MSK drugs

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Last updated 6:25 PM on 8/26/26
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8 Terms

1
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Cyclobenzaprine

Used for Muscle Spasm
MOA: CNS depression and sedation, centrally acting

2
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methocarbamol

Used for Muscle spasm
MOA: CNS depression and sedation, centrally acting

3
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Baclofen (Lioresal)

Used for Spasticity
MOA: GABA-B agonist in spinal cord, suppresses reflexes. Reduces muscle tone

4
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Diazepam (Valium)

Used for Spasticity
MOA: Benzodiazepine-Enhances GABA

5
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Glucocorticoids

Used for Rheumatoid Arthritis

6
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Methotrexate

Used for RA
MOA: Inhibits folate metabolism, which suppresses immune cell proliferation
(give with FOLIC ACID to reduce GI and Hepatic toxicity)

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Sulfasalazine

Anti-inflammatory and immunomodulatory effects, not active until its broken down by colonic bacteria

8
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Etanercept (Enbrel-Biologic)

used for RA
Suppresses inflammation by neutralizing TNF, preventing inflammatory signlaing