Toxicity and Poisoning

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4 Terms

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•Hepatotoxicity

•Damage to liver cells can impair medication metabolism and cause accumulation in the body or alter LFT's

•Draw LFT's on patients starting a hepatotoxic drug.

•Monitor for abdominal pain, jaundice, dark urine, and fatigue.

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Nephrotoxicity

•Typically due to antimicrobials and NSAIDs

•Impaired kidney function leads to decreased excretion and accumulation

•Watch out for urine output changes, increased BUN and Creatinine

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poisoning

•When an overdose of a drug damages multiple systems

•Can be fatal

•Treatment varies based on drug

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