: difficulty dealing with stress
-HYPERsecretion: illness as result of suppressed immune system
Epinephrine and Norepinephrine
-adrenaline and noradrenaline
-controlled by hypothalamus and sympathetic nervous system
-prepares body to meet some emergency
Aldosterone
-trigger is low blood volume/pressure (kidneys send message via chemicals to AC > releases aldo > kidneys reabsorb Na+ > water is reabsorbed > blood vol/pressure goes up)
-increases sodium retention and water reabsorption by kidneys to maintain body fluid levels
-HYPOsecretion: decrease in blood pressure
-HYPERsecretion: increase in blood pressure
Androgen
Target: body cells
Gland: adrenal
-development of male secondary sex characteristics
-HYPOsecretion: no big change in males, decreased sex drive in females
-HYPERsecretion: masculinization of females (beards/lower voices)
GnRH Gonadotropic releasing hormone
Target: pituitary gland
Gland: hypothalamus
-causes release of FSH and LH from anterior pituitary starting at puberty
-HYPOsecretion: insufficient production of FSH and LH, late onset of puberty
-HYPERsecretion: overproduction of FSH and LH, early onset of puberty
Testes
Target: body cells
Gland: Gonads
-interstitial cells produce testosteroe
-onset of sperm production and enlargement of penis, testes, and prostate
-HYPOsecretion: shrinkage of testis and growth of breasts
-HYPERsecretion: aggression
Ovaries
-produce 2 hormones (estrogen and progesterone)
Estrogen
Target: uterine lining and body cells
Gland: gonads (ovaries)
-buildup of uterine lining (period in women), develops/maintains secondary sex characteristics
-HYPOsecretion: underdevelopment of endometrium (uterus lining: lighter period flow)
-HYPERsecretion: overdevelopment of endometrium (heavier period flow)
Progesterone
Target: uterine lining
Gland: gonads (ovaries)
-promotes growth of uterine lining for implantation, slows uterine contractions (tightening/relaxing)
-HYPOsecretion: underdevelopment of endometrium and uterine contractions
-HYPERsecretion: overdevelopment of endometrium and the slowing of uterine contractions