Cervico-Vaginal smears cells

Mature superficial

Polygonal + pink cytoplasm + dark pyknotic nuclei

Mature superficial

Abundant during proliferating phase

Mature superficial

True acidophilia / Pseudoacidophilia

Intermediate

Medium polyhedral/elongated cells + basic cytoplasm + vacuoles

Intermediate

Abundant during secretory phase (14-28 days; progesterone)

Navicular

Boat-shaped + curl edges

Navicular

Estrogen-progesterone effect

Navicular

Latter half of menstrual, pregnancy, and menopause

Pregnancy

Translucent basophilic cytoplasm at the center due to glycogen

Pregnancy

Double walled with deep blue stain at cytoplasm periphery

Parabasal

Thick/round to oval + smaller than intermediate cells

Parabasal

Smaller Strongly basophilic cytoplasm

Parabasal

Larger vesicular cytoplasm than intermediate cells

Parabasal

2 weeks of age to puberty, after childbirth, abortions, and menopausal

Basal

Small, round, slightly oval with large nuclei (half of cell volume)

Basal

Strongly basophilic cytoplasm

Basal

Before puberty and after menopause

Endometrial

Cylindrical + like parabasal cells

Endometrial

Less basophilic cytoplasm

Endometrial

1-4 days after menstruation

Endocervical Grandular

Fully vacuolated + pale blue/gray cytoplasm

Endocervical Grandular

Honeycomb/ large group appearance

Endocervical Grandular

Found in pap smear and may be a sign of cancer

Doderlein bacilli

Most common normal vagina flora

Doderlein bacilli

Numerous in: last trimester of pregnancy, infection, estrogen deficiency, DM

Doderlein bacilli

Decreased leads to increased of lepthothrix spp. (Trichomonas vaginalis)

Ferning phenomenon

Dried cervical mucus

Ferning phenomenon

Persistent estrogen effect

Ferning phenomenon

Early pregnancy diagnosis