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Flashcards based on lecture notes covering evolutionary theories, natural selection, and adaptation.
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What type of process did Darwin propose for evolution?
A variational process of evolution proposed by Darwin.
What is the term for the tree of life diagram showing the descent of species?
Phylogeny
What kind of evolutionary process did Lamarck propose?
Transformational process
What was Lamarck's ladder-evolution hypothesis?
That species transform into more complex forms over time, with simpler forms continually reappearing.
What did Charles Lyell reveal that impacted Darwin's understanding of evolution?
Discovering that the Earth is millions of years old
What is homology?
Similarity in structure due to inheritance from a common ancestor.
What is natural selection?
A mechanism for gradual evolution of differences; population matches the aspect of the environment from which competition arises
What is adaptation?
The process by which a population optimally matches the aspect of the environment from which competition arises.
What part of the Evolutionary Tree represents common ancestors?
Interior nodes
When examining an evolutionary tree, what should you focus on?
Focus on the ordering of the branching events and ignoring the timing.
What is a monophyletic group (clade)?
A group of organisms that share a common ancestor and all of its descendants.
What is a paraphyletic group?
A group of organisms that share a common ancestor but do not include all of its descendants.
What is a polyphyletic group?
A taxonomic group of organisms that share similar traits but do not share a common ancestor
What is species relatedness?
How closely two or more species are connected through their evolutionary history
What is an unrooted phylogeny?
A diagram that shows the evolutionary relationships between organisms without indicating a common ancestor or the direction of evolution
What is a rooted phylogeny?
A phylogenetic tree that has a single branch representing a common ancestor of all the species in the tree
What is a polytomy?
A node in a phylogenetic tree where more than two lineages branch off from a single ancestral lineage
What are sister taxa?
Two organisms that branch off the same node.
What is Synapomorphy?
Shared derived character
What is Homoplasy?
The character evolves independently on two branches
What is Symplesiomorphy?
The character was present in the common ancestor but got lost along some branches
What is an outgroup?
A species (or group of species) that is related to the clade of interest but which branched off earlier in evolutionary history.
What does parsimony suggest about evolution?
The most parsimonious tree has the lowest number of evolutionary changes.
According to the Parsimony Method, what should you do when data is unattainable?
When data is unattainable go simple
When building phylogenies what can characters be?
Character states can be nucleotides along a DNA sequence
What is bootstrapping?
Random sampling method to find the best tree
What is phylogeny/ cladogram?
A graph that shows how well sequence data fits
What is a phenotype?
The observable characteristics of an organism.
In artificial selection, who or what is the selective agent?
The selective agent is the human breeder.
What are the components of natural selection?
Individual members of a population differ from one another, and some of these differences are transmitted from parent to offspring; Individuals with certain traits are more successful than others at surviving and reproducing in their environment (higher fitness)
What is breeders equation?
R = S x h2
What is adaptation?
A population response to a change in the environment.
What is acclimation?
An individual response to a change in the environment.
What is coevolution?
The process in which evolutionary changes to traits in species 1 drive changes in species 2, feeding back into one.
What is sexual selection?
A form of natural selection which acts on heritable variation in traits that directly influence reproduction, mating, and fertilization.
What is good genes hypothesis?
Extravagant traits signal male genetic quality; Choosing physically attractive males will lead to more attractive sons and more grandchildren
What is exaptation?
An adaptation that later is selected for a different function.
What is sexual conflict?
Selection in which mates are gained in one sex at some cost to the other.
How can you affect phenotypic variation?
Chromosomal recombination is possible; the production of gametes (by meiosis
What does Quantitative Trait Locus (QTL) analysis do?
Links two types of information, phenotypic data (trait measurements) and genotypic data (molecular makers)
What are H-W principle allele frequencies?
P = Frequency of allele b; 1= 1-p = Frequency of allele W; BB= p2; BW= 2pq; WW= q2
How does drift affect allele frequencies?
Causes genetic variation to decrease within populations, Some alleles are fixed, some are lost, heterozygosity decreases; causes populations to diverge by chance; increases genetic variation between generations
What effect do mutations have on fitness?
The fitness effects of mutations can be studied in a controlled lab; mutations affect fitness by altering protein function; mutations can range from positive-neutral-deleterious-lethal
What is Linkage Disequilibrium?
2 alleles occur together on the same chromosome more often than can be random chance
How is Linkage Disequilibrium determined?
Frequency of AB) x (frequency of ab) - (frequency of Ab) x (frequency of aB)
What are the two population speciations?
Dispersal and vicariance
What is Dobzhansky- Muller genetic incompatibility?
Negative epistasis between alleles; Essential mechanism that makes reproductive isolation and speciation irreversible
What two forces together predict adaptive radiation?
Ecological opportunity and sexual selection
What type of mutations does The Ka/Ks (dN/dS) test of selection look for?
Nonsynonymous mutations that are deleterious will be eliminated by purifying selection
What are primiate characteristics?
Dextrous hands, large brains, range of motion, color vision, etc
What are Hominins?
Members of the human side of the phylogenetic split from the chimpanzees
What two important processes were key to human expansion?
Natural selection and adaptation
Where did the EPAS1 gene in Tibetans come from?
It was acquired by interbreeding prior to the divergence
Why do genetic diseases persist?
Genetic Drift can drive deleterious mutations to fixation; Deleterious Alleles may persist in mutation-selection balance; Deleterious alleles may persist due to heterozygote advantage
What is linkage disequilibrium equation?
(F of AB) x (F of ab) - (F of Ab) x (F of aB)
Why is the global challenge of HIV to the human species so important?
Causes a dramatic decline in population health
What must a HIV variant do the be successful?
Replicate faster, be better at escaping the host immune defense, be able to infect more host cells
What is a prime mover of evolution?
Cooperation often acts as the driving force in evolution
What does Haplodiploidy entail?
The males of the species are clones and get either 1 of the 2 alleles from the mom; The females of the species also get either 1 of the 2 alleles from mom But also get the 1 allele from dad (dad only has 1 allele to give!!)
What is a Ribozyme?
RNA with catalytic enzyme properties
What can hypercycle mutations cause?
Altruistic Mutation; Defection Mutation
According to The tree of Life, what three domains emerged?
Individually diverged bacteria, archaea, and then eukaryotes
What are the two methods to multicellularity?
Aggregation: Coming together; Foregoing cell division: Staying together
What ate Hanschen individuality criteria?
Genetic Uniqueness, Genetic homogeneity, Division of labor, Indivisibility, Physiological unity and integration, spatial/temporal boundaries, group-level adaptions
What is pleiotropy?
One gene has several functions
What is Epistasis:
The phenotype for a certain gene depends on the presence of another gene
What is Antagonistic pleiotropy?
Trade offs
What are Paralogs?
A gene that is the same via duplication
What is the difference between orthologous and paralogs?
Orthologous- relation by speciation events; Paralogs- relation by duplication events
What does the Evolution of Complexity entail?
Evolution of new kinds of individuals; Hierarchical organization of life (Nestedness); Increased body cell; Division of labor; Increase in cell types; Spatial Patterns; New Genes
What is the paradox of sex?
Sex is costly; Sex is common
How can Sex induce variation?
Mixes, creates new combinations, reduces LD
What are the haploid disequilibrium outcomes?
Coupling Disequilibrium- AB and ab: extremely fit and extremely unfit individuals, slows evolution; Repulsion Disequilibrium- Ab and aB: both groups are equally and positively fit, accelerates evolution
According to Muller's Ratchet, how does sex help populations?
Sex helps populations deal with deleterious mutations
In The Red Queen Parasite Model, what disadvantage does the asexual clone encounter?
These parasites increase in frequency, resulting in a selective disadvantage to the asexual clone, which now decreases in frequency and often is lost in the population
What is Peto's Pardox?
The average number of mutations that occur during cellular division increases linearly with the size of the organism
What is the Meiossis timeline?
Present in LECA; evolved duplicated gene in prokaryotes
Is life immortal
Healthy genes; adaptation
What is Darwinian vs modern definition of evolutions?
Darwinian def. Evolution is descent with modification; Modern def. Evolution is the change in allele frequencies over time
What is adaptation in terms of generations?
A group level response over time
What is the Naturalistic Fallacy?
It is a fallacy to think that just because something is natural it is good or right; Evolution is not a moral system
What are limits of natural selection?
There are sexual conflicts or some individuals cannot express the best factors of ALL their traits/We have limited resources
What graphs show when and how long to adapt to pressures?
Trees; homoplasy and heritability also natural selection